1G6V
| Complex of the camelid heavy-chain antibody fragment CAB-CA05 with bovine carbonic anhydrase | Descriptor: | ANTIBODY HEAVY CHAIN, CARBONIC ANHYDRASE, ZINC ION | Authors: | Desmyter, A, Decanniere, K, Muyldermans, S, Wyns, L. | Deposit date: | 2000-11-08 | Release date: | 2000-11-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody. J.Biol.Chem., 276, 2001
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1GSP
| RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY | Descriptor: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, RIBONUCLEASE T1 | Authors: | Zegers, I, Wyns, L. | Deposit date: | 1997-11-28 | Release date: | 1998-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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2GSP
| RIBONUCLEASE T1/2',3'-CGPS AND 3'-GMP, 2 DAYS | Descriptor: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ... | Authors: | Zegers, I, Wyns, L. | Deposit date: | 1997-12-02 | Release date: | 1998-08-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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1JF8
| X-ray structure of reduced C10S, C15A arsenate reductase from pI258 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICARBONATE ION, POTASSIUM ION, ... | Authors: | Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. | Deposit date: | 2001-06-20 | Release date: | 2001-10-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty. Nat.Struct.Biol., 8, 2001
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1JFV
| X-Ray Structure of oxidised C10S, C15A arsenate reductase from pI258 | Descriptor: | PERCHLORATE ION, POTASSIUM ION, arsenate reductase | Authors: | Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. | Deposit date: | 2001-06-22 | Release date: | 2001-10-03 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty. Nat.Struct.Biol., 8, 2001
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1LK0
| Disulfide intermediate of C89L Arsenate reductase from pI258 | Descriptor: | CHLORIDE ION, POTASSIUM ION, arsenate reductase | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | Deposit date: | 2002-04-23 | Release date: | 2002-08-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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1LU2
| DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE BLOOD GROUP A TRISACCHARIDE | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, LECTIN, ... | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. | Deposit date: | 1998-07-30 | Release date: | 1998-12-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus. J.Mol.Biol., 286, 1999
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1LJL
| Wild Type pI258 S. aureus arsenate reductase | Descriptor: | POTASSIUM ION, arsenate reductase | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | Deposit date: | 2002-04-21 | Release date: | 2002-08-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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1LU1
| THE STRUCTURE OF THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE FORSSMAN DISACCHARIDE | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ADENINE, CALCIUM ION, ... | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. | Deposit date: | 1998-07-24 | Release date: | 1998-12-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus. J.Mol.Biol., 286, 1999
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1LJU
| X-RAY STRUCTURE OF C15A ARSENATE REDUCTASE FROM PI258 COMPLEXED WITH ARSENITE | Descriptor: | POTASSIUM ION, arsenate reductase | Authors: | Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. | Deposit date: | 2002-04-22 | Release date: | 2002-08-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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1MEL
| CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME | Descriptor: | LYSOZYME, VH SINGLE-DOMAIN ANTIBODY | Authors: | Desmyter, A, Transue, T.R, Arbabi Gharoudi, M, Dao Thi, M, Poortmans, F, Hamers, R, Muyldermans, S, Wyns, L. | Deposit date: | 1996-06-06 | Release date: | 1997-06-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme. Nat.Struct.Biol., 3, 1996
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1ZMY
| cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme | Descriptor: | Antibody cabbcII-10:lys3, Lysozyme C | Authors: | Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K. | Deposit date: | 2005-05-11 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies J.Mol.Biol., 352, 2005
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1YVS
| Trimeric domain swapped barnase | Descriptor: | BARNASE, SULFATE ION | Authors: | Zegers, I, Wyns, L. | Deposit date: | 1998-12-10 | Release date: | 1999-02-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Trimeric domain-swapped barnase. Proc.Natl.Acad.Sci.USA, 96, 1999
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1ZV5
| Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme | Descriptor: | Lysozyme C, PHOSPHATE ION, immunoglobulin heavy chain antibody variable domain | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | Deposit date: | 2005-06-01 | Release date: | 2006-04-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVH
| Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme | Descriptor: | Immunoglobulin heavy chain antibody variable domain, Lysozyme C | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | Deposit date: | 2005-06-02 | Release date: | 2006-04-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVY
| Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme | Descriptor: | GLYCEROL, Immunoglobulin heavy chain antibody variable domain, Lysozyme C, ... | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | Deposit date: | 2005-06-03 | Release date: | 2006-04-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1N3Q
| Pterocarpus angolensis lectin complexed with turanose | Descriptor: | CALCIUM ION, MANGANESE (II) ION, alpha-D-glucopyranose-(1-3)-beta-D-fructofuranose, ... | Authors: | Loris, R, Imberty, A, Beeckmans, S, Van Driessche, E, Read, J.S, Bouckaert, J, De Greve, H, Buts, L, Wyns, L. | Deposit date: | 2002-10-29 | Release date: | 2002-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose J.BIOL.CHEM., 278, 2003
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1N3O
| Pterocarcpus angolensis lectin in complex with alpha-methyl glucose | Descriptor: | CALCIUM ION, MANGANESE (II) ION, lectin PAL, ... | Authors: | Loris, R, Imberty, A, Beeckmans, S, Van Driessche, E, Read, J.S, Bouckaert, J, De Greve, H, Buts, L, Wyns, L. | Deposit date: | 2002-10-29 | Release date: | 2002-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose J.BIOL.CHEM., 278, 2003
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1N3P
| Pterocarpus angolensis lectin in complex with sucrose | Descriptor: | CALCIUM ION, MANGANESE (II) ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | Authors: | Loris, R, Imberty, A, Beeckmans, S, Van Driessche, E, Read, J.S, Bouckaert, J, De Greve, H, Buts, L, Wyns, L. | Deposit date: | 2002-10-29 | Release date: | 2002-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose J.BIOL.CHEM., 278, 2003
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1ONA
| CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE | Descriptor: | CALCIUM ION, CONCANAVALIN A, MANGANESE (II) ION, ... | Authors: | Bouckaert, J, Maes, D, Poortmans, F, Wyns, L, Loris, R. | Deposit date: | 1996-07-07 | Release date: | 1997-09-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A structure of the complex between concanavalin A and methyl-3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside reveals two binding modes. J.Biol.Chem., 271, 1996
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1QDC
| MAN(APLHA1-6)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX | Descriptor: | CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Bouckaert, J, Loris, R, Wyns, L. | Deposit date: | 1998-07-14 | Release date: | 1999-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A. J.Biol.Chem., 274, 1999
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1QDO
| MAN(APLHA1-3)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX | Descriptor: | CALCIUM ION, MANGANESE (II) ION, PROTEIN (CONCANAVALIN A), ... | Authors: | Bouckaert, J, Loris, R, Wyns, L. | Deposit date: | 1999-05-24 | Release date: | 1999-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A. J.Biol.Chem., 274, 1999
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1MVF
| MazE addiction antidote | Descriptor: | PemI-like protein 1, immunoglobulin heavy chain variable region | Authors: | Loris, R, Marianovsky, I, Lah, J, Laeremans, T, Engelberg-Kulka, H, Glaser, G, Muyldermans, S, Wyns, L. | Deposit date: | 2002-09-25 | Release date: | 2003-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of the intrinsically flexible addiction antidote MazE. J.Biol.Chem., 278, 2003
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1OUS
| Lecb (PA-LII) calcium-free | Descriptor: | SULFATE ION, hypothetical protein LecB | Authors: | Loris, R, Tielker, D, Jaeger, K.-E, Wyns, L. | Deposit date: | 2003-03-25 | Release date: | 2003-09-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Basis of Carbohydrate Recognition by the Lectin LecB from Pseudomonas aeruginosa J.MOL.BIOL., 331, 2003
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1OVS
| LecB (PA-LII) in complex with core trimannoside | Descriptor: | CALCIUM ION, alpha-D-mannopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, ... | Authors: | Loris, R, Tielker, D, Jaeger, K.-E, Wyns, L. | Deposit date: | 2003-03-27 | Release date: | 2003-09-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis of Carbohydrate Recognition by the Lectin LecB from Pseudomonas aeruginosa J.MOL.BIOL., 331, 2003
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