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CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称:	CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ...
著者	Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986

3TMN

THE BINDING OF L-VALYL-L-TRYPTOPHAN TO CRYSTALLINE THERMOLYSIN ILLUSTRATES THE MODE OF INTERACTION OF A PRODUCT OF PEPTIDE HYDROLYSIS
分子名称:	CALCIUM ION, THERMOLYSIN, TRYPTOPHAN, ...
著者	Holden, H.M, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis. J.Biol.Chem., 263, 1988

7TLN

STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR
分子名称:	2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER, CALCIUM ION, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A, Tronrud, D.E.
登録日	1983-01-27
公開日	1983-03-09
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor. Biochemistry, 22, 1983

4TLN

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称:	CALCIUM ION, L-LEUCYL-HYDROXYLAMINE, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A.
登録日	1982-02-08
公開日	1982-05-26
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20, 1981

8TLN

STRUCTURAL COMPARISON SUGGESTS THAT THERMOLYSIN AND RELATED NEUTRAL PROTEASES UNDERGO HINGE-BENDING MOTION DURING CATALYSIS
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Tronrud, D, Matthews, B.W.
登録日	1993-09-01
公開日	1994-04-30
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis. Biochemistry, 31, 1992

3LZM

STRUCTURAL STUDIES OF MUTANTS OF T4 LYSOZYME THAT ALTER HYDROPHOBIC STABILIZATION
分子名称:	T4 LYSOZYME
著者	Wilson, K, Faber, R, Dao-Pin, S, Matthews, B.W.
登録日	1989-05-01
公開日	1990-01-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural studies of mutants of T4 lysozyme that alter hydrophobic stabilization. J.Biol.Chem., 264, 1989

5LZM

COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Bell, J.A, Wilson, K, Zhang, X.-J, Faber, H.R, Nicholson, H, Matthews, B.W.
登録日	1991-01-25
公開日	1992-07-15
最終更新日	2021-06-30
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths. Proteins, 10, 1991

5TLN

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称:	CALCIUM ION, HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A.
登録日	1982-02-08
公開日	1982-05-26
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20, 1981

4LZM

COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Bell, J.A, Wilson, K, Zhang, X.-J, Faber, H.R, Nicholson, H, Matthews, B.W.
登録日	1991-01-25
公開日	1992-07-15
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths. Proteins, 10, 1991

7LZM

COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS
分子名称:	CHLORIDE ION, T4 LYSOZYME
著者	Bell, J.A, Wilson, K, Zhang, X.-J, Faber, H.R, Nicholson, H, Matthews, B.W.
登録日	1991-01-25
公開日	1992-07-15
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths. Proteins, 10, 1991

6LZM

COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Bell, J.A, Wilson, K, Zhang, X.-J, Faber, H.R, Nicholson, H, Matthews, B.W.
登録日	1991-01-25
公開日	1992-07-15
最終更新日	2021-06-30
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths. Proteins, 10, 1991

1TLP

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称:	CALCIUM ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, THERMOLYSIN, ...
著者	Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986

3RP2

THE STRUCTURE OF RAT MAST CELL PROTEASE II AT 1.9-ANGSTROMS RESOLUTION
分子名称:	RAT MAST CELL PROTEASE II
著者	Reynolds, R, Remington, S, Weaver, L, Fischer, R, Anderson, W, Ammon, H, Matthews, B.
登録日	1984-09-10
公開日	1984-10-29
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	The structure of rat mast cell protease II at 1.9-A resolution. Biochemistry, 27, 1988

1TMN

Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases
分子名称:	CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ...
著者	Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases Biochemistry, 23, 1984

4FGF

REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
分子名称:	BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SULFATE ION
著者	Eriksson, A.E, Matthews, B.W.
登録日	1993-02-26
公開日	1993-07-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993

1QUH

L99G/E108V MUTANT OF T4 LYSOZYME
分子名称:	CHLORIDE ION, HEXANE-1,6-DIOL, PROTEIN (LYSOZYME)
著者	Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W.
登録日	1999-07-01
公開日	1999-07-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability. J.Mol.Biol., 292, 1999

1QUO

L99A/E108V MUTANT OF T4 LYSOZYME
分子名称:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
著者	Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W.
登録日	1999-07-01
公開日	1999-07-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability. J.Mol.Biol., 292, 1999

1QUD

L99G MUTANT OF T4 LYSOZYME
分子名称:	CHLORIDE ION, HEXANE-1,6-DIOL, PROTEIN (LYSOZYME)
著者	Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W.
登録日	1999-07-01
公開日	1999-07-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability. J.Mol.Biol., 292, 1999

1QUG

E108V MUTANT OF T4 LYSOZYME
分子名称:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
著者	Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W.
登録日	1999-07-01
公開日	1999-07-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability. J.Mol.Biol., 292, 1999

5CRO

REFINED STRUCTURE OF CRO REPRESSOR PROTEIN FROM BACTERIOPHAGE LAMBDA
分子名称:	CRO REPRESSOR PROTEIN, PHOSPHATE ION
著者	Ohlendorf, D.H, Tronrud, D.E, Matthews, B.W.
登録日	1998-04-17
公開日	1998-06-17
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Refined structure of Cro repressor protein from bacteriophage lambda suggests both flexibility and plasticity. J.Mol.Biol., 280, 1998

1FGA

REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
分子名称:	BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SELENATE ION
著者	Eriksson, A.E, Matthews, B.W.
登録日	1993-02-26
公開日	1993-07-15
最終更新日	2020-07-22
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993

1L63

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L55

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L61

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L62

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

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