5D1Y
 
 | | Low resolution crystal structure of human ribonucleotide reductase alpha6 hexamer in complex with dATP | | 分子名称: | Ribonucleoside-diphosphate reductase large subunit | | 著者 | Ando, N, Li, H, Brignole, E.J, Thompson, S, McLaughlin, M.I, Page, J, Asturias, F, Stubbe, J, Drennan, C.L. | | 登録日 | 2015-08-04 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (9.005 Å) | | 主引用文献 | Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.
Biochemistry, 55, 2016
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8DYZ
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8DZ7
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6M8F
 | | Engineered sperm whale myoglobin-based carbene transferase | | 分子名称: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | | 著者 | Bacik, J.P, Ando, N, Fasan, R. | | 登録日 | 2018-08-21 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Origin of high stereocontrol in olefin cyclopropanation catalyzed by an engineered carbene transferase.
Acs Catalysis, 9, 2019
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8ESU
 | | Myoglobin variant Mb-imi complex | | 分子名称: | IMIDAZOLE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Bacik, J.P, Fasan, R, Ando, N. | | 登録日 | 2022-10-14 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone.
Nat Commun, 14, 2023
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7SPG
 | | Crystal structure of sperm whale myoglobin variant sMb13(pCaaF) in space group P212121 | | 分子名称: | CHLORIDE ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Bacik, J.P, Fasan, R, Ando, N. | | 登録日 | 2021-11-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization.
Biochemistry, 61, 2022
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7SPH
 | | Crystal structure of sperm whale myoglobin variant sMb13(pCaaF) in space group P21 | | 分子名称: | Myoglobin, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Bacik, J.P, Fasan, R, Ando, N. | | 登録日 | 2021-11-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization.
Biochemistry, 61, 2022
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7SPE
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7SPF
 | | Crystal structure of sperm whale myoglobin variant sMb5(pCaaF) | | 分子名称: | Myoglobin, NITRATE ION, OXYGEN MOLECULE, ... | | 著者 | Bacik, J.P, Fasan, R, Ando, N. | | 登録日 | 2021-11-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization.
Biochemistry, 61, 2022
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8G3H
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6UYK
 | | Dark-operative protochlorophyllide oxidoreductase in the nucleotide-free form. | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | | 著者 | Bacik, J.P, Imran, S.M.S, Watkins, M.B, Corless, E, Antony, E, Ando, N. | | 登録日 | 2019-11-13 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The flexible N-terminus of BchL autoinhibits activity through interaction with its [4Fe-4S] cluster and released upon ATP binding.
J.Biol.Chem., 296, 2020
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8ESS
 | | Myoglobin variant Mb-cIII complex | | 分子名称: | Myoglobin, SULFATE ION, [2,18-bis(2-carboxyethyl)-7,12-diethenyl-3,8,13,17-tetramethyl-21-(2-oxo-3-phenylpropyl)porphyrin-21-iumato(2-)-kappa~3~N~22~,N~23~,N~24~]iron(2+) | | 著者 | Bacik, J.P, Fasan, R, Ando, N. | | 登録日 | 2022-10-14 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone.
Nat Commun, 14, 2023
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7URG
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5V1Q
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5V1S
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5V1T
 | | Crystal structure of Streptococcus suis SuiB bound to precursor peptide SuiA | | 分子名称: | IRON/SULFUR CLUSTER, METHIONINE, Radical SAM, ... | | 著者 | Davis, K.M, Bacik, J.P, Ando, N. | | 登録日 | 2017-03-02 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6MV9
 | | X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase, ... | | 著者 | Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. | | 登録日 | 2018-10-24 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
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6MT9
 | | X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. | | 登録日 | 2018-10-19 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
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6MVE
 | | Reduced X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP, ATP, and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Thomas, W.C, Brooks, F.P, Bacik, J.P, Ando, N. | | 登録日 | 2018-10-25 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
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6MYX
 | | EM structure of Bacillus subtilis ribonucleotide reductase inhibited double-helical filament of NrdE alpha subunit with dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase | | 著者 | Thomas, W.C, Bacik, J.P, Chen, J.Z, Ando, N. | | 登録日 | 2018-11-02 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
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6MW3
 | | EM structure of Bacillus subtilis ribonucleotide reductase inhibited filament composed of NrdE alpha subunit and NrdF beta subunit with dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase, Ribonucleoside-diphosphate reductase NrdF beta subunit | | 著者 | Thomas, W.C, Bacik, J.P, Kaelber, J.T, Ando, N. | | 登録日 | 2018-10-29 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.65 Å) | | 主引用文献 | Convergent allostery in ribonucleotide reductase.
Nat Commun, 10, 2019
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6O2H
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1B2W
 | | COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | | 分子名称: | PROTEIN (ANTIBODY (HEAVY CHAIN)), PROTEIN (ANTIBODY (LIGHT CHAIN)) | | 著者 | Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasquez, M, Queen, C, Ramsland, P.A, Edmundson, A.B. | | 登録日 | 1998-12-01 | | 公開日 | 1999-05-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
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1B4J
 | | COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | | 分子名称: | ANTIBODY | | 著者 | Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasques, M, Queen, C, Ramsland, P.A, Edmundson, A.B. | | 登録日 | 1998-12-22 | | 公開日 | 1999-06-15 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
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2I7U
 | | Structural and Dynamical Analysis of a Four-Alpha-Helix Bundle with Designed Anesthetic Binding Pockets | | 分子名称: | Four-alpha-helix bundle | | 著者 | Ma, D, Brandon, N.R, Cui, T, Bondarenko, V, Canlas, C, Johansson, J.S, Tang, P, Xu, Y. | | 登録日 | 2006-08-31 | | 公開日 | 2007-09-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses.
Biophys.J., 94, 2008
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