1MMU
| Crystal structure of galactose mutarotase from Lactococcus lactis complexed with D-glucose | Descriptor: | Aldose 1-epimerase, SODIUM ION, beta-D-glucopyranose | Authors: | Thoden, J.B, Kim, J, Raushel, F.M, Holden, H.M. | Deposit date: | 2002-09-04 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis. J.Biol.Chem., 277, 2002
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1MMX
| Crystal structure of galactose mutarotase from Lactococcus lactis complexed with D-fucose | Descriptor: | Aldose 1-epimerase, SODIUM ION, alpha-L-fucopyranose | Authors: | Thoden, J.B, Kim, J, Raushel, F.M, Holden, H.M. | Deposit date: | 2002-09-04 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis. J.Biol.Chem., 277, 2002
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1MMZ
| Crystal structure of galactose mutarotase from Lactococcus lactis complexed with L-arabinose | Descriptor: | Aldose 1-epimerase, SODIUM ION, beta-L-arabinopyranose | Authors: | Thoden, J.B, Kim, J, Raushel, R.M, Holden, H.M. | Deposit date: | 2002-09-04 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis. J.Biol.Chem., 277, 2002
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8EWU
| X-ray structure of the GDP-6-deoxy-4-keto-D-lyxo-heptose-4-reductase from Campylobacter jejuni HS:15 | Descriptor: | 1,2-ETHANEDIOL, GDP-L-fucose synthase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Thoden, J.B, Xiang, D.F, Ghosh, M.K, Riegert, A.S, Raushel, F.M, Holden, H.M. | Deposit date: | 2022-10-24 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Bifunctional Epimerase/Reductase Enzymes Facilitate the Modulation of 6-Deoxy-Heptoses Found in the Capsular Polysaccharides of Campylobacter jejuni. Biochemistry, 62, 2023
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1BSL
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5J63
| Crystal Structure of the N-terminal N-formyltransferase Domain (residues 1-306) of Escherichia coli Arna in Complex with UDP-Ara4N and Folinic Acid | Descriptor: | (2R,3R,4S,5S)-5-amino-3,4-dihydroxytetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, (4aS,6S)-2-amino-6-{(E)-[(4-methylphenyl)imino]methyl}-4-oxo-4,6,7,8-tetrahydropteridine-5(4aH)-carbaldehyde, Bifunctional polymyxin resistance protein ArnA | Authors: | Thoden, J.B, Genthe, N.A, Holden, H.M. | Deposit date: | 2016-04-04 | Release date: | 2016-05-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Escherichia coli ArnA N-formyltransferase domain in complex with N(5) -formyltetrahydrofolate and UDP-Ara4N. Protein Sci., 25, 2016
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3ETJ
| Crystal structure E. coli Purk in complex with Mg, ADP, and Pi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROGENPHOSPHATE ION, ... | Authors: | Holden, H.M, Thoden, J.B. | Deposit date: | 2008-10-08 | Release date: | 2008-10-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli. Biochemistry, 47, 2008
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3ETH
| Crystal structure of E. coli Purk in complex with MgATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole carboxylase ATPase subunit | Authors: | Holden, H.M, Thoden, J.B. | Deposit date: | 2008-10-08 | Release date: | 2008-10-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli. Biochemistry, 47, 2008
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6VLO
| X-ray Structure of the R141 Sugar 4,6-dehydratase from Acanthamoeba polyphaga Minivirus | Descriptor: | NICKEL (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative dTDP-D-glucose 4,6-dehydratase, ... | Authors: | Thoden, J.B, Ferek, J.D, Holden, H.M. | Deposit date: | 2020-01-24 | Release date: | 2020-03-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Biochemical analysis of a sugar 4,6-dehydratase from Acanthamoeba polyphaga Mimivirus. Protein Sci., 29, 2020
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4KCF
| X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose | Descriptor: | FAD-dependent oxidoreductase, FLAVIN MONONUCLEOTIDE, [(2R,4S,6R)-4-azanyl-4,6-dimethyl-5,5-bis(oxidanyl)oxan-2-yl] [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | Authors: | Holden, H.M, Thoden, J.B, Branch, M.C, Zimmer, A.L, Bruender, N.A. | Deposit date: | 2013-04-24 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Active site architecture of a sugar N-oxygenase. Biochemistry, 52, 2013
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4XD1
| X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens, W305A mutant, in the presence of TDP-Qui3N and N5-THF | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... | Authors: | Thoden, J.B, Woodford, C.R, Holden, H.M. | Deposit date: | 2014-12-18 | Release date: | 2015-01-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens. Biochemistry, 54, 2015
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4XD0
| X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens | Descriptor: | (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... | Authors: | Thoden, J.B, Woodford, C.R, Holden, H.M. | Deposit date: | 2014-12-18 | Release date: | 2015-01-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens. Biochemistry, 54, 2015
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4XCZ
| X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens in complex with TDP-Qui3n and N5-THF | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... | Authors: | Thoden, J.B, Woodford, C.R, Holden, H.M. | Deposit date: | 2014-12-18 | Release date: | 2015-01-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens. Biochemistry, 54, 2015
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8DAK
| Crystal structure of the GDP-D-glycero-4-keto-d-lyxo-heptose-3-epimerase from Campylobacter jejuni, serotype HS:3 | Descriptor: | CHLORIDE ION, GDP-D-glycero-4-keto-d-lyxo-heptose-3-epimerase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Thoden, J.B, Ghosh, M.K, Xiang, D.F, Raushel, F.M, Holden, H.M. | Deposit date: | 2022-06-13 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni . Biochemistry, 61, 2022
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8DB5
| Crystal structure of the GDP-D-glycero-4-keto-d-lyxo-heptose-3,5-epimerase from Campylobacter jejuni, serotype HS:15 | Descriptor: | CHLORIDE ION, GDP-D-glycero-4-keto-d-lyxo-heptose-3,5-epimerase, GUANOSINE-5'-DIPHOSPHATE | Authors: | Thoden, J.B, Ghosh, M.K, Xiang, D.F, Raushel, F.M, Holden, H.M. | Deposit date: | 2022-06-14 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni . Biochemistry, 61, 2022
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8DCL
| Crystal structure of the GDP-D-glycero-4-keto-D-lyxo-heptose-3-epimerase from campylobacter jejuni, serotype HS:23/36 | Descriptor: | 1,2-ETHANEDIOL, GDP-D-glycero-4-keto-D-lyxo-heptose-3-epimerase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Thoden, J.B, Ghosh, M.K, Xiang, D.F, Raushel, F.M, Holden, H.M. | Deposit date: | 2022-06-16 | Release date: | 2022-06-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni . Biochemistry, 61, 2022
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8DCO
| Crystal structure of the GDP-D-glycero-4-keto-D-lyxo-heptose-3,5-epimerase from Campylobacter jejuni, serotype HS:42 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GDP-D-glycero-4-keto-D-lyxo-heptose-3,5-epimerase, ... | Authors: | Thoden, J.B, Xiang, D.F, Ghosh, M.K, Raushel, F.M, Holden, H.M. | Deposit date: | 2022-06-17 | Release date: | 2022-06-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni . Biochemistry, 61, 2022
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7US5
| X-ray crystal structure of GDP-D-glycero-D-manno-heptose 4,6-Dehydratase from Campylobacter jejuni | Descriptor: | 1,2-ETHANEDIOL, GDP-D-GLYCERO-D-MANNO-HEPTOSE 4,6-DEHYDRATASE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Thoden, J.B, Xiang, D.F, Raushel, F.M, Holden, H.M. | Deposit date: | 2022-04-23 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Reaction Mechanism and Three-Dimensional Structure of GDP-d-glycero-alpha-d-manno-heptose 4,6-Dehydratase from Campylobacter jejuni. Biochemistry, 61, 2022
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5BSZ
| X-ray structure of the sugar N-methyltransferase KedS8 from Streptoalloteichus sp ATCC 53650 | Descriptor: | 1,2-ETHANEDIOL, N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Thoden, J.B, Delvaux, N.A, Holden, H.M. | Deposit date: | 2015-06-02 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular architecture of KedS8, a sugar N-methyltransferase from Streptoalloteichus sp. ATCC 53650. Protein Sci., 24, 2015
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8V4H
| X-ray structure of the NADP-dependent reductase from Campylobacter jejuni responsible for the synthesis of CDP-glucitol in the presence of CDP-glucitol | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Putative nucleotide sugar dehydratase, ... | Authors: | Thoden, J.B, Schumann, M.E, Holden, H.M, Raushel, F.M. | Deposit date: | 2023-11-29 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biosynthesis of Cytidine Diphosphate-6-d-Glucitol for the Capsular Polysaccharides of Campylobacter jejuni. Biochemistry, 63, 2024
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8SXY
| X-ray crystal structure of UDP- 2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27 in complex with its product UDP-2,3-diacetamido-2,3-dideoxy-d-mannuronic acid at pH 5 | Descriptor: | (2~{S},3~{S},4~{R},5~{S},6~{R})-4,5-diacetamido-6-[[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxane-2-carboxylic acid, CHLORIDE ION, UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase | Authors: | McKnight, J.O, Thoden, J.B, Holden, H.M. | Deposit date: | 2023-05-24 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
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8SYH
| X-ray crystal structure of UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27, D98N variant in the presence of UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid and UDP at pH 8 | Descriptor: | (2~{S},3~{S},4~{R},5~{R},6~{R})-4,5-diacetamido-6-[[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxane-2-carboxylic acid, CHLORIDE ION, UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase, ... | Authors: | Jast, J.D.T, Thoden, J.B, Holden, H.M. | Deposit date: | 2023-05-25 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
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8SY0
| X-ray crystal structure of UDP- 2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27 in complex with its product UDP-2,3-diacetamido-2,3-dideoxy-d-mannuronic acid at pH 9 | Descriptor: | (2~{S},3~{S},4~{R},5~{S},6~{R})-4,5-diacetamido-6-[[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxane-2-carboxylic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | McKnight, J.O, Thoden, J.B, Holden, H.M. | Deposit date: | 2023-05-24 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
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8SXV
| X-ray crystal structure of UDP- 2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27, apo form, pH 9 | Descriptor: | CHLORIDE ION, UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase | Authors: | McKnight, J.O, Thoden, J.B, Holden, H.M. | Deposit date: | 2023-05-24 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
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8SYD
| X-ray crystal structure of UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27, D98N variant in the presence of UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid and UDP-N-acetylglucosamine at pH 6 | Descriptor: | (2~{S},3~{S},4~{R},5~{R},6~{R})-4,5-diacetamido-6-[[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxane-2-carboxylic acid, CHLORIDE ION, UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase, ... | Authors: | Kroft, C.W, Thoden, J.B, Holden, H.M. | Deposit date: | 2023-05-25 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
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