1OI2
 
 | | X-ray structure of the dihydroxyacetone kinase from Escherichia coli | | 分子名称: | GLYCEROL, HYPOTHETICAL PROTEIN YCGT, SULFATE ION | | 著者 | Siebold, C, Garcia-Alles, L.-F, Erni, B, Baumann, U. | | 登録日 | 2003-06-04 | | 公開日 | 2003-06-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Mechanism of Covalent Substrate Binding in the X-Ray Structure of Subunit K of the Escherichia Coli Dihydroxyacetone Kinase
Proc.Natl.Acad.Sci.USA, 100, 2003
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1OI3
 | | X-ray structure of the dihydroxyacetone kinase from Escherichia coli | | 分子名称: | HYPOTHETICAL PROTEIN YCGT, SULFATE ION | | 著者 | Siebold, C, Garcia-Alles, L.-F, Erni, B, Baumann, U. | | 登録日 | 2003-06-04 | | 公開日 | 2003-07-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Mechanism of Covalent Substrate Binding in the X-Ray Structure of Subunit K of the Escherichia Coli Dihydroxyacetone Kinase
Proc.Natl.Acad.Sci.USA, 100, 2003
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1UN8
 | | Crystal structure of the dihydroxyacetone kinase of C. freundii (native form) | | 分子名称: | (2R)-3-(PHOSPHONOOXY)-2-(TETRADECANOYLOXY)PROPYL PALMITATE, DIHYDROXYACETONE KINASE | | 著者 | Siebold, C, Arnold, I, Garcia-Alles, L.F, Baumann, U, Erni, B. | | 登録日 | 2003-09-08 | | 公開日 | 2003-10-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the Citrobacter Freundii Dihydroxyacetone Kinase Reveals an Eight-Stranded Alpha-Helical Barrel ATP-Binding Domain
J.Biol.Chem., 278, 2003
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1UN9
 | | Crystal structure of the dihydroxyacetone kinase from C. freundii in complex with AMP-PNP and Mg2+ | | 分子名称: | DIHYDROXYACETONE, DIHYDROXYACETONE KINASE, MAGNESIUM ION, ... | | 著者 | Siebold, C, Arnold, I, Garcia-Alles, L.F, Baumann, U, Erni, B. | | 登録日 | 2003-09-08 | | 公開日 | 2003-10-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structure of the Citrobacter Freundii Dihydroxyacetone Kinase Reveals an Eight-Stranded Alpha-Helical Barrel ATP-Binding Domain
J.Biol.Chem., 278, 2003
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1UVQ
 | | Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, GLYCINE, ... | | 著者 | Siebold, C, Hansen, B.E, Wyer, J.R, Harlos, K, Esnouf, R.E, Svejgaard, A, Bell, J.I, Strominger, J.L, Jones, E.Y, Fugger, L. | | 登録日 | 2004-01-22 | | 公開日 | 2004-02-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
Proc.Natl.Acad.Sci.USA, 101, 2004
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2BRY
 | | Crystal structure of the native monooxygenase domain of MICAL at 1.45 A resolution | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Siebold, C, Berrow, N, Walter, T.S, Harlos, K, Owens, R.J, Terman, J.R, Stuart, D.I, Kolodkin, A.L, Pasterkamp, R.J, Jones, E.Y. | | 登録日 | 2005-05-13 | | 公開日 | 2005-10-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | High-Resolution Structure of the Catalytic Region of Mical (Molecule Interacting with Casl), a Multidomain Flavoenzyme-Signaling Molecule.
Proc.Natl.Acad.Sci.USA, 102, 2005
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2C4C
 | | Crystal structure of the NADPH-treated monooxygenase domain of MICAL | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9-INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS | | 著者 | Siebold, C, Berrow, N, Walter, T.S, Harlos, K, Owens, R.J, Terman, J.R, Stuart, D.I, Kolodkin, A.L, Pasterkamp, R.J, Jones, E.Y. | | 登録日 | 2005-10-18 | | 公開日 | 2005-10-26 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | High-Resolution Structure of the Catalytic Region of Mical (Molecule Interacting with Casl), a Multidomain Flavoenzyme-Signaling Molecule.
