2ZJR
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![BU of 2zjr by Molmil](/molmil-images/mine/2zjr) | Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans | Descriptor: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | Deposit date: | 2008-03-08 | Release date: | 2008-06-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol.Cell, 30, 2008
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4D5Y
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![BU of 4d5y by Molmil](/molmil-images/mine/4d5y) | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | Descriptor: | 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ... | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | Deposit date: | 2014-11-07 | Release date: | 2015-03-04 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State Mol.Cell, 57, 2015
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2IW3
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![BU of 2iw3 by Molmil](/molmil-images/mine/2iw3) | Elongation Factor 3 in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ELONGATION FACTOR 3A, SULFATE ION | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-06-26 | Release date: | 2006-08-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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2IX3
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![BU of 2ix3 by Molmil](/molmil-images/mine/2ix3) | Structure of yeast Elongation Factor 3 | Descriptor: | ELONGATION FACTOR 3, SULFATE ION | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-07-06 | Release date: | 2006-08-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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1FCW
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![BU of 1fcw by Molmil](/molmil-images/mine/1fcw) | TRNA POSITIONS DURING THE ELONGATION CYCLE | Descriptor: | TRNAPHE | Authors: | Agrawal, R.K, Spahn, C.M.T, Penczek, P, Grassucci, R.A, Nierhaus, K.H, Frank, J. | Deposit date: | 2000-07-19 | Release date: | 2000-08-11 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. J.Cell Biol., 150, 2000
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2IWH
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![BU of 2iwh by Molmil](/molmil-images/mine/2iwh) | Structure of yeast Elongation Factor 3 in complex with ADPNP | Descriptor: | ELONGATION FACTOR 3A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-06-30 | Release date: | 2006-08-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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8BEV
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![BU of 8bev by Molmil](/molmil-images/mine/8bev) | Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Lauer, S, Spahn, C.M.T, Schwefel, D. | Deposit date: | 2022-10-21 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (5.92 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD) To Be Published
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4D5N
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![BU of 4d5n by Molmil](/molmil-images/mine/4d5n) | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | Descriptor: | CRICKET PARALYSIS VIRUS IRES RNA, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | Deposit date: | 2014-11-06 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
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8BGG
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![BU of 8bgg by Molmil](/molmil-images/mine/8bgg) | Cryo-EM structure of SARS-CoV-2 spike (Omicron BA.1 variant) in complex with nanobody W25 (map 5, focus refinement on RBD, W25 and adjacent NTD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody W25, Spike glycoprotein, ... | Authors: | Modhiran, N, Lauer, S, Spahn, C.M.T, Watterson, D, Schwefel, D. | Deposit date: | 2022-10-27 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (6.04 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 spike (Omicron BA.1 variant) in complex with nanobody W25 (map 5, focus refinement on RBD, W25 and adjacent NTD) To Be Published
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2NOQ
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![BU of 2noq by Molmil](/molmil-images/mine/2noq) | Structure of ribosome-bound cricket paralysis virus IRES RNA | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ... | Authors: | Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T. | Deposit date: | 2006-10-26 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nat.Struct.Mol.Biol., 13, 2006
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3DEG
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![BU of 3deg by Molmil](/molmil-images/mine/3deg) | Complex of elongating Escherichia coli 70S ribosome and EF4(LepA)-GMPPNP | Descriptor: | 30S RNA helix 14, 30S RNA helix 8, 30S ribosomal protein S12, ... | Authors: | Connell, S.R, Topf, M, Qin, Y, Wilson, D.N, Mielke, T, Fucini, P, Nierhaus, K.H, Spahn, C.M.T. | Deposit date: | 2008-06-10 | Release date: | 2008-08-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (10.9 Å) | Cite: | A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation Nat.Struct.Mol.Biol., 15, 2008
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1P75
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![BU of 1p75 by Molmil](/molmil-images/mine/1p75) | Crystal structure of EHV4-TK complexed with TP5A | Descriptor: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, Thymidine kinase | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2003-04-30 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
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1YSH
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![BU of 1ysh by Molmil](/molmil-images/mine/1ysh) | Localization and dynamic behavior of ribosomal protein L30e | Descriptor: | 40S RIBOSOMAL PROTEIN S13, RNA (101-MER), RNA (28-MER), ... | Authors: | Halic, M, Becker, T, Frank, J, Spahn, C.M, Beckmann, R. | Deposit date: | 2005-02-08 | Release date: | 2005-07-05 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Localization and dynamic behavior of ribosomal protein L30e Nat.Struct.Mol.Biol., 12, 2005
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1EG0
