4PIF
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4PIU
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8HGK
| Crystal structure of human ClpP in complex with ZK53 | Descriptor: | 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... | Authors: | Yang, C.-G, Gan, J.H, Zhou, L.-L. | Deposit date: | 2022-11-14 | Release date: | 2023-09-27 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma. Nat Commun, 14, 2023
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4XOK
| Observing the overall rocking motion of a protein in a crystal. | Descriptor: | Ubiquitin, ZINC ION | Authors: | Coquelle, N, Ma, P, Schanda, P, Colletier, J.P. | Deposit date: | 2015-01-16 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Observing the overall rocking motion of a protein in a crystal. Nat Commun, 6, 2015
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4XOL
| Observing the overall rocking motion of a protein in a crystal - Cubic Ubiquitin crystals. | Descriptor: | Ubiquitin, ZINC ION | Authors: | Coquelle, N, Peixiang, M, Schanda, P, Colletier, J.P. | Deposit date: | 2015-01-16 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Observing the overall rocking motion of a protein in a crystal. Nat Commun, 6, 2015
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4XOF
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7XKS
| Crystal structure of an alkaline pectate lyase from Bacillus clausii | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Pectate lyase | Authors: | Zhou, C, Zheng, Y.Y, Liu, W.D, Ma, Y. | Deposit date: | 2022-04-20 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of an Alkaline Pectate Lyase and Rational Engineering with Improved Thermo-Alkaline Stability for Efficient Ramie Degumming. Int J Mol Sci, 24, 2022
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2JFW
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2JFO
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2JFN
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2JFU
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2JFP
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2JFQ
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2JFV
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2JFZ
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2JFY
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4YKN
| Pi3K alpha lipid kinase with Active Site Inhibitor | Descriptor: | 3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid, Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform fusion protein | Authors: | Elkins, P.A. | Deposit date: | 2015-03-04 | Release date: | 2015-06-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Discovery of a Potent Class of PI3K alpha Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT). Acs Med.Chem.Lett., 6, 2015
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5CSM
| YEAST CHORISMATE MUTASE, T226S MUTANT, COMPLEX WITH TRP | Descriptor: | CHORISMATE MUTASE, TRYPTOPHAN | Authors: | Straeter, N, Schnappauf, G, Braus, G, Lipscomb, W.N. | Deposit date: | 1997-07-14 | Release date: | 1998-01-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures. Structure, 5, 1997
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5DDP
| L-glutamine riboswitch bound with L-glutamine | Descriptor: | GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... | Authors: | Ren, A, Patel, D.J. | Deposit date: | 2015-08-25 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
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5DDO
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5DDQ
| L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ | Descriptor: | GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... | Authors: | Ren, A, Patel, D.J. | Deposit date: | 2015-08-25 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
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5DDR
| L-glutamine riboswitch bound with L-glutamine soaked with Cs+ | Descriptor: | CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ... | Authors: | Ren, A, Patel, D.J. | Deposit date: | 2015-08-25 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
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6AGH
| Crystal structure of EFHA1 in Apo-State | Descriptor: | Calcium uptake protein 2, mitochondrial | Authors: | Yangfei, X, Xue, Y, Yuequan, S. | Deposit date: | 2018-08-11 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.742 Å) | Cite: | Dimerization of MICU Proteins Controls Ca2+Influx through the Mitochondrial Ca2+Uniporter. Cell Rep, 26, 2019
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6AGJ
| Crystal Structure of EFHA2 in Apo State | Descriptor: | Calcium uptake protein 3, mitochondrial | Authors: | Yangfei, X, Xue, Y, Yuequan, S. | Deposit date: | 2018-08-11 | Release date: | 2019-01-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.999 Å) | Cite: | Dimerization of MICU Proteins Controls Ca2+Influx through the Mitochondrial Ca2+Uniporter. Cell Rep, 26, 2019
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6AGI
| Crystal Structure of EFHA2 in Ca-binding State | Descriptor: | CALCIUM ION, Calcium uptake protein 3, mitochondrial, ... | Authors: | Yangfei, X, Xue, Y, Yuequan, S. | Deposit date: | 2018-08-11 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.799 Å) | Cite: | Dimerization of MICU Proteins Controls Ca2+Influx through the Mitochondrial Ca2+Uniporter. Cell Rep, 26, 2019
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