2Z3P
 
 | |
2Z3O
 | |
2Z3N
 | | complex structure of LF-transferase and peptide B | | Descriptor: | D(-)-TARTARIC ACID, Leucyl/phenylalanyl-tRNA-protein transferase, peptide (PHE)(ARG)(TYR)(LEU)(GLY) | | Authors: | Watanabe, K, Toh, Y, Tomita, K. | | Deposit date: | 2007-06-04 | | Release date: | 2007-10-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase
Nature, 449, 2007
|
|
3WZJ
 | | CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 4-(6-(cyclohexylamino)-8-(((tetrahydro-2H-pyran-4-yl)methyl)amino)imidazo[1,2-b]pyridazin-3-yl)-N-cyclopropylbenzamide | | Descriptor: | 4-{6-(cyclohexylamino)-8-[(tetrahydro-2H-pyran-4-ylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}-N-cyclopropylbenzamide, Dual specificity protein kinase TTK | | Authors: | Kusakabe, K, Ide, N, Daigo, Y, Itoh, T, Yamamoto, T, Kojima, E, Mitsuoka, Y, Tadano, G, Tagashira, S, Higashino, K, Okano, Y, Sato, Y, Inoue, M, Iguchi, M, Kanazawa, T, Ishioka, Y, Dohi, K, Kido, Y, Sakamoto, S, Ando, S, Maeda, M, Higaki, M, Yoshizawa, H, Mura, H, Nakamura, Y. | | Deposit date: | 2014-09-29 | | Release date: | 2015-02-11 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
J.Med.Chem., 58, 2015
|
|
3WYY
 | | CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH (E)-3-(4-((6-(((3s,5s,7s)-adamantan-1-yl)amino)-4-amino-5-cyanopyridin-2-yl)amino)-2-(cyanomethoxy)phenyl)-N-(2-methoxyethyl)acrylamide | | Descriptor: | (2E)-3-[4-({4-amino-5-cyano-6-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylamino]pyridin-2-yl}amino)-2-(cyanomethoxy)phenyl]-N-(2-methoxyethyl)prop-2-enamide, Dual specificity protein kinase TTK | | Authors: | Kusakabe, K, Ide, N, Daigo, Y, Itoh, T, Yamamoto, T, Kojima, E, Mitsuoka, Y, Tadano, G, Tagashira, S, Higashino, K, Okano, Y, Sato, Y, Inoue, M, Iguchi, M, Kanazawa, T, Ishioka, Y, Dohi, K, Kido, Y, Sakamoto, S, Ando, S, Maeda, M, Higaki, M, Yoshizawa, H, Murai, H, Nakamura, Y. | | Deposit date: | 2014-09-10 | | Release date: | 2015-04-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Bioorg.Med.Chem., 23, 2015
|
|
3S96
 | | Crystal structure of 3B5H10 | | Descriptor: | 3B5H10 FAB heavy chain, 3B5H10 FAB light chain | | Authors: | Weisgraber, K, Peters-Libeu, C, Rutenber, E, Newhouse, Y, Finkbeiner, S. | | Deposit date: | 2011-05-31 | | Release date: | 2012-02-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J.Mol.Biol., 421, 2012
|
|
2AF5
 | | 2.5A X-ray Structure of Engineered OspA protein | | Descriptor: | Engineered Outer Surface Protein A (OspA) with the inserted two beta-hairpins | | Authors: | Makabe, K, Mcelheny, D, Tereshko, V, Hilyard, A, Koide, A, Koide, S. | | Deposit date: | 2005-07-25 | | Release date: | 2006-08-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2G8C
 | |
2HKD
 | |
2I5V
 | | Crystal structure of OspA mutant | | Descriptor: | Outer surface protein A, TETRAETHYLENE GLYCOL | | Authors: | Makabe, K, Terechko, V, Koide, S. | | Deposit date: | 2006-08-25 | | Release date: | 2007-12-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | High-Resolution Structure of a Self-Assembly-Competent Form of a Hydrophobic Peptide Captured in a Soluble β-Sheet Scaffold.
