8VJY
 
 | |
8VJX
 | |
8VA0
 | | X-ray crystal structure of JGFN4 N76D complexed with fentanyl in dimer form | | 分子名称: | 1,2-ETHANEDIOL, JGFN4, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, ... | | 著者 | Shi, K, Moller, N, Aihara, H. | | 登録日 | 2023-12-10 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl.
J.Biol.Chem., 300, 2024
|
|
8V9X
 | | X-ray crystal structure of JGFN4 complex with fentanyl | | 分子名称: | 1,2-ETHANEDIOL, JGFN4, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide | | 著者 | Moller, N, Shi, K, Aihara, H. | | 登録日 | 2023-12-10 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl.
J.Biol.Chem., 300, 2024
|
|
8V9W
 | | X-ray crystal structure of JGFN4 complexed with fentanyl | | 分子名称: | 1,2-ETHANEDIOL, JGFN4, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide | | 著者 | Moller, N, Shi, K, Aihara, H. | | 登録日 | 2023-12-10 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl.
J.Biol.Chem., 300, 2024
|
|
6VOY
 | | Cryo-EM structure of HTLV-1 instasome | | 分子名称: | DNA (25-MER), DNA (5'-D(P*AP*CP*AP*CP*AP*CP*TP*TP*GP*AP*CP*TP*AP*GP*GP*GP*TP*G)-3'), DNA-binding protein 7d, ... | | 著者 | Bhatt, V, Shi, K, Sundborger, A, Aihara, H. | | 登録日 | 2020-02-01 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis of host protein hijacking in human T-cell leukemia virus integration.
Nat Commun, 11, 2020
|
|
6VK7
 | | Crystal Structure of reduced Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase | | 分子名称: | FE (III) ION, Methane monooxygenase, Methane monooxygenase component A alpha chain | | 著者 | Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D. | | 登録日 | 2020-01-18 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
|
|
6VK6
 | | Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ... | | 著者 | Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D. | | 登録日 | 2020-01-18 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
|
|
6U81
 | |
7S6S
 | | Complex structure of Methane monooxygenase hydroxylase and regulatory subunit DBL1 | | 分子名称: | 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... | | 著者 | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | | 登録日 | 2021-09-14 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics.
Biochemistry, 61, 2022
|
|
7S6T
 | | Complex structure of Methane monooxygenase hydroxylase and regulatory subunit H33A | | 分子名称: | 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... | | 著者 | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | | 登録日 | 2021-09-14 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics.
Biochemistry, 61, 2022
|
|
7SPP
 | |
7SPO
 | |
6VW1
 | | Structure of SARS-CoV-2 chimeric receptor-binding domain complexed with its receptor human ACE2 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Shang, J, Ye, G, Shi, K, Wan, Y.S, Aihara, H, Li, F. | | 登録日 | 2020-02-18 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural basis of receptor recognition by SARS-CoV-2.
Nature, 581, 2020
|
|
7KM6
 | | APOBEC3B antibody 5G7 Fv-clasp | | 分子名称: | 1,2-ETHANEDIOL, 5G7 human monoclonal FAB heavy chain, 5G7 human monoclonal FAB light chain, ... | | 著者 | Tang, H, Shi, K, Aihara, H. | | 登録日 | 2020-11-02 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural Characterization of a Minimal Antibody against Human APOBEC3B.
Viruses, 13, 2021
|
|
6DHJ
 | |
7TGR
 | | Structure of SARS-CoV-2 main protease in complex with GC376 | | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 1,2-ETHANEDIOL, ... | | 著者 | Esler, M.A, Shi, K, Aihara, H, Harris, R.S. | | 登録日 | 2022-01-09 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells.
Mbio, 13, 2022
|
|
6DT1
 | | Crystal structure of the ligase from bacteriophage T4 complexed with DNA intermediate | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | | 著者 | Shi, K, Aihara, H. | | 登録日 | 2018-06-14 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
Nucleic Acids Res., 46, 2018
|
|
7K30
 | | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with dU at the active site | | 分子名称: | 1,2-ETHANEDIOL, DNA (27-MER), Endonuclease Q, ... | | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | | 登録日 | 2020-09-10 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K31
 | | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with dI at the active site | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (27-MER), ... | | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | | 登録日 | 2020-09-10 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K32
 | | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with an abasic lesion at the active site | | 分子名称: | DNA (27-MER), Endonuclease Q, MAGNESIUM ION, ... | | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | | 登録日 | 2020-09-10 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K33
 | | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with an abasic lesion at the active site | | 分子名称: | DNA (27-MER), Endonuclease Q, MAGNESIUM ION, ... | | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | | 登録日 | 2020-09-10 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7JN3
 | | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048 | | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | | 登録日 | 2020-08-03 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Commun Biol, 4, 2021
|
|
7S7H
 | | Complex structure of Methane monooxygenase hydroxylase and regulatory subunit DBL2 | | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, Methane monooxygenase beta chain, ... | | 著者 | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | | 登録日 | 2021-09-16 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics.
Biochemistry, 61, 2022
|
|
7KUI
 | | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. CIC region of a cluster identified by 3-dimensional variability analysis in cryoSPARC. | | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | | 登録日 | 2020-11-25 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Commun Biol, 4, 2021
|
|
