4M75
 
 | | Crystal structure of Lsm1-7 complex | | Descriptor: | CHLORIDE ION, U6 snRNA-associated Sm-like protein Lsm1, U6 snRNA-associated Sm-like protein Lsm2, ... | | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | | Deposit date: | 2013-08-12 | | Release date: | 2013-10-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
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4M78
 | | Crystal structure of Lsm2-8 complex, space group P21 | | Descriptor: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | | Deposit date: | 2013-08-12 | | Release date: | 2013-11-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.794 Å) | | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
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4M7D
 | | Crystal structure of Lsm2-8 complex bound to the RNA fragment CGUUU | | Descriptor: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | | Deposit date: | 2013-08-12 | | Release date: | 2013-11-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.595 Å) | | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
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4M77
 | | Crystal structure of Lsm2-8 complex, space group I212121 | | Descriptor: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | | Deposit date: | 2013-08-12 | | Release date: | 2013-11-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.111 Å) | | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
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4M7A
 | | Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA | | Descriptor: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | | Deposit date: | 2013-08-12 | | Release date: | 2013-11-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.781 Å) | | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
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5Y62
 | | YfiR complexed with GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, YfiR | | Authors: | Zhou, L, Xu, M, Jiang, T. | | Deposit date: | 2017-08-10 | | Release date: | 2017-09-20 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
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6QUM
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6R10
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6R0W
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6R0Z
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6R0Y
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4FZP
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1M0E
 | | ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE | | Descriptor: | 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ... | | Authors: | Zhou, L, Cheng, X, Connolly, B.A, Dickman, M.J, Hurd, P.J, Hornby, D.P. | | Deposit date: | 2002-06-12 | | Release date: | 2002-09-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
J.MOL.BIOL., 321, 2002
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7TGH
 | | Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... | | Authors: | Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A. | | Deposit date: | 2022-01-07 | | Release date: | 2022-04-06 | | Last modified: | 2024-12-25 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
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5EIV
 | | Crystal structure of complex of osteoclast-associated immunoglobulin-like receptor (OSCAR) and a synthetic collagen consensus peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | | Authors: | Zhou, L, Blaszczyk, M, Chirgadze, D, Bihan, D, Farndale, R.W. | | Deposit date: | 2015-10-30 | | Release date: | 2015-11-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.414 Å) | | Cite: | Structural basis for collagen recognition by the immune receptor OSCAR.
Blood, 127, 2016
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5Y64
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5Y61
 | | YfiB-YfiR complexed with GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, YfiB, YfiR | | Authors: | Zhou, L, Xu, M, Jiang, T. | | Deposit date: | 2017-08-10 | | Release date: | 2017-09-20 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
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8WB1
 | | Crystal Structure of small molecule KN2H covalently bound to K-Ras(G12D) | | Descriptor: | 1,2-ETHANEDIOL, 1-[(1~{S},5~{R})-3-[7-(8-ethynyl-7-fluoranyl-3-oxidanyl-naphthalen-1-yl)-8-fluoranyl-2-[[(2~{R},8~{S})-2-fluoranyl-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]ethanone, GTPase KRas, ... | | Authors: | Zhou, L, Zhang, R, Shuai, T.B. | | Deposit date: | 2023-09-08 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Crystal Structure of small molecule KN2H covalently bound to K-Ras(G12D)
To Be Published
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8ITD
 | | Phosphoglycerate mutase 1 complexed with a compound | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(4-chloranyl-2-oxidanyl-phenyl)-2-[(4-phenylphenyl)sulfonylamino]benzoic acid, CHLORIDE ION, ... | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a compound
To Be Published
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8IT7
 | | Phosphoglycerate mutase 1 complexed with a compound | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(4-chlorophenyl)-2-oxidanyl-6-[(4-phenylphenyl)sulfonylamino]benzoic acid, CHLORIDE ION, ... | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a compound
To Be Published
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8IT8
 | | Phosphoglycerate mutase 1 complexed with a compound | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(4-chlorophenyl)-2-[(4-phenylphenyl)sulfonylamino]benzoic acid, CHLORIDE ION, ... | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a compound
To Be Published
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8IT4
 | | Phosphoglycerate mutase 1 complexed with a covalent inhibitor | | Descriptor: | 3-[[5-(4-chlorophenyl)-2-methoxycarbonyl-thiophen-3-yl]sulfamoyl]benzenesulfonic acid, CHLORIDE ION, Phosphoglycerate mutase 1 | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a covalent inhibitor
To Be Published
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8IT6
 | | Phosphoglycerate mutase 1 complexed with a compound | | Descriptor: | 4-[4-chloranyl-2-(2-hydroxy-2-oxoethyloxy)phenyl]-2-[(4-phenylphenyl)sulfonylamino]benzoic acid, CHLORIDE ION, Phosphoglycerate mutase 1 | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a compound
To Be Published
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8ITC
 | | Phosphoglycerate mutase 1 complexed with a compound | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-(4-chlorophenyl)-3-[(4-phenylphenyl)sulfonylamino]phthalic acid, CHLORIDE ION, ... | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a compound
To Be Published
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8ITB
 | | Phosphoglycerate mutase 1 complexed with a compound | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-(3-chloranyl-4-fluoranyl-phenyl)-2-oxidanyl-3-[(4-phenylphenyl)sulfonylamino]benzoic acid, CHLORIDE ION, ... | | Authors: | Zhou, L, Jiang, L.L. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Phosphoglycerate mutase 1 complexed with a compound
To Be Published
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