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5NPA
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BU of 5npa by Molmil
Solution structure of Drosophila melanogaster Loquacious dsRBD2
Descriptor: Loquacious
Authors:Tants, J.-N, Fesser, S, Kern, T, Stehle, R, Geerlof, A, Wunderlich, C, Boettcher, R, Kunzelmann, S, Lange, O, Kreutz, C, Foerstemann, K, Sattler, M.
Deposit date:2017-04-16
Release date:2017-10-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
Nucleic Acids Res., 45, 2017
5NPG
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BU of 5npg by Molmil
Solution structure of Drosophila melanogaster Loquacious dsRBD1
Descriptor: Loquacious, isoform F
Authors:Tants, J.-N, Fesser, S, Kern, T, Stehle, R, Geerlof, A, Wunderlich, C, Hartlmuller, C, Boettcher, R, Kunzelmann, S, Lange, O, Kreutz, C, Foerstemann, K, Sattler, M.
Deposit date:2017-04-16
Release date:2017-10-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
Nucleic Acids Res., 45, 2017
5JS8
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BU of 5js8 by Molmil
Structural Model of a Protein alpha subunit in complex with GDP obtained with SAXS and NMR residual couplings
Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1
Authors:Goricanec, D, Stehle, R, Grigoriu, S, Wagner, G, Hagn, F.
Deposit date:2016-05-07
Release date:2016-06-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JS7
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BU of 5js7 by Molmil
Structural model of a apo G-protein alpha subunit determined with NMR residual dipolar couplings and SAXS
Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1
Authors:Goricanec, D, Stehle, R, Grigoriu, S, Wagner, G, Hagn, F.
Deposit date:2016-05-07
Release date:2016-06-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JU7
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BU of 5ju7 by Molmil
DNA BINDING DOMAIN OF E.COLI CADC
Descriptor: Transcriptional activator CadC, ZINC ION
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2016-05-10
Release date:2017-04-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
Sci Rep, 7, 2017
5M0H
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BU of 5m0h by Molmil
Crystal structure of the central flexible region of ASH1 mRNA E3-localization element
Descriptor: ASH1 E3 (42 nt-TL/TLR), SULFATE ION
Authors:Edelmann, F.T, Janowski, R, Niessing, D.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
Nat. Struct. Mol. Biol., 24, 2017
5M0J
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BU of 5m0j by Molmil
Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element
Descriptor: ASH1 E3 (28 nt-loop), MAGNESIUM ION, SWI5-dependent HO expression protein 2,SWI5-dependent HO expression protein 3
Authors:Edelmann, F.T, Janowski, R, Niessing, D.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
Nat. Struct. Mol. Biol., 24, 2017
5M0I
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BU of 5m0i by Molmil
Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ASH1-E3 element, ...
Authors:Edelmann, F.T, Janowski, R, Niessing, D.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
Nat. Struct. Mol. Biol., 24, 2017
6TR0
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BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Kang, H.-S, Sattler, M.
Deposit date:2019-12-17
Release date:2020-05-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
4UJ5
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BU of 4uj5 by Molmil
Crystal structure of human Rab11-Rabin8-FIP3
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ...
Authors:Vetter, M, Lorentzen, E.
Deposit date:2015-04-08
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11.
Nat.Struct.Mol.Biol., 22, 2015
4UJ3
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BU of 4uj3 by Molmil
Crystal structure of human Rab11-Rabin8-FIP3
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ...
Authors:Vetter, M, Lorentzen, E.
Deposit date:2015-04-08
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11.
Nat.Struct.Mol.Biol., 22, 2015
4UJ4
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BU of 4uj4 by Molmil
Crystal structure of human Rab11-Rabin8-FIP3
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab-3A-interacting protein, ...
Authors:Vetter, M, Lorentzen, E.
Deposit date:2015-04-08
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.
Nat. Struct. Mol. Biol., 22, 2015
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
Authors:Kachariya, N, Sattler, M, Keil, P, Strasser, K.
Deposit date:2022-10-04
Release date:2022-11-09
Last modified:2023-02-08
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
7PCV
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BU of 7pcv by Molmil
Crystal structure of RBM5 RRM1-zinc finger
Descriptor: RNA-binding protein 5, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-04
Release date:2022-08-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
7PDV
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BU of 7pdv by Molmil
Crystal structure of RBM5 RRM1-zinc finger in complex with RNA
Descriptor: RNA (5'-R(P*UP*GP*GP*CP*UP*CP*UP*UP*CP*U)-3'), RNA binding motif protein 5 isoform 1, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-08
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
5ELR
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BU of 5elr by Molmil
Structure of the KH-QUA2 domain of T-STAR in complex with AAUAAU RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-05
Release date:2016-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5EL3
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BU of 5el3 by Molmil
Structure of the KH domain of T-STAR
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-04
Release date:2016-01-13
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5ELS
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BU of 5els by Molmil
Structure of the KH domain of T-STAR in complex with AAAUAA RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-05
Release date:2016-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.873 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5ELT
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BU of 5elt by Molmil
Structure of the QUA1-KH domain of T-STAR in complex with UAAU RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-05
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5EMO
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BU of 5emo by Molmil
Structure of the star domain of T-STAR in complex with AUUAAA RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-06
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5O3J
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BU of 5o3j by Molmil
Crystal structure of TIA-1 RRM2 in complex with RNA
Descriptor: Nucleolysin TIA-1 isoform p40, RNA (5'-R(P*UP*UP*C)-3')
Authors:Sonntag, M, Jagtap, P.K.A, Hennig, J, Sattler, M.
Deposit date:2017-05-24
Release date:2017-07-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
Angew. Chem. Int. Ed. Engl., 56, 2017
5O2V
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BU of 5o2v by Molmil
NMR structure of TIA-1 RRM1 domain
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Jagtap, P.K.A.
Deposit date:2017-05-22
Release date:2017-06-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
Angew. Chem. Int. Ed. Engl., 56, 2017
4QI2
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BU of 4qi2 by Molmil
X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA
Descriptor: RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'), Roquin-1
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2014-05-30
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
4QI0
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BU of 4qi0 by Molmil
X-ray structure of the ROQ domain from murine Roquin-1
Descriptor: 1,2-ETHANEDIOL, Roquin-1
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2014-05-30
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
6GD2
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BU of 6gd2 by Molmil
Structure of HuR RRM3 in complex with RNA
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3')
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019

 

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