2WA5
 
 | | Crystal structure of human filamin B actin binding domain at 1.9 Angstroms resolution | | 分子名称: | CARBONATE ION, FILAMIN-B, SULFATE ION | | 著者 | Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J. | | 登録日 | 2009-02-03 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009
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6VXS
 | | Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 | | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Non-structural protein 3, ... | | 著者 | Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-02-24 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes.
Iucrj, 7, 2020
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6PLF
 | | Crystal structure of human PHGDH complexed with Compound 1 | | 分子名称: | 1,2-ETHANEDIOL, 4-{(1S)-1-[(5-chloro-6-{[(5S)-2-oxo-1,3-oxazolidin-5-yl]methoxy}-1H-indole-2-carbonyl)amino]-2-hydroxyethyl}benzoic acid, D-3-phosphoglycerate dehydrogenase | | 著者 | Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. | | 登録日 | 2019-06-30 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.
Bioorg.Med.Chem.Lett., 29, 2019
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6VVD
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4IBQ
 | | Human p53 core domain with hot spot mutation R273C | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... | | 著者 | Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. | | 登録日 | 2012-12-09 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.
Nucleic Acids Res., 41, 2013
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2WCJ
 | | Structure of BMori GOBP2 (General Odorant Binding Protein 2) with (10E,12Z)-tetradecadien-1-ol | | 分子名称: | (10E,12Z)-tetradeca-10,12-dien-1-ol, GENERAL ODORANT-BINDING PROTEIN 1, MAGNESIUM ION | | 著者 | Robertson, G, Zhou, J.-J, He, X, Pickett, J.A, Field, L.M, Keep, N.H. | | 登録日 | 2009-03-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Characterisation of Bombyx Mori Odorant-Binding Proteins Reveals that a General Odorant-Binding Protein Discriminates between Sex Pheromone Components.
J.Mol.Biol., 389, 2009
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5KEL
 | | EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ebola surface glycoprotein, ... | | 著者 | Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B. | | 登録日 | 2016-06-09 | | 公開日 | 2016-09-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
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3X0U
 | | Crystal structure of PirB | | 分子名称: | Uncharacterized protein | | 著者 | Wang, H.C, Ko, T.P, Wang, A.H.J, Lo, C.F. | | 登録日 | 2014-10-22 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2VSX
 | | Crystal Structure of a Translation Initiation Complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-DEPENDENT RNA HELICASE EIF4A, EUKARYOTIC INITIATION FACTOR 4F SUBUNIT P150 | | 著者 | Schutz, P, Bumann, M, Oberholzer, A.E, Bieniossek, C, Altmann, M, Trachsel, H, Baumann, U. | | 登録日 | 2008-04-30 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of the Yeast Eif4A-Eif4G Complex: An RNA-Helicase Controlled by Protein-Protein Interactions.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2W8X
 | | Structure of the tick ion-channel modulator Ra-KLP | | 分子名称: | ACETATE ION, GLYCEROL, IMIDAZOLE, ... | | 著者 | Paesen, G.C, Siebold, C, Dallas, M, Peers, C, Harlos, K, Nuttall, P.A, Nunn, M.A, Stuart, D.I, Esnouf, R.M. | | 登録日 | 2009-01-20 | | 公開日 | 2009-05-05 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An Ion-Channel Modulator from the Saliva of the Brown Ear Tick Has a Highly Modified Kunitz/Bpti Structure.
J.Mol.Biol., 389, 2009
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5DAZ
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4IDO
 | | human atlastin-1 1-446, C-his6, GDPAlF4- | | 分子名称: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | | 登録日 | 2012-12-12 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | | 主引用文献 | Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
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4IE9
 | | Bovine PKA C-alpha in complex with 3-pyridylmethyl-5-methyl-1H-pyrazole-3-carboxylate | | 分子名称: | GLYCEROL, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ... | | 著者 | Dreyer, M.K, Schiffer, A, Lodge, J. | | 登録日 | 2012-12-13 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
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2ISH
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7B5P
 | | AcrB in cycloalkane amphipol | | 分子名称: | Efflux pump membrane transporter | | 著者 | Higgins, A.J, Flynn, A.J, Muench, S.P. | | 登録日 | 2020-12-05 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis.
Commun Biol, 4, 2021
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1JLY
 | | CRYSTAL STRUCTURE OF AMARANTHUS CAUDATUS AGGLUTININ | | 分子名称: | AGGLUTININ | | 著者 | Transue, T.R, Smith, A.K, Mo, H, Goldstein, I.J, Saper, M.A. | | 登録日 | 1997-07-23 | | 公開日 | 1997-12-03 | | 最終更新日 | 2013-02-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.
Nat.Struct.Biol., 4, 1997
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4IEQ
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1JMP
 | | Solution Structure of the Viscotoxin B | | 分子名称: | viscotoxin B | | 著者 | Coulon, A, Mosbah, A, Bernard, C, Rouge, P, Urech, K, Darbon, H. | | 登録日 | 2001-07-19 | | 公開日 | 2003-11-11 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Comparative membrane interaction study of viscotoxins A3, A2 and B from mistletoe (Viscum album) and connections with their structures
Biochem.J., 374, 2003
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6W24
 | | ClpA Engaged2 State bound to RepA-GFP (Focused Classification) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | | 登録日 | 2020-03-04 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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5URT
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4IF5
 | | Structure of human Mec17 | | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, CHLORIDE ION | | 著者 | Davenport, A.M, Collins, L, Minor, P, Sternberg, P, Hoelz, A. | | 登録日 | 2012-12-14 | | 公開日 | 2014-05-28 | | 最終更新日 | 2014-07-02 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Characterization of the alpha-Tubulin Acetyltransferase MEC-17.
J.Mol.Biol., 426, 2014
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7ZS7
 | | Crystal structure of human cathepsin L with covalently bound calpain inhibitor VI | | 分子名称: | (2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxidanyl-pentan-2-yl]butanamide, ACETATE ION, Cathepsin L, ... | | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | | 登録日 | 2022-05-06 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors.
J.Med.Chem., 2024
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5K9G
 | | Crystal Structure of GTP Cyclohydrolase-IB with Tris | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, ... | | 著者 | Alvarez, J, Stec, B, Swairjo, M.A. | | 登録日 | 2016-05-31 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism and catalytic strategy of the prokaryotic-specific GTP cyclohydrolase-IB.
Biochem.J., 474, 2017
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4IGB
 | | Crystal structure of the N-terminal domain of the Streptococcus gordonii adhesin Sgo0707 | | 分子名称: | ACETATE ION, GLYCEROL, LPXTG cell wall surface protein, ... | | 著者 | Nylander, A, Svensater, G, Senadheera, D.B, Cvitkovitch, D.G, Davies, J.R, Persson, K. | | 登録日 | 2012-12-17 | | 公開日 | 2013-06-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural and Functional Analysis of the N-terminal Domain of the Streptococcus gordonii Adhesin Sgo0707
Plos One, 8, 2013
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5UVE
 | | Crystal Structure of the ABC Transporter Substrate-binding protein BAB1_0226 from Brucella abortus | | 分子名称: | CALCIUM ION, GLYCEROL, Substrate-binding region of ABC-type glycine betaine transport system | | 著者 | Kim, Y, Chhor, G, Endres, M, Hero, J, Babnigg, G, Crosson, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2017-02-20 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Beta-barrel-like Protein of Unknown Function
To Be Published
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