6VBU
 
 | | Structure of the bovine BBSome complex | | 分子名称: | BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ... | | 著者 | Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A. | | 登録日 | 2019-12-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Elife, 9, 2020
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6VBV
 | | Structure of the bovine BBSome:ARL6:GTP complex | | 分子名称: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | | 著者 | Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A. | | 登録日 | 2019-12-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Elife, 9, 2020
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5X6N
 | | Structure of P. Knowlesi DBL Domain Capable of binding Human Duffy Antigen | | 分子名称: | Duffy binding protein, SULFATE ION, octyl beta-D-glucopyranoside | | 著者 | Singh, S.K, Hora, R, Belrhali, H, Chitnis, C, Sharma, A. | | 登録日 | 2017-02-22 | | 公開日 | 2017-03-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain
Nature, 439, 2006
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3F4I
 | | Crystal Structure of LeuT bound to L-selenomethionine and sodium | | 分子名称: | SELENOMETHIONINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-31 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3F4J
 | | Crystal structure of LeuT bound to glycine and sodium | | 分子名称: | GLYCINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-31 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3F48
 | | Crystal structure of LeuT bound to L-alanine and sodium | | 分子名称: | ALANINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-31 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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1HQS
 | | CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE FROM BACILLUS SUBTILIS | | 分子名称: | CITRIC ACID, ISOCITRATE DEHYDROGENASE, R-1,2-PROPANEDIOL, ... | | 著者 | Singh, S.K, Matsuno, K, LaPorte, D.C, Banaszak, L.J. | | 登録日 | 2000-12-19 | | 公開日 | 2001-07-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of Bacillus subtilis isocitrate dehydrogenase at 1.55 A. Insights into the nature of substrate specificity exhibited by Escherichia coli isocitrate dehydrogenase kinase/phosphatase.
J.Biol.Chem., 276, 2001
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1LW7
 | | NADR PROTEIN FROM HAEMOPHILUS INFLUENZAE | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, TRANSCRIPTIONAL REGULATOR NADR | | 著者 | Singh, S.K, Kurnasov, O.V, Chen, B, Robinson, H, Grishin, N.V, Osterman, A.L, Zhang, H. | | 登録日 | 2002-05-30 | | 公開日 | 2002-08-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of Haemophilus influenzae NadR protein. A bifunctional enzyme endowed with NMN adenyltransferase and ribosylnicotinimide kinase activities.
J.Biol.Chem., 277, 2002
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1RKU
 | | Crystal Structure of ThrH gene product of Pseudomonas Aeruginosa | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, homoserine kinase | | 著者 | Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H. | | 登録日 | 2003-11-23 | | 公開日 | 2004-03-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity.
J.Biol.Chem., 279, 2004
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1RKV
 | | Structure of Phosphate complex of ThrH from Pseudomonas aeruginosa | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H. | | 登録日 | 2003-11-23 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity.
J.Biol.Chem., 279, 2004
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2Q72
 | | Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine | | 分子名称: | 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, LEUCINE, SODIUM ION, ... | | 著者 | Singh, S.K, Yamashita, A, Gouaux, E. | | 登録日 | 2007-06-05 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.
Nature, 448, 2007
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2QB4
 | | Crystal Structure Analysis of LeuT complexed with L-leucine, sodium and desipramine | | 分子名称: | 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, LEUCINE, SODIUM ION, ... | | 著者 | Singh, S.K, Yamashita, A, Gouaux, E. | | 登録日 | 2007-06-15 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.
Nature, 448, 2007
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2QEI
 | | Crystal structure analysis of LeuT complexed with L-alanine, sodium, and clomipramine | | 分子名称: | 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, ALANINE, SODIUM ION, ... | | 著者 | Singh, S.K, Yamashita, A, Gouaux, E. | | 登録日 | 2007-06-25 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.
Nature, 448, 2007
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3F3A
 | | Crystal Structure of LeuT bound to L-Tryptophan and Sodium | | 分子名称: | SODIUM ION, TETRADECANE, TRYPTOPHAN, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-30 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3F3D
 | | Crystal structure of LeuT bound to L-Methionine and sodium | | 分子名称: | METHIONINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-30 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3F3E
 | | Crystal structure of LeuT bound to L-leucine (30 mM) and sodium | | 分子名称: | LEUCINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-30 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3F3C
 | | Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium | | 分子名称: | 4-FLUORO-L-PHENYLALANINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-30 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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2Q6H
 | | Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and clomipramine | | 分子名称: | 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, LEUCINE, SODIUM ION, ... | | 著者 | Singh, S.K, Yamashita, A, Gouaux, E. | | 登録日 | 2007-06-05 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.
Nature, 448, 2007
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3NSY
 | | The multi-copper oxidase CueO with six Met to Ser mutations (M358S,M361S,M362S,M364S,M366S,M368S) | | 分子名称: | Blue copper oxidase cueO, COPPER (II) ION, CU-O-CU LINKAGE | | 著者 | Roberts, S.A, Montfort, W.R, Singh, S.K. | | 登録日 | 2010-07-02 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
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3NSF
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3NSC
 | | C500S MUTANT OF CueO BOUND TO Cu(II) | | 分子名称: | ACETATE ION, Blue copper oxidase cueO, COPPER (II) ION, ... | | 著者 | Roberts, S.A, Montfort, W.R, Singh, S.K. | | 登録日 | 2010-07-01 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
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3NT0
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3NSD
 | | Silver bound to the multicopper oxidase CueO (untagged) | | 分子名称: | Blue copper oxidase cueO, COPPER (II) ION, OXYGEN ATOM, ... | | 著者 | Montfort, W.R, Roberts, S.A, Singh, S.K. | | 登録日 | 2010-07-01 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
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3OD3
 | | CueO at 1.1 A resolution including residues in previously disordered region | | 分子名称: | 1,2-ETHANEDIOL, Blue copper oxidase cueO, COPPER (II) ION, ... | | 著者 | Montfort, W.R, Roberts, S.A, Singh, S.K. | | 登録日 | 2010-08-10 | | 公開日 | 2011-09-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
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3QQX
 | | Reduced Native Intermediate of the Multicopper Oxidase CueO | | 分子名称: | Blue copper oxidase CueO, COPPER (I) ION, COPPER (II) ION, ... | | 著者 | Montfort, W.R, Roberts, S.A, Singh, S.K. | | 登録日 | 2011-02-16 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | CueO E506D Mutant: Crystal Structure of Reduced Native Intermediate, Kinetics, and Impairment of Product Release
To be Published
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