4YNK
 
 | | Crystal structure of vitamin D receptor ligand binding domain complexed with a 19-norvitamin D compound | | Descriptor: | (1R,3R,7E,17beta)-17-{(5S)-5-hydroxy-5-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-1-yl]penta-1,3-diyn-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, Coactivator peptide drip from cDNA FLJ50196, highly similar to Peroxisome proliferator-activated receptor-binding protein, ... | | Authors: | Watarai, Y, Ikura, T, Ito, N. | | Deposit date: | 2015-03-10 | | Release date: | 2016-01-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds
J.Med.Chem., 58, 2015
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4N0H
 | | Crystal structure of S. cerevisiae mitochondrial GatFAB | | Descriptor: | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glutamyl-tRNA(Gln) amidotransferase subunit B, ... | | Authors: | Araiso, Y, Ishitani, R, Nureki, O. | | Deposit date: | 2013-10-02 | | Release date: | 2014-04-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.952 Å) | | Cite: | Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases
Nucleic Acids Res., 42, 2014
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4N0I
 | | Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine | | Descriptor: | GLUTAMINE, Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, ... | | Authors: | Araiso, Y, Ishitani, R, Nureki, O. | | Deposit date: | 2013-10-02 | | Release date: | 2014-04-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases
Nucleic Acids Res., 42, 2014
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6JNF
 | | Cryo-EM structure of the translocator of the outer mitochondrial membrane | | Descriptor: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ... | | Authors: | Araiso, Y, Tsutsumi, A, Suzuki, J, Yunoki, K, Kawano, S, Kikkawa, M, Endo, T. | | Deposit date: | 2019-03-14 | | Release date: | 2019-10-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.81 Å) | | Cite: | Structure of the mitochondrial import gate reveals distinct preprotein paths.
Nature, 575, 2019
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2Z67
 | | Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) selenium transferase (SepSecS) | | Descriptor: | O-phosphoseryl-tRNA(Sec) selenium transferase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | Authors: | Araiso, Y, Ishitani, R, Pailouer, S, Oshikane, H, Domae, N, Soll, D, Nureki, O. | | Deposit date: | 2007-07-23 | | Release date: | 2008-04-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation.
Nucleic Acids Res., 36, 2008
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3A4M
 | | Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | | Authors: | Araiso, Y, Ishitani, R, Soll, D, Nureki, O. | | Deposit date: | 2009-07-10 | | Release date: | 2009-10-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.792 Å) | | Cite: | Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
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3AM1
 | | Crystal structure of O-Phosphoseryl-tRNA kinase complexed with anticodon-stem/loop truncated tRNA(Sec) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ASL-truncated tRNA, L-seryl-tRNA(Sec) kinase, ... | | Authors: | Araiso, Y, Ishitani, R, Nureki, O. | | Deposit date: | 2010-08-11 | | Release date: | 2010-12-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec)
Nucleic Acids Res., 39, 2011
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3A4N
 | | Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase | | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, L-seryl-tRNA(Sec) kinase, ... | | Authors: | Araiso, Y, Ishitani, R, Soll, D, Nureki, O. | | Deposit date: | 2009-07-10 | | Release date: | 2009-10-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
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3A4L
 | | Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase | | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, L-seryl-tRNA(Sec) kinase, ... | | Authors: | Araiso, Y, Ishitani, R, Soll, D, Nureki, O. | | Deposit date: | 2009-07-10 | | Release date: | 2009-10-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
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1VD4
 | | Solution structure of the zinc finger domain of TFIIE alpha | | Descriptor: | Transcription initiation factor IIE, alpha subunit, ZINC ION | | Authors: | Okuda, M, Tanaka, A, Arai, Y, Satoh, M, Okamura, H, Nagadoi, A, Hanaoka, F, Ohkuma, Y, Nishimura, Y. | | Deposit date: | 2004-03-18 | | Release date: | 2004-10-05 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.
J.Biol.Chem., 279, 2004
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8YVP
 | | canine immunoproteasome 20S subunit in complex with compound 1 | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Kashima, A, Arai, Y. | | Deposit date: | 2024-03-29 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
Bioorg.Med.Chem., 109, 2024
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8YPK
 | | mouse proteasome 20S subunit in complex with compound 1 | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Kashima, A, Arai, Y. | | Deposit date: | 2024-03-17 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
Bioorg.Med.Chem., 109, 2024
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8YVG
 | | canine immunoproteasome 20S subunit in complex with compound 1 | | Descriptor: | Proteasome subunit alpha type, Proteasome subunit beta, Proteasome subunit beta type-8, ... | | Authors: | Kashima, A, Arai, Y. | | Deposit date: | 2024-03-28 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
Bioorg.Med.Chem., 109, 2024
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8YSX
 | | canine immunoproteasome 20S subunit in complex with compound 2 | | Descriptor: | Proteasome subunit alpha type, Proteasome subunit beta, Proteasome subunit beta type-8, ... | | Authors: | Kashima, A, Arai, Y. | | Deposit date: | 2024-03-24 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
Bioorg.Med.Chem., 109, 2024
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3UG0
 | | Crystal structure of a Trp-less green fluorescent protein translated by the simplified genetic code | | Descriptor: | Green fluorescent protein | | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | | Deposit date: | 2011-11-02 | | Release date: | 2012-10-17 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.093 Å) | | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids.
Nucleic Acids Res., 40, 2012
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3UFZ
 | | Crystal structure of a Trp-less green fluorescent protein translated by the universal genetic code | | Descriptor: | Green fluorescent protein | | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | | Deposit date: | 2011-11-02 | | Release date: | 2012-10-17 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids.
Nucleic Acids Res., 40, 2012
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2ZNI
 | | Crystal structure of Pyrrolysyl-tRNA synthetase-tRNA(Pyl) complex from Desulfitobacterium hafniense | | Descriptor: | CALCIUM ION, Pyrrolysyl-tRNA synthetase, bacterial tRNA | | Authors: | Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O. | | Deposit date: | 2008-04-25 | | Release date: | 2008-12-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature, 457, 2009
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3AL5
 | | Crystal structure of Human TYW5 | | Descriptor: | JmjC domain-containing protein C2orf60, MAGNESIUM ION | | Authors: | Kato, M, Araiso, Y, Ishitani, R, Nureki, O. | | Deposit date: | 2010-07-26 | | Release date: | 2010-11-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Nucleic Acids Res., 39, 2011
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2ZNJ
 | | Crystal structure of Pyrrolysyl-tRNA synthetase from Desulfitobacterium hafniense | | Descriptor: | Putative uncharacterized protein | | Authors: | Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O. | | Deposit date: | 2008-04-25 | | Release date: | 2008-12-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature, 457, 2009
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3AL6
 | | Crystal structure of Human TYW5 | | Descriptor: | 2-OXOGLUTARIC ACID, JmjC domain-containing protein C2orf60, NICKEL (II) ION | | Authors: | Kato, M, Araiso, Y, Ishitani, R, Nureki, O. | | Deposit date: | 2010-07-26 | | Release date: | 2010-12-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Nucleic Acids Res., 39, 2011
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