6XBB
 
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6XRE
 | | Structure of the p53/RNA polymerase II assembly | | 分子名称: | Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. | | 登録日 | 2020-07-12 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structure of the p53/RNA polymerase II assembly.
Commun Biol, 4, 2021
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8C0N
 | | Crystal structure of the red form of the mTagFT fluorescent timer | | 分子名称: | Blue-to-red TagFT fluorescent timer | | 著者 | Boyko, K.M, Nikolaeva, A.Y, Vlaskina, A.V, Agapova, Y.K, Subach, O.M, Popov, V.O, Subach, F.V. | | 登録日 | 2022-12-19 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Blue-to-Red TagFT, mTagFT, mTsFT, and Green-to-FarRed mNeptusFT2 Proteins, Genetically Encoded True and Tandem Fluorescent Timers.
Int J Mol Sci, 24, 2023
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8ESC
 | | Structure of the Yeast NuA4 Histone Acetyltransferase Complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | | 著者 | Patel, A.B, Zukin, S.A, Nogales, E. | | 登録日 | 2022-10-13 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
Elife, 11, 2022
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6URK
 | | Barrier-to-autointegration factor soaked in Glycerol: 1 of 14 in MSCS set | | 分子名称: | Barrier-to-autointegration factor, ETHANOL | | 著者 | Agarwal, S, Smith, M, De La Rosa, I, Kliment, A.V, Swartz, P, Segura-Totten, M, Mattos, C. | | 登録日 | 2019-10-23 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor.
Acta Crystallogr D Struct Biol, 76, 2020
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5M14
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5JBI
 | | Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC52 and manganese | | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... | | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | | 登録日 | 2016-04-13 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin.
Chemmedchem, 11, 2016
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6S0L
 | | Structure of the A2A adenosine receptor determined at SwissFEL using native-SAD at 4.57 keV from all available diffraction patterns | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ... | | 著者 | Nass, K, Cheng, R, Vera, L, Mozzanica, A, Redford, S, Ozerov, D, Basu, S, James, D, Knopp, G, Cirelli, C, Martiel, I, Casadei, C, Weinert, T, Nogly, P, Skopintsev, P, Usov, I, Leonarski, F, Geng, T, Rappas, M, Dore, A.S, Cooke, R, Nasrollahi Shirazi, S, Dworkowski, F, Sharpe, M, Olieric, N, Steinmetz, M.O, Schertler, G, Abela, R, Patthey, L, Schmitt, B, Hennig, M, Standfuss, J, Wang, M, Milne, J.C. | | 登録日 | 2019-06-17 | | 公開日 | 2020-07-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Advances in long-wavelength native phasing at X-ray free-electron lasers.
Iucrj, 7, 2020
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8F21
 | | Structure of a 30mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (14.1 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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7AQB
 | | Crystal structure of human mitogen activated protein kinase 6 (MAPK6) | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Mitogen-activated protein kinase 6 | | 著者 | Filippakopoulos, P, Schroeder, M, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-10-20 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3.
Int J Mol Sci, 21, 2020
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5M30
 | | Structure of TssK from T6SS EAEC in complex with nanobody nb18 | | 分子名称: | Anti-vesicular stomatitis virus N VHH, Type VI secretion protein | | 著者 | Nguyen, V.S, Cambillau, C, Spinelli, C, Desmyter, A, Legrand, P, Cascales, E. | | 登録日 | 2016-10-13 | | 公開日 | 2017-06-21 | | 最終更新日 | 2017-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
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6EXL
 | | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - folded HTH motif | | 分子名称: | ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, SODIUM ION, ... | | 著者 | Hall, M, Grundstrom, C, Begum, A, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. | | 登録日 | 2017-11-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
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6OCL
 | | Crystal Structure of Leporine Serum Albumin in Complex with Suprofen | | 分子名称: | (2S)-2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid, ACETATE ION, Serum albumin, ... | | 著者 | Zielinski, K, Sekula, B, Bujacz, A, Bujacz, G. | | 登録日 | 2019-03-24 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural investigations of stereoselective profen binding by equine and leporine serum albumins.
