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5TWF
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BU of 5twf by Molmil
Regulation of protein interactions by MOB1 phosphorylation
分子名称: MOB kinase activator 1A, ZINC ION
著者Xiong, S, Sicheri, F.
登録日2016-11-13
公開日2017-04-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.136 Å)
主引用文献Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.
Mol. Cell Proteomics, 16, 2017
6BXI
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BU of 6bxi by Molmil
X-ray crystal structure of NDR1 kinase domain
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase 38
著者Xiong, S, Sicheri, F.
登録日2017-12-18
公開日2018-08-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.
Structure, 26, 2018
5TWH
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BU of 5twh by Molmil
human MOB1A bound to MST1 phosphorylated T367 peptide
分子名称: MOB kinase activator 1A, T367 peptide, ZINC ION
著者Xiong, S, Sicheri, F.
登録日2016-11-13
公開日2017-04-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol. Cell Proteomics, 16, 2017
5TWG
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BU of 5twg by Molmil
human MOB1A bound to human MST1 phosphorylated T353 peptide
分子名称: MOB kinase activator 1A, T353 peptide, ZINC ION
著者Xiong, S, Sicheri, F.
登録日2016-11-13
公開日2017-04-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol. Cell Proteomics, 16, 2017
2DK9
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BU of 2dk9 by Molmil
Solution structure of Calponin Homology domain of Human MICAL-1
分子名称: NEDD9-interacting protein with calponin homology and LIM domains
著者Sun, H, Dai, H, Zhang, J, Xiong, S, Wu, J, Shi, Y.
登録日2006-04-07
公開日2006-09-19
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of calponin homology domain of Human MICAL-1
J.Biomol.Nmr, 36, 2006
7DD1
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BU of 7dd1 by Molmil
Crystal structure of SRPK1 in complex with a peptide inhibitor
分子名称: ARG-GLU-ARG-ALA-ARG-THR-ARG, SRSF protein kinase 1,SRSF protein kinase 1
著者Li, Q.Y, Yung, K.W.Y, Ngo, J.C.K.
登録日2020-10-27
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Protein-Protein Interaction Inhibitor of SRPKs Alters the Splicing Isoforms of VEGF and Inhibits Angiogenesis.
Iscience, 24, 2021
7WNV
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BU of 7wnv by Molmil
Crystal structure of mutant estrogen receptor alpha Y537S in complex with CO9
分子名称: (~{Z})-4-[2-[4-[[2-(4-hydroxyphenyl)-6-oxidanyl-1-benzothiophen-3-yl]oxy]phenoxy]ethylamino]-~{N},~{N}-dimethyl-but-2-enamide, Estrogen receptor
著者Xiao, Y, Lv, Y.
登録日2022-01-19
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles.
Bioorg.Chem., 141, 2023

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件を2024-04-24に公開中

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