9B8M
 
 | | Crystal structure of ornithine decarboxylase in complex with a novel inhibitor | | Descriptor: | O-{[(3R)-pyrrolidin-3-yl]methyl}hydroxylamine, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Schultz, C.R, Aleiwi, B, Zhou, X.E, Suino-Powell, K, Melcher, K, Brunzelle, J.S, Almeida, N.M.S, Wilson, A.K, Ellsworth, E, Bachmann, A.S. | | Deposit date: | 2024-03-31 | | Release date: | 2025-03-12 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors.
J.Med.Chem., 68, 2025
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9B8N
 | | Crystal structure of ornithine decarboxylase in complex with a novel inhibitor (10-S) | | Descriptor: | O-{[(3S)-pyrrolidin-3-yl]methyl}hydroxylamine, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Schultz, C.R, Aleiwi, B, Zhou, X.E, Suino-Powell, K, Melcher, K, Brunzelle, J.S, Almeida, N.M.S, Wilson, A.K, Ellsworth, E, Bachmann, A.S. | | Deposit date: | 2024-03-31 | | Release date: | 2025-03-12 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors.
J.Med.Chem., 68, 2025
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7S3G
 | | Structure of cofactor pyridoxal 5-phosphate bound human ornithine decarboxylase in complex with citrate at the catalytic center | | Descriptor: | CITRIC ACID, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Zhou, X.E, Suino-Powell, K, Schultz, C.R, Aleiwi, B, Brunzelle, J.S, Lamp, J, Vega, I.E, Ellsworth, E, Bachmann, A.S, Melcher, K. | | Deposit date: | 2021-09-06 | | Release date: | 2021-12-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane.
Biochem.J., 478, 2021
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7S3F
 | | Structure of cofactor pyridoxal 5-phosphate bound human ornithine decarboxylase in complex with its inhibitor 1-amino-oxy-3-aminopropane | | Descriptor: | 3-AMINOOXY-1-AMINOPROPANE, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Zhou, X.E, Suino-Powell, K, Schultz, C.R, Aleiwi, B, Brunzelle, J.S, Lamp, J, Vega, I.E, Ellsworth, E, Bachmann, A.S, Melcher, K. | | Deposit date: | 2021-09-06 | | Release date: | 2021-12-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane.
Biochem.J., 478, 2021
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