J.Mol.Biol., 378, 2008
|
|
2FKJ
 | | The crystal structure of engineered OspA | | Descriptor: | Outer Surface Protein A | | Authors: | Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S. | | Deposit date: | 2006-01-04 | | Release date: | 2006-11-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2FKG
 | | The Crystal Structure of Engineered OspA | | Descriptor: | Outer Surface Protein A | | Authors: | Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S. | | Deposit date: | 2006-01-04 | | Release date: | 2006-11-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2I5Z
 | | The crystal structure of OspA mutant | | Descriptor: | Outer surface protein A, TETRAETHYLENE GLYCOL | | Authors: | Makabe, K, Terechko, V, Koide, S. | | Deposit date: | 2006-08-26 | | Release date: | 2007-07-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet.
J.Mol.Biol., 368, 2007
|
|
6J48
 | | Glycine mutation on single layer beta-sheet of OspAsm1 | | Descriptor: | Outer surface protein A, TETRAETHYLENE GLYCOL | | Authors: | Makabe, K, Hori, Y. | | Deposit date: | 2019-01-08 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.201 Å) | | Cite: | Grafting a short chameleon sequence from alpha B crystallin into a beta-sheet scaffold protein.
Proteins, 87, 2019
|
|
6J47
 | |
6J49
 | | Grafting VLADV sequence into OspAsm1 | | Descriptor: | Outer surface protein A, TETRAETHYLENE GLYCOL | | Authors: | Makabe, K, Hori, Y. | | Deposit date: | 2019-01-08 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Grafting a short chameleon sequence from alpha B crystallin into a beta-sheet scaffold protein.
Proteins, 87, 2019
|
|
2OL7
 | | The crystal structure of OspA mutant | | Descriptor: | Outer surface protein A | | Authors: | Makabe, K, Terechko, V, Koide, S. | | Deposit date: | 2007-01-18 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | beta-Strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of beta-Strand Pairing
J.Am.Chem.Soc., 129, 2007
|
|
2OL6
 | | The crystal structure of OspA mutant | | Descriptor: | Outer surface protein A | | Authors: | Makabe, K, Terechko, V, Koide, S. | | Deposit date: | 2007-01-18 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | beta-Strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of beta-Strand Pairing
J.Am.Chem.Soc., 129, 2007
|
|
2OL8
 | | The crystal structure of OspA mutant | | Descriptor: | Outer surface protein A | | Authors: | Makabe, K, Terechko, V, Koide, S. | | Deposit date: | 2007-01-18 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | beta-Strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of beta-Strand Pairing
J.Am.Chem.Soc., 129, 2007
|
|
2OY1
 | | The crystal structure of OspA mutant | | Descriptor: | Outer surface protein A | | Authors: | Makabe, K, Terechko, V, Koide, S. | | Deposit date: | 2007-02-21 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | beta-Strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of beta-Strand Pairing
J.Am.Chem.Soc., 129, 2007
|
|
2OY5
 | | The crystal structure of OspA mutant | | Descriptor: | Outer surface protein A | | Authors: | Makabe, K, Terechko, V, Biancalana, M, Yan, S, Koide, S. | | Deposit date: | 2007-02-21 | | Release date: | 2008-03-04 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Aromatic cluster mutations produce focal modulations of beta-sheet structure.
Protein Sci., 24, 2015
|
|
2OY8
 | |
2OY7
 | |
1EQK
 | | SOLUTION STRUCTURE OF ORYZACYSTATIN-I, A CYSTEINE PROTEINASE INHIBITOR OF THE RICE, ORYZA SATIVA L. JAPONICA | | Descriptor: | ORYZACYSTATIN-I | | Authors: | Nagata, K, Kudo, N, Abe, K, Arai, S, Tanokura, M. | | Deposit date: | 2000-04-05 | | Release date: | 2001-01-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure of oryzacystatin-I, a cysteine proteinase inhibitor of the rice, Oryza sativa L. japonica.
Biochemistry, 39, 2000
|
|
6DMS
 | | Endo-fucoidan hydrolase MfFcnA4_H294Q from glycoside hydrolase family 107 | | Descriptor: | 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION | | Authors: | Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B. | | Deposit date: | 2018-06-05 | | Release date: | 2018-10-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018
|
|
