3WW6
 
 | | Crystal Structure of hen egg white lysozyme mutant N46D/D52S | | 分子名称: | CHLORIDE ION, Lysozyme C | | 著者 | Abe, Y, Kubota, M, Ito, Y, Imoto, T, Ueda, T. | | 登録日 | 2014-06-17 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme.
Protein Sci., 25, 2016
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3WW5
 | | Crystal Structure of hen egg white lysozyme mutant N46E/D52S | | 分子名称: | CHLORIDE ION, Lysozyme C | | 著者 | Abe, Y, Kubota, M, Ito, Y, Imoto, T, Ueda, T. | | 登録日 | 2014-06-17 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme.
Protein Sci., 25, 2016
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1OM2
 | | SOLUTION NMR STRUCTURE OF THE MITOCHONDRIAL PROTEIN IMPORT RECEPTOR TOM20 FROM RAT IN A COMPLEX WITH A PRESEQUENCE PEPTIDE DERIVED FROM RAT ALDEHYDE DEHYDROGENASE (ALDH) | | 分子名称: | PROTEIN (MITOCHONDRIAL ALDEHYDE DEHYDROGENASE), PROTEIN (MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20) | | 著者 | Abe, Y, Shodai, T, Muto, T, Mihara, K, Torii, H, Nishikawa, S, Endo, T, Kohda, D. | | 登録日 | 1999-04-23 | | 公開日 | 2000-02-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20.
Cell(Cambridge,Mass.), 100, 2000
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2RU8
 | | DnaT C-terminal domain | | 分子名称: | Primosomal protein 1 | | 著者 | Abe, Y, Tani, J, Fujiyama, S, Urabe, M, Sato, K, Aramaki, T, Katayama, T, Ueda, T. | | 登録日 | 2014-01-29 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and mechanism of the primosome protein DnaT-functional structures for homotrimerization, dissociation of ssDNA from the PriB·ssDNA complex, and formation of the DnaT·ssDNA complex.
Febs J., 281, 2014
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5YCQ
 | | Unique Specificity-Enhancing Factor for the AAA+ Lon Protease | | 分子名称: | Heat shock protein HspQ | | 著者 | Abe, Y, Shioi, S, Kita, S, Nakata, H, Maenaka, K, Kohda, D, Katayama, T, Ueda, T. | | 登録日 | 2017-09-08 | | 公開日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation
FEBS Lett., 591, 2017
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2RUP
 | | Solution structure of rat P2X4 receptor head domain | | 分子名称: | P2X purinoceptor 4 | | 著者 | Abe, Y, Igawa, T, Tsuda, M, Inoue, K, Ueda, T. | | 登録日 | 2014-11-12 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding
FEBS Lett., 589, 2015
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2D35
 | | Solution structure of Cell Division Reactivation Factor, CedA | | 分子名称: | Cell division activator cedA | | 著者 | Abe, Y, Watanabe, N, Matsuda, Y, Yoshida, Y, Katayama, T, Ueda, T. | | 登録日 | 2005-09-26 | | 公開日 | 2006-12-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Analysis and Molecular Interaction of Cell Division Reactivation Factor, CedA from Escherichia coli
To be Published
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6J7C
 | | Crystal structure of proline racemase-like protein from Thermococcus litoralis in complex with proline | | 分子名称: | PROLINE, Proline racemase | | 著者 | Watanabe, Y, Watanabe, S, Itoh, Y, Watanabe, Y. | | 登録日 | 2019-01-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of substrate-bound bifunctional proline racemase/hydroxyproline epimerase from a hyperthermophilic archaeon.
Biochem. Biophys. Res. Commun., 511, 2019
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2E0G
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6JNJ
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3WZU
 | | THE STRUCTURE OF MAP2K7 IN COMPLEX WITH 5Z-7-oxozeaenol | | 分子名称: | (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Dual specificity mitogen-activated protein kinase kinase 7 | | 著者 | Sogabe, Y, Hashimoto, Y, Matsumoto, T, Kinoshita, T. | | 登録日 | 2014-10-07 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | 5Z-7-Oxozeaenol covalently binds to MAP2K7 at Cys218 in an unprecedented manner.
