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PDB: 318 件

6F0O
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Botulinum neurotoxin A3 Hc domain
分子名称: 1,2-ETHANEDIOL, Bontoxilysin A, PENTAETHYLENE GLYCOL, ...
著者Davies, J.R, Liu, S.M, Acharya, K.R.
登録日2017-11-20
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High resolution crystal structures of Clostridium botulinum neurotoxin A3 and A4 binding domains.
J. Struct. Biol., 202, 2018
6F9R
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Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with Sampatrilat-Asp.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R.
登録日2017-12-15
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity.
FEBS J., 285, 2018
6F9U
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Crystal structure of human testis Angiotensin-1 converting enzyme in complex with Sampatrilat-Asp.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Cozier, G.E, Acharya, K.R.
登録日2017-12-15
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity.
FEBS J., 285, 2018
6F9T
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Crystal structure of human testis Angiotensin-1 converting enzyme in complex with Sampatrilat.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R.
登録日2017-12-15
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity.
FEBS J., 285, 2018
6GID
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High resolution crystal structure of substrate-free human neprilysin
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Moss, S, Subramanian, V, Acharya, K.R.
登録日2018-05-10
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High resolution crystal structure of substrate-free human neprilysin.
J. Struct. Biol., 204, 2018
6H5X
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Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with Omapatrilat.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R.
登録日2018-07-25
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.
J. Med. Chem., 61, 2018
6H5W
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Crystal structure of human Angiotensin-1 converting enzyme C-domain in complex with Omapatrilat.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Cozier, G.E, Acharya, K.R.
登録日2018-07-25
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.
J. Med. Chem., 61, 2018
4S2R
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Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site
分子名称: Protein APP-1, ZINC ION
著者Iyer, S, La-Borde, P, Payne, K.A.P, Parsons, M.R, Turner, A.J, Isaac, R.E, Acharya, K.R.
登録日2015-01-22
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site.
FEBS Open Bio, 5, 2015
4S2T
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Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site
分子名称: Protein APP-1, SULFATE ION, ZINC ION, ...
著者Iyer, S, La-Borde, P, Payne, K.A.P, Parsons, M.R, Turner, A.J, Isaac, R.E, Acharya, K.R.
登録日2015-01-22
公開日2015-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site.
FEBS Open Bio, 5, 2015
1K58
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BU of 1k58 by Molmil
Crystal Structure of Human Angiogenin Variant D116H
分子名称: Angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K5B
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BU of 1k5b by Molmil
Crystal Structure of Human Angiogenin Variant des(121-123)
分子名称: Angiogenin, CITRIC ACID
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K59
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BU of 1k59 by Molmil
Crystal Structure of Human Angiogenin Variant Q117G
分子名称: CITRIC ACID, angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K5A
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BU of 1k5a by Molmil
Crystal structure of human angiogenin double variant I119A/F120A
分子名称: Angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1QHC
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BU of 1qhc by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-PHOSPHO-2'-DEOXYURIDINE-3'-PYROPHOSPHATE ADENOSINE-3'-PHOSPHATE
分子名称: ADENYLATE-3'-PHOSPHATE-[[2'-DEOXY-URIDINE-5'-PHOSPHATE]-3'-PHOSPHATE], PROTEIN (RIBONUCLEASE A)
著者Leonidas, D.D, Acharya, K.R.
登録日1999-05-12
公開日1999-08-31
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor.
Biochemistry, 38, 1999
1VZU
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BU of 1vzu by Molmil
Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K.
登録日2004-05-27
公開日2004-07-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
1VZX
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Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K.
登録日2004-05-28
公開日2004-07-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
4D5A
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BU of 4d5a by Molmil
Clostridial Cysteine protease Cwp84 C116A after propeptide cleavage
分子名称: CALCIUM ION, CELL SURFACE PROTEIN (PUTATIVE CELL SURFACE-ASSOCIATED CYSTEINE PROTEASE), GLYCEROL, ...
著者Bradshaw, W.J, Roberts, A.K, Shone, C.C, Acharya, K.R.
登録日2014-11-03
公開日2015-03-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cwp84, a Clostridium Difficile Cysteine Protease, Exhibits Conformational Flexibility in the Absence of its Propeptide
Acta Crystallogr.,Sect.F, 71, 2015
4D59
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Clostridial Cysteine protease Cwp84 C116A after propeptide cleavage
分子名称: CALCIUM ION, CELL SURFACE PROTEIN (PUTATIVE CELL SURFACE-ASSOCIATED CYSTEINE PROTEASE), O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
著者Bradshaw, W.J, Roberts, A.K, Shone, C.C, Acharya, K.R.
登録日2014-11-03
公開日2015-03-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Cwp84, a Clostridium Difficile Cysteine Protease, Exhibits Conformational Flexibility in the Absence of its Propeptide
Acta Crystallogr.,Sect.F, 71, 2015
2J0T
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BU of 2j0t by Molmil
Crystal Structure of the Catalytic Domain of MMP-1 in Complex with the Inhibitory Domain of TIMP-1
分子名称: CALCIUM ION, INTERSTITIAL COLLAGENASE, METALLOPROTEINASE INHIBITOR 1, ...
著者Iyer, S, Wei, S, Brew, K, Acharya, K.R.
登録日2006-08-04
公開日2006-10-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Crystal Structure of the Catalytic Domain of Matrix Metalloproteinase-1 in Complex with the Inhibitory Domain of Tissue Inhibitor of Metalloproteinase-1.
J.Biol.Chem., 282, 2007
2IVD
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BU of 2ivd by Molmil
Structure of protoporphyrinogen oxidase from Myxococcus xanthus with acifluorfen
分子名称: (3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Corradi, H.R, Corrigall, A.V, Boix, E, Mohan, C.G, Sturrock, E.D, Meissner, P.N, Acharya, K.R.
登録日2006-06-12
公開日2006-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus Xanthus and its Complex with the Inhibitor Acifluorfen.
J.Biol.Chem., 281, 2006
2JCO
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Crystal structure of wild type alpha-1,3 Galactosyltransferase in the absence of ligands
分子名称: GLYCEROL, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE
著者Jamaluddin, H, Tumbale, P, Withers, S.G, Acharya, K.R, Brew, K.
登録日2006-12-28
公開日2007-06-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis.
J.Mol.Biol., 369, 2007
2BZZ
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BU of 2bzz by Molmil
Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A
分子名称: ACETIC ACID, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, NONSECRETORY RIBONUCLEASE
著者Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R.
登録日2005-08-24
公開日2006-01-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
2J4T
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BU of 2j4t by Molmil
Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein
分子名称: ANGIOGENIN-4
著者Crabtree, B, Holloway, D.E, Baker, M.D, Acharya, K.R, Subramanian, V.
登録日2006-09-05
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein
Biochemistry, 46, 2007
2BWL
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Murine angiogenin, phosphate complex
分子名称: ANGIOGENIN, PHOSPHATE ION
著者Holloway, D.E, Chavali, G.B, Hares, M.C, Subramanian, V, Acharya, K.R.
登録日2005-07-15
公開日2005-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure of Murine Angiogenin: Features of the Substrate- and Cell-Binding Regions and Prospects for Inhibitor-Binding Studies.
Acta Crystallogr.,Sect.D, 61, 2005
2C6F
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Structure of human somatic angiontensin-I converting enzyme N domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Corradi, H.R, Schwager, S.L.U, Nichinda, A, Sturrock, E.D, Acharya, K.R.
登録日2005-11-09
公開日2006-11-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal Structure of the N Domain of Human Somatic Angiotensin I-Converting Enzyme Provides a Structural Basis for Domain-Specific Inhibitor Design.
J.Mol.Biol., 357, 2006

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