4RVI
 
 | | Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL0519 | | Descriptor: | (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, HIV-1 protease | | Authors: | Yedidi, R.S, Garimella, H, Kaufman, J.D, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | | Deposit date: | 2014-11-26 | | Release date: | 2016-05-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Enhanced antiviral activity by the P2-tris-tetrahydrofuran moiety of GRL-0519, a novel nonpeptidic HIV-1 protease inhibitor (PI), against multi-PI-resistant and highly darunavir-resistant strains of HIV-1
To be Published
|
|
4RVX
 | | Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL079 | | Descriptor: | (4S)-4-amino-N-[(2S,3S)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]-3,4-dihydro-2H-chromene-6-carboxamide, HIV-1 Protease | | Authors: | Yedidi, R.S, Garimella, H, Kaufman, J.D, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | | Deposit date: | 2014-11-28 | | Release date: | 2016-05-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.955 Å) | | Cite: | Enhanced antiviral activity by the P2-tris-tetrahydrofuran moiety of GRL-0519, a novel nonpeptidic HIV-1 protease inhibitor (PI), against multi-PI-resistant and highly darunavir-resistant strains of HIV-1.
To be Published
|
|
3V6F
 | | Crystal Structure of an anti-HBV e-antigen monoclonal Fab fragment (e6), unbound | | Descriptor: | Fab e6 Heavy Chain, Fab e6 Light Chain | | Authors: | Dimattia, M.A, Watts, N.R, Stahl, S.J, Grimes, J.M, Steven, A.C, Stuart, D.I, Wingfield, P.T. | | Deposit date: | 2011-12-19 | | Release date: | 2013-02-06 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein.
Structure, 21, 2013
|
|
3V6Z
 | | Crystal Structure of Hepatitis B Virus e-antigen | | Descriptor: | Fab e6 Heavy Chain, Fab e6 Light Chain, e-antigen | | Authors: | Dimattia, M.A, Watts, N.R, Stahl, S.J, Grimes, J.M, Steven, A.C, Stuart, D.I, Wingfield, P.T. | | Deposit date: | 2011-12-20 | | Release date: | 2013-02-06 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (3.34 Å) | | Cite: | Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein.
Structure, 21, 2013
|
|
6I1B
 | |
7I1B
 | |
7U0F
 | | HIV-1 Rev in complex with tubulin | | Descriptor: | Protein Rev, Tubulin alpha-1A chain, Tubulin beta chain | | Authors: | Eren, E. | | Deposit date: | 2022-02-18 | | Release date: | 2023-08-23 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
Structure, 31, 2023
|
|
2JR0
 | | Solution structure of NusB from Aquifex Aeolicus | | Descriptor: | N utilization substance protein B homolog | | Authors: | Das, R, Loss, S, Li, J, Tarasov, S, Wingfield, P, Waugh, D.S, Byrd, R.A, Altieri, A.S. | | Deposit date: | 2007-06-18 | | Release date: | 2008-02-19 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural biophysics of the NusB:NusE antitermination complex.
J.Mol.Biol., 376, 2008
|
|
4TRX
 | |
7M18
 | | HeLa-tubulin in complex with cryptophycin 1 | | Descriptor: | Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Eren, E. | | Deposit date: | 2021-03-12 | | Release date: | 2021-09-08 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
|
|
7M20
 | | 18-mer HeLa-tubulin rings in complex with Cryptophycin 1 | | Descriptor: | Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Eren, E. | | Deposit date: | 2021-03-15 | | Release date: | 2021-09-08 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
|
|
7LXB
 | | HeLa-tubulin in complex with cryptophycin 52 | | Descriptor: | Cryptophycin 52, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Eren, E. | | Deposit date: | 2021-03-03 | | Release date: | 2021-09-08 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
|
|
2EZP
 | |
2EZS
 | |
2EZR
 | |
2EZO
 | |
2EZQ
 | |
3TRX
 | |
2NVH
 | |
1D8V
 | | THE RESTRAINED AND MINIMIZED AVERAGE NMR STRUCTURE OF MAP30. | | Descriptor: | ANTI-HIV AND ANTI-TUMOR PROTEIN MAP30 | | Authors: | Wang, Y.-X, Neamati, N, Jacob, J, Palmer, I, Stahl, S.J. | | Deposit date: | 1999-10-26 | | Release date: | 1999-11-19 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions.
Cell(Cambridge,Mass.), 99, 1999
|
|
1GB1
 | |
7S21
 | | M. xanthus encapsulin shell protein EncA with T=1 symmetry | | Descriptor: | EncA | | Authors: | Eren, E. | | Deposit date: | 2021-09-02 | | Release date: | 2022-02-02 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
|
|
7S20
 | | M. xanthus encapsulin shell protein EncA with T=3 symmetry | | Descriptor: | EncA | | Authors: | Eren, E. | | Deposit date: | 2021-09-02 | | Release date: | 2022-02-02 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
|
|
7S2T
 | | M. xanthus encapsulin EncA bound to EncB targeting peptide | | Descriptor: | EncA, EncB targeting peptide | | Authors: | Eren, E. | | Deposit date: | 2021-09-03 | | Release date: | 2022-02-02 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
|
|
7S4Q
 | | M. xanthus encapsulin EncA bound to EncC targeting peptide | | Descriptor: | EncA, EncC targeting peptide | | Authors: | Eren, E. | | Deposit date: | 2021-09-09 | | Release date: | 2022-02-02 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
|
|