Proc.Natl.Acad.Sci.USA, 102, 2005
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1UOD
 | | Crystal structure of the dihydroxyacetone kinase from E. coli in complex with dihydroxyacetone-phosphate | | 分子名称: | DIHYDROXYACETONE KINASE, GLYCERALDEHYDE-3-PHOSPHATE, SULFATE ION | | 著者 | Siebold, C, Garcia-Alles, L.F, Luthi-Nyffeler, T, Flukiger-Bruhwiler, K, Burgi, H.-B, Baumann, U, Erni, B. | | 登録日 | 2003-09-16 | | 公開日 | 2004-09-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Phosphoenolpyruvate- and ATP-Dependent Dihydroxyacetone Kinases: Covalent Substrate-Binding and Kinetic Mechanism
Biochemistry, 43, 2004
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1UOE
 | | Crystal structure of the dihydroxyacetone kinase from E. coli in complex with glyceraldehyde | | 分子名称: | DIHYDROXYACETONE KINASE, GLYCEROL, SULFATE ION | | 著者 | Siebold, C, Garcia-Alles, L.F, Luthi-Nyffeler, T, Flukiger-Bruhwiler, K, Burgi, H.-B, Baumann, U, Erni, B. | | 登録日 | 2003-09-16 | | 公開日 | 2004-09-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Phosphoenolpyruvate- and ATP-Dependent Dihydroxyacetone Kinases: Covalent Substrate-Binding and Kinetic Mechanism
Biochemistry, 43, 2004
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2UUX
 | | Structure of the tryptase inhibitor TdPI from a tick | | 分子名称: | SULFATE ION, TRYPTASE INHIBITOR | | 著者 | Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I. | | 登録日 | 2007-03-08 | | 公開日 | 2007-04-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
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2UUY
 | | Structure of a tick tryptase inhibitor in complex with bovine trypsin | | 分子名称: | CALCIUM ION, CATIONIC TRYPSIN, CHLORIDE ION, ... | | 著者 | Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I. | | 登録日 | 2007-03-08 | | 公開日 | 2007-04-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
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7ZI0
 | | Structure of human Smoothened in complex with cholesterol and SAG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide, CHOLESTEROL, ... | | 著者 | Byrne, E.F.X, Woolley, R.E, Ansell, B, Sansom, M.S.P, Newstead, S, Siebold, C. | | 登録日 | 2022-04-07 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Sci Adv, 8, 2022
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1W9Z
 | | Structure of Bannavirus VP9 | | 分子名称: | VP9 | | 著者 | Jaafar, F.M, Attoui, H, Bahar, M.W, Siebold, C, Sutton, G, Mertens, P.P.C, Micco, P, Stuart, D.I, Grimes, J.M, Lamballerie, X. | | 登録日 | 2004-10-21 | | 公開日 | 2005-04-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | The Structure and Function of the Outer Coat Protein Vp9 of Banna Virus
Structure, 13, 2005
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4A0P
 | | Crystal structure of LRP6P3E3P4E4 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chen, S, Malinauskas, T, Aricescu, A.R, Siebold, C, Jones, E.Y. | | 登録日 | 2011-09-11 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling.
Dev.Cell, 21, 2011
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5KC8
 | | Crystal structure of the amino-terminal domain (ATD) of iGluR Delta-2 (GluD2) | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Glutamate receptor ionotropic, ... | | 著者 | Elegheert, J, Clay, J.E, Siebold, C, Aricescu, A.R. | | 登録日 | 2016-06-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Structural basis for integration of GluD receptors within synaptic organizer complexes.