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![BU of 1eg0 by Molmil](/molmil-images/mine/1eg0) | FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME | Descriptor: | FORMYL-METHIONYL-TRNA, FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, ... | Authors: | Gabashvili, I.S, Agrawal, R.K, Spahn, C.M.T, Grassucci, R.A, Svergun, D.I, Frank, J, Penczek, P. | Deposit date: | 2000-02-11 | Release date: | 2000-03-06 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (11.5 Å) | Cite: | Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell(Cambridge,Mass.), 100, 2000
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1P6X
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![BU of 1p6x by Molmil](/molmil-images/mine/1p6x) | Crystal structure of EHV4-TK complexed with Thy and SO4 | Descriptor: | SULFATE ION, THYMIDINE, Thymidine kinase | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2003-04-30 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
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1P7C
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![BU of 1p7c by Molmil](/molmil-images/mine/1p7c) | Crystal Structure of HSV1-TK complexed with TP5A | Descriptor: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, THYMIDINE, ... | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2003-05-01 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
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2IX8
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![BU of 2ix8 by Molmil](/molmil-images/mine/2ix8) | MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME | Descriptor: | ELONGATION FACTOR 3A | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-07-07 | Release date: | 2007-07-10 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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3RGW
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![BU of 3rgw by Molmil](/molmil-images/mine/3rgw) | Crystal structure at 1.5 A resolution of an H2-reduced, O2-tolerant hydrogenase from Ralstonia eutropha unmasks a novel iron-sulfur cluster | Descriptor: | FE3-S4 CLUSTER, FE4-S3 CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Scheerer, P, Fritsch, J, Frielingsdorf, S, Kroschinsky, S, Friedrich, B, Lenz, O, Spahn, C.M.T. | Deposit date: | 2011-04-10 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre. Nature, 479, 2011
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1P5Z
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![BU of 1p5z by Molmil](/molmil-images/mine/1p5z) | Structure of human dCK complexed with cytarabine and ADP-MG | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CYTARABINE, Deoxycytidine kinase, ... | Authors: | Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2003-04-28 | Release date: | 2003-07-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of human dCK suggests strategies to improve anticancer and antiviral therapy Nat.Struct.Biol., 10, 2003
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1TRJ
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![BU of 1trj by Molmil](/molmil-images/mine/1trj) | Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome | Descriptor: | Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA | Authors: | Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J. | Deposit date: | 2004-06-21 | Release date: | 2004-09-28 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM Nat.Struct.Mol.Biol., 11, 2004
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1RY1
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![BU of 1ry1 by Molmil](/molmil-images/mine/1ry1) | Structure of the signal recognition particle interacting with the elongation-arrested ribosome | Descriptor: | SRP Alu domain, SRP RNA, SRP S domain, ... | Authors: | Halic, M, Becker, T, Pool, M.R, Spahn, C.M, Grassucci, R.A, Frank, J, Beckmann, R. | Deposit date: | 2003-12-19 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structure of the signal recognition particle interacting with the elongation-arrested ribosome Nature, 427, 2004
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1T1M
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![BU of 1t1m by Molmil](/molmil-images/mine/1t1m) | Binding position of ribosome recycling factor (RRF) on the E. coli 70S ribosome | Descriptor: | 42-mer fragment of double helix from 16S rRNA, dodecamer fragment of double helix from 23S rRNA, ribosome recycling factor | Authors: | Agrawal, R.K, Sharma, M.R, Kiel, M.C, Hirokawa, G, Booth, T.M, Spahn, C.M, Grassucci, R.A, Kaji, A, Frank, J. | Deposit date: | 2004-04-16 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications Proc.Natl.Acad.Sci.USA, 101, 2004
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1T1O
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![BU of 1t1o by Molmil](/molmil-images/mine/1t1o) | Components of the control 70S ribosome to provide reference for the RRF binding site | Descriptor: | 19-mer fragment of the 23S rRNA, 42-mer fragment of double helix from 16S rRNA, dodecamer fragment of double helix from 23S rRNA | Authors: | Agrawal, R.K, Sharma, M.R, Kiel, M.C, Hirokawa, G, Booth, T.M, Spahn, C.M, Grassucci, R.A, Kaji, A, Frank, J. | Deposit date: | 2004-04-16 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications Proc.Natl.Acad.Sci.USA, 101, 2004
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1P73
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![BU of 1p73 by Molmil](/molmil-images/mine/1p73) | Crystal structure of EHV4-TK complexed with TP4A | Descriptor: | P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, SULFATE ION, Thymidine kinase | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2003-04-30 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
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2AXM
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![BU of 2axm by Molmil](/molmil-images/mine/2axm) | HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | Digabriele, A.D, Lax, I, Chen, D.I, Svahn, C.M, Jaye, M, Schlessinger, J, Hendrickson, W.A. | Deposit date: | 1997-10-20 | Release date: | 1998-04-22 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of a heparin-linked biologically active dimer of fibroblast growth factor. Nature, 393, 1998
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