8DXJ
 
 | | HIV-1 reverse transcriptase/rilpivirine with bound fragment 1-N-methyl-4-(trifluoromethyl)benzene-1,2-diamine at the NNRTI adjacent site | | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, DIMETHYL SULFOXIDE, ... | | 著者 | Chopra, A, Ruiz, F.X, Bauman, J.D, Arnold, E. | | 登録日 | 2022-08-02 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening.
J.Med.Chem., 66, 2023
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5G5E
 | | Crystallographic structure of the Tau class glutathione S-transferase MiGSTU from mango Mangifera indica L. | | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, TAU CLASS GLUTATHIONE S-TRANSFERASE | | 著者 | Valenzuela-Chavira, I, Serrano-Posada, H, Lopez-Zavala, A, Hernandez-Paredes, J, Sotelo-Mundo, R. | | 登録日 | 2016-05-24 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights Into Ligand Binding to a Glutathione S-Transferase from Mango: Structure, Thermodynamics and Kinetics
Biochimie, 135, 2017
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7NO8
 | | Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1"6 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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6SHZ
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7NOM
 | | Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Beta | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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8AGP
 | | Halogenated product of limonene epoxide turnover by epoxide hydrolase from metagenomic source ch65 | | 分子名称: | (1~{S},2~{S},4~{R})-2-chloranyl-1-methyl-4-prop-1-en-2-yl-cyclohexan-1-ol, 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, ... | | 著者 | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | | 登録日 | 2022-07-20 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Complexes of epoxide hydrolase from metagenomic source ch65
To Be Published
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6I5S
 | | AH, Bottromycin amidohydrolase | | 分子名称: | CHLORIDE ION, GLYCEROL, ZINC ION, ... | | 著者 | Koehnke, J, Sikandar, A. | | 登録日 | 2018-11-14 | | 公開日 | 2019-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Thiazoline-Specific Amidohydrolase PurAH Is the Gatekeeper of Bottromycin Biosynthesis.
J.Am.Chem.Soc., 141, 2019
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7NO1
 | | Structure of the mature RSV CA lattice: T=3 CA icosahedron | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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6SI4
 | | p53 cancer mutant Y220S in complex with small-molecule stabilizer PK9323 | | 分子名称: | 1-[9-ethyl-7-(1,3-thiazol-4-yl)carbazol-3-yl]-~{N}-methyl-methanamine, Cellular tumor antigen p53, GLYCEROL, ... | | 著者 | Joerger, A.C, Kraemer, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2019-08-08 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm.
Acs Chem.Biol., 15, 2020
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7NOE
 | | Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'5 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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5G5T
 | | Structure of the Argonaute protein from Methanocaldcoccus janaschii in complex with guide DNA | | 分子名称: | ARGONAUTE, GUIDE DNA, MAGNESIUM ION, ... | | 著者 | Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S. | | 登録日 | 2016-06-03 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
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7NO2
 | | Structure of the mature RSV CA lattice: hexamer derived from tubes (C2-symmetric) | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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7AWX
 | | Structure of the FKBP51FK1 domain in complex with the macrocyclic SAFit analogue 55 | | 分子名称: | Macrocyclic SAFit analogue 55, Peptidyl-prolyl cis-trans isomerase FKBP5 | | 著者 | Bauder, M, Meyners, C, Purder, P, Merz, S, Voll, A, Heymann, T, Hausch, F. | | 登録日 | 2020-11-09 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors.
J.Med.Chem., 64, 2021
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7NOD
 | | Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'4 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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7NOG
 | | Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 4'5 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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7NO9
 | | Structure of the mature RSV CA lattice: Group I, pentamer-pentamer interface, class 1'1 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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5G5I
 | | S. enterica HisA mutant D10G | | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHOSPHATE ION | | 著者 | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | | 登録日 | 2016-05-25 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6R6J
 | | Crystal structure of human carbonic anhydrase isozyme II with 2-(benzenesulfonyl)-4-chloro-N-(2-hydroxyethyl)-5-sulfamoyl-benzamide | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-chloranyl-~{N}-(2-hydroxyethyl)-2-(phenylsulfonyl)-5-sulfamoyl-benzamide, Carbonic anhydrase 2, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2019-03-27 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
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7NOO
 | | Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Alpha | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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7NOB
 | | Structure of the mature RSV CA lattice: Group II, hexamer-hexamer interface, class 2'6 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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7NO5
 | | Structure of the mature RSV CA lattice: hexamer with 2 adjacent pentamers (C2 symmetric) | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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6UWX
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7NOK
 | | Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 3'Gamma | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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5G5F
 | | Crystallographic structure of the Tau class glutathione S-transferase MiGSTU in complex with reduced glutathione. | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLUTATHIONE, TAU CLASS GLUTATHIONE S-TRANSFERASE | | 著者 | Valenzuela-Chavira, I, Serrano-Posada, H, Lopez-Zavala, A, Hernandez-Paredes, J, Sotelo-Mundo, R. | | 登録日 | 2016-05-24 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insights Into Ligand Binding to a Glutathione S-Transferase from Mango: Structure, Thermodynamics and Kinetics
Biochimie, 135, 2017
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7NO7
 | | Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1"2 | | 分子名称: | Capsid protein p27, alternate cleaved 1 | | 著者 | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
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