Chirality, 32, 2020
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8CK0
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5JCG
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5IUM
 | | Crystal structure of phosphorylated DesKC | | 分子名称: | GLYCEROL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Trajtenberg, F, Buschiazzo, A. | | 登録日 | 2016-03-18 | | 公開日 | 2016-12-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.162 Å) | | 主引用文献 | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
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8F1U
 | | Structure of a 24mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (13.8 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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7YEB
 | | TR-SFX MmCPDII-DNA complex: 3.35 ns snapshot. Includes 3.35 ns, dark, and extrapolated structure factors | | 分子名称: | CPD photolesion containing DNA, CPD photolesion containing DNA after repair, Deoxyribodipyrimidine photolyase, ... | | 著者 | Maestre-Reyna, M, Wang, P.-H, Nango, E, Hosokawa, Y, Saft, M, Furrer, A, Yang, C.-H, Ngura Putu, E.P.G, Wu, W.-J, Emmerich, H.-J, Engilberge, S, Caramello, N, Wranik, M, Glover, H.L, Franz-Badur, S, Wu, H.-Y, Lee, C.-C, Huang, W.-C, Huang, K.-F, Chang, Y.-K, Liao, J.-H, Weng, J.-H, Gad, W, Chang, C.-W, Pang, A.H, Gashi, D, Beale, E, Ozerov, D, Milne, C, Cirelli, C, Bacellar, C, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Spadaccini, R, Royant, A, Yamamoto, J, Iwata, S, Standfuss, J, Essen, L.-O, Bessho, Y, Tsai, M.-D. | | 登録日 | 2022-07-05 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Visualizing the DNA repair process by a photolyase at atomic resolution.
Science, 382, 2023
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6OXM
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7YEI
 | | TR-SFX MmCPDII-DNA complex: 10 ns time-point collected in SACLA. Includes 10 ns, dark, and extrapolated structure factors | | 分子名称: | CPD photolesion containing DNA after repair, Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Maestre-Reyna, M, Wang, P.-H, Nango, E, Hosokawa, Y, Saft, M, Furrer, A, Yang, C.-H, Ngura Putu, E.P.G, Wu, W.-J, Emmerich, H.-J, Engilberge, S, Caramello, N, Wranik, M, Glover, H.L, Franz-Badur, S, Wu, H.-Y, Lee, C.-C, Huang, W.-C, Huang, K.-F, Chang, Y.-K, Liao, J.-H, Weng, J.-H, Gad, W, Chang, C.-W, Pang, A.H, Gashi, D, Beale, E, Ozerov, D, Milne, C, Cirelli, C, Bacellar, C, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Spadaccini, R, Royant, A, Yamamoto, J, Iwata, S, Standfuss, J, Essen, L.-O, Bessho, Y, Tsai, M.-D. | | 登録日 | 2022-07-05 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Visualizing the DNA repair process by a photolyase at atomic resolution.
Science, 382, 2023
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8GKF
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5LE4
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_11_D12 | | 分子名称: | DD_D12_11_D12 | | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | 登録日 | 2016-06-29 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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7YEC
 | | TR-SFX MmCPDII-DNA complex: 6 ns snapshot. Includes 6 ns, dark, and extrapolated structure factors | | 分子名称: | CPD photolesion containing DNA, Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Maestre-Reyna, M, Wang, P.-H, Nango, E, Hosokawa, Y, Saft, M, Furrer, A, Yang, C.-H, Ngura Putu, E.P.G, Wu, W.-J, Emmerich, H.-J, Engilberge, S, Caramello, N, Wranik, M, Glover, H.L, Franz-Badur, S, Wu, H.-Y, Lee, C.-C, Huang, W.-C, Huang, K.-F, Chang, Y.-K, Liao, J.-H, Weng, J.-H, Gad, W, Chang, C.-W, Pang, A.H, Gashi, D, Beale, E, Ozerov, D, Milne, C, Cirelli, C, Bacellar, C, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Spadaccini, R, Royant, A, Yamamoto, J, Iwata, S, Standfuss, J, Essen, L.-O, Bessho, Y, Tsai, M.-D. | | 登録日 | 2022-07-05 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Visualizing the DNA repair process by a photolyase at atomic resolution.
Science, 382, 2023
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5LEA
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_12_3G124 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DD_Off7_12_3G124 | | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | 登録日 | 2016-06-29 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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7Q51
 | | yeast Gid10 bound to a Phe/N-peptide | | 分子名称: | CHLORIDE ION, FWLPANLW peptide, Uncharacterized protein YGR066C | | 著者 | Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2021-11-02 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
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