Bioorg.Med.Chem.Lett., 25, 2015
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7VSX
 | | Crystal structure of QL-nanoKAZ (Reverse mutant of nanoKAZ with L18Q and V27L) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, QLnK | | 著者 | Tomabechi, Y, Sekine, S, Shirouzu, M, Takamitsu, H, Satoshi, I. | | 登録日 | 2021-10-27 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate.
Plos One, 17, 2022
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7BYU
 | | Crystal structure of Acidovorax avenae L-fucose mutarotase (apo form) | | 分子名称: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, L-fucose mutarotase | | 著者 | Watanabe, Y, Fukui, Y, Watanabe, S. | | 登録日 | 2020-04-24 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Functional and structural characterization of a novel L-fucose mutarotase involved in non-phosphorylative pathway of L-fucose metabolism.
Biochem.Biophys.Res.Commun., 528, 2020
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5H0B
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanoic acid | | 分子名称: | (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]azaniumyl]-4-methyl-pentanoate, Tyrosine-protein kinase HCK | | 著者 | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | | 登録日 | 2016-10-04 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Bioorg. Med. Chem., 25, 2017
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4YTV
 | | Crystal structure of Mdm35 | | 分子名称: | COBALT (II) ION, GLYCEROL, Mitochondrial distribution and morphology protein 35 | | 著者 | Watanabe, Y, Tamura, Y, Kawano, S, Endo, T. | | 登録日 | 2015-03-18 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and mechanistic insights into phospholipid transfer by Ups1-Mdm35 in mitochondria.
Nat Commun, 6, 2015
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5H0H
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-N,N,4-trimethylpentanamide | | 分子名称: | (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-~{N},~{N},4-trimethyl-pentanamide, Tyrosine-protein kinase HCK | | 著者 | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | | 登録日 | 2016-10-04 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Bioorg. Med. Chem., 25, 2017
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5H0E
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanamide | | 分子名称: | (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-4-methyl-pentanamide, Tyrosine-protein kinase HCK | | 著者 | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | | 登録日 | 2016-10-04 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Bioorg. Med. Chem., 25, 2017
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5H0G
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-N,4-dimethylpentanamide | | 分子名称: | (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-~{N},4-dimethyl-pentanamide, Tyrosine-protein kinase HCK | | 著者 | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | | 登録日 | 2016-10-04 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Bioorg. Med. Chem., 25, 2017
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6L06
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6L07
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4YTW
 | | Crystal structure of Ups1-Mdm35 complex | | 分子名称: | Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial | | 著者 | Watanabe, Y, Tamura, Y, Kawano, S, Endo, T. | | 登録日 | 2015-03-18 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural and mechanistic insights into phospholipid transfer by Ups1-Mdm35 in mitochondria.
Nat Commun, 6, 2015
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4YTX
 | | Crystal structure of Ups1-Mdm35 complex with PA | | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, Mitochondrial distribution and morphology protein 35, Protein UPS1, ... | | 著者 | Watanabe, Y, Tamura, Y, Kawano, S, Endo, T. | | 登録日 | 2015-03-18 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural and mechanistic insights into phospholipid transfer by Ups1-Mdm35 in mitochondria.
Nat Commun, 6, 2015
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5B2L
 | | A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Dual specificity mitogen-activated protein kinase kinase 7, GLYCEROL | | 著者 | Sogabe, Y, Hashimoto, T, Matsumoto, T, Kirii, Y, Sawa, M, Kinoshita, T. | | 登録日 | 2016-01-19 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7
Biochem.Biophys.Res.Commun., 473, 2016
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5H09
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-ethyl2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanoate | | 分子名称: | Tyrosine-protein kinase HCK, ethyl (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-4-methyl-pentanoate | | 著者 | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | | 登録日 | 2016-10-04 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | | 主引用文献 | Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Bioorg. Med. Chem., 25, 2017
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5B2K
 | | A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7 | | 分子名称: | Dual specificity mitogen-activated protein kinase kinase 7 | | 著者 | Sogabe, Y, Hashimoto, T, Matsumoto, T, Kirii, Y, Sawa, M, Kinoshita, T. | | 登録日 | 2016-01-19 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7
Biochem.Biophys.Res.Commun., 473, 2016
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