Science, 353, 2016
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5KC5
 | | Crystal structure of the Cbln1 C1q domain trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | | 著者 | Elegheert, J, Clay, J.E, Siebold, C, Aricescu, A.R. | | 登録日 | 2016-06-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | | 主引用文献 | Structural basis for integration of GluD receptors within synaptic organizer complexes.
Science, 353, 2016
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5KC9
 | | Crystal structure of the amino-terminal domain (ATD) of iGluR Delta-1 (GluD1) | | 分子名称: | 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Elegheert, J, Clay, J.E, Siebold, C, Aricescu, A.R. | | 登録日 | 2016-06-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for integration of GluD receptors within synaptic organizer complexes.
Science, 353, 2016
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6Z3J
 | | Repulsive Guidance Molecule B (RGMB) in complex with Growth Differentiation Factor 5 (GDF5) (crystal form 1) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Malinauskas, T, Peer, T.V, Bishop, B, Muller, T.D, Siebold, C. | | 登録日 | 2020-05-20 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5L7I
 | | Structure of human Smoothened in complex with Vismodegib | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, SODIUM ION, ... | | 著者 | Byrne, E.X.B, Sircar, R, Miller, P.S, Hedger, G, Luchetti, G, Nachtergaele, S, Tully, M.D, Mydock-McGrane, L, Covey, D.F, Rambo, R.F, Sansom, M.S.P, Newstead, S, Rohatgi, R, Siebold, C. | | 登録日 | 2016-06-03 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
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5L7D
 | | Structure of human Smoothened in complex with cholesterol | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, SODIUM ION, ... | | 著者 | Byrne, E.F.X, Sircar, R, Miller, P.S, Hedger, G, Luchetti, G, Nachtergaele, S, Tully, M.D, Mydock-McGrane, L, Covey, D.F, Rambo, R.P, Sansom, M.S.P, Newstead, S, Rohatgi, R, Siebold, C. | | 登録日 | 2016-06-03 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
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3OKT
 | | Mouse Plexin A2, extracellular domains 1-4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y. | | 登録日 | 2010-08-25 | | 公開日 | 2010-10-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | | 主引用文献 | Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
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3OKW
 | | Mouse Semaphorin 6A, extracellular domains 1-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | | 著者 | Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y. | | 登録日 | 2010-08-25 | | 公開日 | 2010-10-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
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4UI1
 | | Crystal structure of the human RGMC-BMP2 complex | | 分子名称: | 1,2-ETHANEDIOL, BONE MORPHOGENETIC PROTEIN 2, CHLORIDE ION, ... | | 著者 | Healey, E.G, Bishop, B, Elegheert, J, Bell, C.H, Padilla-Parra, S, Siebold, C. | | 登録日 | 2015-03-27 | | 公開日 | 2015-05-06 | | 最終更新日 | 2015-06-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
Nat.Struct.Mol.Biol., 22, 2015
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4UHY
 | | Crystal structure of the human RGMA-BMP2 complex | | 分子名称: | BONE MORPHOGENETIC PROTEIN 2, REPULSIVE GUIDANCE MOLECULE A | | 著者 | Healey, E.G, Bishop, B, Elegheert, J, Bell, C.H, Padilla-Parra, S, Siebold, C. | | 登録日 | 2015-03-27 | | 公開日 | 2015-05-06 | | 最終更新日 | 2015-06-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
Nat.Struct.Mol.Biol., 22, 2015
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4UHZ
 | | Crystal structure of the human RGMB-BMP2 complex, crystal form 1 | | 分子名称: | BONE MORPHOGENETIC PROTEIN 2, RGM DOMAIN FAMILY MEMBER B, SULFATE ION | | 著者 | Healey, E.G, Bishop, B, Elegheert, J, Bell, C.H, Padilla-Parra, S, Siebold, C. | | 登録日 | 2015-03-27 | | 公開日 | 2015-05-06 | | 最終更新日 | 2015-06-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
Nat.Struct.Mol.Biol., 22, 2015
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