Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 19 件
4WGK
DownloadVisualize
BU of 4wgk by Molmil
Crystal structure of human neutral ceramidase with Zn-bound phosphate
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Airola, M.V, Pulkoski-Gross, M.J, Obeid, L.M, Hannun, Y.A.
登録日2014-09-18
公開日2015-07-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
Structure, 23, 2015
5UVG
DownloadVisualize
BU of 5uvg by Molmil
Crystal structure of the human neutral sphingomyelinase 2 (nSMase2) catalytic domain with insertion deleted and calcium bound
分子名称: CALCIUM ION, Sphingomyelin phosphodiesterase 3,Sphingomyelin phosphodiesterase 3
著者Airola, M.V, Guja, K.E, Garcia-Diaz, M, Hannun, Y.A.
登録日2017-02-20
公開日2017-06-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3LNR
DownloadVisualize
BU of 3lnr by Molmil
Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION
著者Airola, M.V, Bilwes, A.M, Crane, B.R.
登録日2010-02-02
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of concatenated HAMP domains provides a mechanism for signal transduction.
Structure, 18, 2010
4HI4
DownloadVisualize
BU of 4hi4 by Molmil
Crystal structure of the 5-coordinate ferric heme-binding PAS domain of Aer2 from P. aeruginosa
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION, GLYCEROL, ...
著者Airola, M.V, Crane, B.R.
登録日2012-10-11
公開日2013-01-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling.
J.Mol.Biol., 425, 2013
4I44
DownloadVisualize
BU of 4i44 by Molmil
Aer2 poly-HAMP domains: V33G HAMP1 inverted signaling mutant
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION
著者Airola, M.V, Sukomon, N, Crane, B.R.
登録日2012-11-27
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors.
Plos Biol., 11, 2013
4I3M
DownloadVisualize
BU of 4i3m by Molmil
Aer2 poly-HAMP domains: L44H HAMP1 CW-lock mutant
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION, MAGNESIUM ION, ...
著者Airola, M.V, Sukomon, N, Crane, B.R.
登録日2012-11-26
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors.
Plos Biol., 11, 2013
7LHK
DownloadVisualize
BU of 7lhk by Molmil
High-Resolution Crystal Structure of a Lipin/Pah Phosphatidic Acid Phosphatase
分子名称: CACODYLATE ION, Nuclear elongation and deformation protein
著者Khayyo, V.I, Airola, M.V.
登録日2021-01-25
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献High-resolution structure of phosphatidic acid phosphohydrolase from Tetrahymena thermophila
To be published
8EXD
DownloadVisualize
BU of 8exd by Molmil
Crystal structure of Aspergillus fumigatus sterylglucosidase A
分子名称: Sterylglucosidase A (SglA)
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2022-10-25
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections.
Mbio, 14, 2023
8UJM
DownloadVisualize
BU of 8ujm by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex with magnesium
分子名称: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1, MAGNESIUM ION
著者Gao, S, Airola, M.V.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.161 Å)
主引用文献Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UJL
DownloadVisualize
BU of 8ujl by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex
分子名称: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1
著者Gao, S, Airola, M.V.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
6TZZ
DownloadVisualize
BU of 6tzz by Molmil
Crystal Structure of Tetrahymena Thermophila Lipin Phosphatidic Acid Phosphatase with Magnesium
分子名称: MAGNESIUM ION, Nuclear elongation and deformation protein
著者Khayyo, V.I, Airola, M.V.
登録日2019-08-13
公開日2020-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a lipin/Pah phosphatidic acid phosphatase
Nat Commun, 11, 2020
6TZY
DownloadVisualize
BU of 6tzy by Molmil
Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
分子名称: CALCIUM ION, Nuclear elongation and deformation protein
著者Khayyo, V.I, Airola, M.V.
登録日2019-08-13
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
Nat Commun, 11, 2020
6U8Z
DownloadVisualize
BU of 6u8z by Molmil
Crystal Structure of Catalytic Domain of Human Phospholipase D1
分子名称: PHOSPHITE ION, Phospholipase D1,Phospholipase D1
著者Bowling, F.Z, Airola, M.V.
登録日2019-09-06
公開日2020-03-18
最終更新日2020-04-01
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2and RhoA.
Nat.Chem.Biol., 16, 2020
7KIL
DownloadVisualize
BU of 7kil by Molmil
Crystal structure of the mouse lipin-1 M-Lip domain with zinc
分子名称: CHLORIDE ION, Isoform 2 of Phosphatidate phosphatase LPIN1, ZINC ION
著者Gu, W, Airola, M.V.
登録日2020-10-23
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献The middle lipin domain adopts a membrane-binding dimeric protein fold.
Nat Commun, 12, 2021
7KIQ
DownloadVisualize
BU of 7kiq by Molmil
Crystal structure of the mouse lipin-2 M-Lip domain
分子名称: CALCIUM ION, Phosphatidate phosphatase LPIN2
著者Yang, J.W, Gu, W, Airola, M.V.
登録日2020-10-24
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.523 Å)
主引用文献The middle lipin domain adopts a membrane-binding dimeric protein fold.
Nat Commun, 12, 2021
7KIH
DownloadVisualize
BU of 7kih by Molmil
Crystal structure of the mouse lipin-1 M-Lip domain
分子名称: Isoform 2 of Phosphatidate phosphatase LPIN1
著者Gu, W, Airola, M.V.
登録日2020-10-23
公開日2021-07-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.467 Å)
主引用文献The middle lipin domain adopts a membrane-binding dimeric protein fold.
Nat Commun, 12, 2021
7LPQ
DownloadVisualize
BU of 7lpq by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 9
分子名称: Cytoplasmic protein, GLYCEROL, MAGNESIUM ION, ...
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2021-02-12
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LPP
DownloadVisualize
BU of 7lpp by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 1
分子名称: 4-(hydroxymethyl)-1-[[2-(3-methoxyphenyl)-1,3-thiazol-5-yl]methyl]piperidin-4-ol, Cytoplasmic protein, GLYCEROL, ...
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2021-02-12
公開日2021-09-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LPO
DownloadVisualize
BU of 7lpo by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with tris
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytoplasmic protein, MAGNESIUM ION
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2021-02-12
公開日2021-09-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon