8S2X
 
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8S2V
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8S2U
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8S2W
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3BB1
 | | Crystal structure of Toc34 from Pisum sativum in complex with Mg2+ and GMPPNP | | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Koenig, P, Sinning, I, Schleiff, E, Tews, I. | | Deposit date: | 2007-11-09 | | Release date: | 2008-04-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures.
Structure, 16, 2008
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3BB3
 | | Crystal structure of Toc33 from Arabidopsis thaliana in complex with GDP and Mg2+ | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, T7I23.11 protein | | Authors: | Koenig, P, Sinning, I, Schleiff, E, Tews, I. | | Deposit date: | 2007-11-09 | | Release date: | 2008-04-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures.
Structure, 16, 2008
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3BB4
 | | Crystal structure of Toc33 from Arabidopsis thaliana in complex with Mg2+ and GMPPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, T7I23.11 protein | | Authors: | Koenig, P, Sinning, I, Schleiff, E, Tews, I. | | Deposit date: | 2007-11-09 | | Release date: | 2008-04-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures.
Structure, 16, 2008
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4ADS
 | | Crystal structure of plasmodial PLP synthase complex | | Descriptor: | PDX2 PROTEIN, PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, ... | | Authors: | Guedez, G, Sinning, I, Tews, I. | | Deposit date: | 2012-01-03 | | Release date: | 2012-01-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.61 Å) | | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme.
Structure, 20, 2012
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4ADT
 | | Crystal structure of plasmodial PLP synthase | | Descriptor: | PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE | | Authors: | Guedez, G, Sinning, I, Tews, I. | | Deposit date: | 2012-01-03 | | Release date: | 2012-01-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme.
Structure, 20, 2012
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4ADU
 | | Crystal structure of plasmodial PLP synthase with bound R5P intermediate | | Descriptor: | 1,2-ETHANEDIOL, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE, ... | | Authors: | Guedez, G, Sinning, I, Tews, I. | | Deposit date: | 2012-01-03 | | Release date: | 2012-01-25 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme.
Structure, 20, 2012
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6TKB
 | | ChiLob 7/4 H2 HC-C224S F(ab')2 | | Descriptor: | Chilob 7/4 H2 heavy chain C224S, Chilob 7/4 H2 kappa chain | | Authors: | Orr, C.M, Fisher, H, Tews, I. | | Deposit date: | 2019-11-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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6TKE
 | | ChiLob 7/4 H2 HC-C224S Kappa LC-C214S F(ab')2 | | Descriptor: | ChiLob 7/4 H2 heavy chain C224S, ChiLob 7/4 H2 kappa chain C214S | | Authors: | Orr, C.M, Fisher, H, Tews, I. | | Deposit date: | 2019-11-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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6TKF
 | | ChiLob 7/4 H2 HC-C225S KappaLC-C214S F(ab')2 | | Descriptor: | ChiLob 7/4 H2 Heavy chain C225S, ChiLob 7/4 H2 Kappa light chain C214S | | Authors: | Orr, C.M, Fisher, H, Tews, I. | | Deposit date: | 2019-11-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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6TKD
 | | ChiLob 7/4 H2 HC-C228S F(ab')2 | | Descriptor: | Chilob 7/4 H2 heavy chain C228S, Chilob 7/4 H2 kappa chain | | Authors: | Orr, C.M, Fisher, H, Tews, I. | | Deposit date: | 2019-11-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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6TKC
 | | ChiLob 7/4 H2 HC-C225S F(ab')2 | | Descriptor: | Chilob 7/4 H2 heavy chain C225S, Chilob 7/4 H2 kappa chain | | Authors: | Orr, C.M, Fisher, H, Tews, I. | | Deposit date: | 2019-11-28 | | Release date: | 2021-06-09 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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8C4Y
 | | SFX structure of FutA bound to Fe(III) | | Descriptor: | FE (III) ION, Putative iron ABC transporter, substrate binding protein | | Authors: | Bolton, R, Tews, I. | | Deposit date: | 2023-01-05 | | Release date: | 2023-08-30 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6FAX
 | | Complex of Human CD40 Ectodomain with Lob 7.4 Fab | | Descriptor: | Lob 7.4 heavy chain, Lob 7.4 light chain, Tumor necrosis factor receptor superfamily member 5 | | Authors: | Orr, C.M, Tews, I, Pearson, A.R. | | Deposit date: | 2017-12-18 | | Release date: | 2018-02-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies.
Cancer Cell, 33, 2018
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2EV4
 | | Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, with a salt precipitant | | Descriptor: | CHLORIDE ION, Hypothetical protein Rv1264/MT1302, OLEIC ACID | | Authors: | Findeisen, F, Tews, I, Sinning, I. | | Deposit date: | 2005-10-30 | | Release date: | 2006-11-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid
J.Mol.Biol., 369, 2007
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2EV2
 | | Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 8.5 | | Descriptor: | Hypothetical protein Rv1264/MT1302, OLEIC ACID | | Authors: | Findeisen, F, Tews, I, Sinning, I. | | Deposit date: | 2005-10-30 | | Release date: | 2006-11-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid
J.Mol.Biol., 369, 2007
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6G7P
 | | Trichodesmium Tery_3377 (IdiA) (FutA) with iron and water ligands. | | Descriptor: | CHLORIDE ION, Extracellular solute-binding protein, family 1, ... | | Authors: | Machelett, M.M, Tews, I. | | Deposit date: | 2018-04-06 | | Release date: | 2018-09-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and functional characterization of IdiA/FutA (Tery_3377), an iron-binding protein from the ocean diazotrophTrichodesmium erythraeum.
J. Biol. Chem., 293, 2018
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2EV1
 | | Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 6.0 | | Descriptor: | Hypothetical protein Rv1264/MT1302, OLEIC ACID, PENTAETHYLENE GLYCOL | | Authors: | Findeisen, F, Tews, I, Sinning, I. | | Deposit date: | 2005-10-30 | | Release date: | 2006-11-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid
J.Mol.Biol., 369, 2007
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2EV3
 | | Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 5.3 | | Descriptor: | Hypothetical protein Rv1264/MT1302, OLEIC ACID | | Authors: | Findeisen, F, Tews, I, Sinning, I. | | Deposit date: | 2005-10-30 | | Release date: | 2006-11-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid
J.Mol.Biol., 369, 2007
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2ABW
 | | Glutaminase subunit of the plasmodial PLP synthase (Vitamin B6 biosynthesis) | | Descriptor: | Pdx2 protein, TETRAETHYLENE GLYCOL | | Authors: | Gengenbacher, M, Fitzpatrick, T.B, Raschle, T, Flicker, K, Sinning, I, Mueller, S, Macheroux, P, Tews, I, Kappes, B. | | Deposit date: | 2005-07-17 | | Release date: | 2006-01-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Vitamin B6 Biosynthesis by the Malaria Parasite Plasmodium falciparum: Biochemical and structural insights
J.Biol.Chem., 281, 2006
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2NV2
 | | Structure of the PLP synthase complex Pdx1/2 (YaaD/E) from Bacillus subtilis | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLUTAMINE, ... | | Authors: | Strohmeier, M, Tews, I, Sinning, I. | | Deposit date: | 2006-11-10 | | Release date: | 2006-12-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Structure of a bacterial pyridoxal 5'-phosphate synthase complex
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2NV0
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