3NNL
 
 | | Halogenase domain from CurA module (crystal form III) | | Descriptor: | 2-OXOGLUTARIC ACID, CHLORIDE ION, CurA, ... | | Authors: | Khare, D, Smith, J.L. | | Deposit date: | 2010-06-23 | | Release date: | 2010-07-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.883 Å) | | Cite: | Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
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3NNF
 | | Halogenase domain from CurA module with Fe, chloride, and alpha-ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, CHLORIDE ION, CurA, ... | | Authors: | Khare, D, Smith, J.L. | | Deposit date: | 2010-06-23 | | Release date: | 2010-07-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
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7R7G
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7R7F
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7R7E
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6MFD
 | | GphF GNAT-like decarboxylase in complex with isobutyryl-CoA | | Descriptor: | ACETATE ION, GLYCEROL, GphF, ... | | Authors: | Skiba, M.A, Tran, C.L, Smith, J.L. | | Deposit date: | 2018-09-10 | | Release date: | 2019-09-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.794 Å) | | Cite: | Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
Structure, 28, 2020
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6MFC
 | | GphF GNAT-like decarboxylase | | Descriptor: | GLYCEROL, GphF, PENTAETHYLENE GLYCOL | | Authors: | Skiba, M.A, Tran, C.L, Smith, J.L. | | Deposit date: | 2018-09-10 | | Release date: | 2019-09-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.589 Å) | | Cite: | Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
Structure, 28, 2020
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6O5G
 | | Calmodulin in complex with isomalbrancheamide D | | Descriptor: | (5aS,12aS,13aS)-9-bromo-8-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7 ,6-b]carbazol-14-one, CALCIUM ION, Calmodulin-1, ... | | Authors: | Beyett, T.S, Fraley, A.E, Tesmer, J.J.G. | | Deposit date: | 2019-03-02 | | Release date: | 2019-08-07 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe.
Proc.Natl.Acad.Sci.USA, 116, 2019
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3NNM
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3SSO
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3SSN
 | | MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg, SAH, and Mycinamycin VI | | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Akey, D.L, Smith, J.L. | | Deposit date: | 2011-07-08 | | Release date: | 2011-08-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.392 Å) | | Cite: | A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
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3SSM
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3TO3
 | | Crystal Structure of Petrobactin Biosynthesis Protein AsbB from Bacillus anthracis str. Sterne | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Kim, Y, Eschenfeldt, W, Stols, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-09-03 | | Release date: | 2011-10-05 | | Last modified: | 2012-06-06 | | Method: | X-RAY DIFFRACTION (2.382 Å) | | Cite: | Functional and Structural Analysis of the Siderophore Synthetase AsbB through Reconstitution of the Petrobactin Biosynthetic Pathway from Bacillus anthracis.
J.Biol.Chem., 287, 2012
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5WGY
 | | Crystal Structure of MalA' C112S/C128S, malbrancheamide B complex | | Descriptor: | (5aS,12aS,13aS)-9-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, CADMIUM ION, CHLORIDE ION, ... | | Authors: | Fraley, A.E, Smith, J.L. | | Deposit date: | 2017-07-14 | | Release date: | 2017-08-16 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids.
J. Am. Chem. Soc., 139, 2017
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5WM6
 | | Crystal Structure of CahJ in Complex with Benzoyl Adenylate | | Descriptor: | 5'-O-[(R)-(benzoyloxy)(hydroxy)phosphoryl]adenosine, ACETATE ION, MAGNESIUM ION, ... | | Authors: | Sikkema, A.P, Smith, J.L. | | Deposit date: | 2017-07-28 | | Release date: | 2018-05-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
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5WGW
 | | Crystal Structure of Wild-type MalA', malbrancheamide B complex | | Descriptor: | (5aS,12aS,13aS)-9-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, CADMIUM ION, CHLORIDE ION, ... | | Authors: | Fraley, A.E, Smith, J.L. | | Deposit date: | 2017-07-14 | | Release date: | 2017-08-16 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (2.092 Å) | | Cite: | Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids.
J. Am. Chem. Soc., 139, 2017
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5WM7
 | | Crystal Structure of CahJ in Complex with AMP | | Descriptor: | ACETATE ION, ADENOSINE MONOPHOSPHATE, GLYCEROL, ... | | Authors: | Sikkema, A.P, Smith, J.L. | | Deposit date: | 2017-07-28 | | Release date: | 2018-05-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.777 Å) | | Cite: | A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
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6B3A
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6B3B
 | | AprA Methyltransferase 1 - GNAT in complex with Mn2+ , SAM, and Malonate | | Descriptor: | AprA Methyltransferase 1, GLYCEROL, MALONATE ION, ... | | Authors: | Skiba, M.A, Smith, J.L. | | Deposit date: | 2017-09-21 | | Release date: | 2017-11-15 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.
ACS Chem. Biol., 12, 2017
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6B39
 | | AprA Methyltransferase 1 - GNAT in complex with SAH | | Descriptor: | AprA Methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | Authors: | Skiba, M.A, Smith, J.L. | | Deposit date: | 2017-09-21 | | Release date: | 2017-11-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.392 Å) | | Cite: | A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.
ACS Chem. Biol., 12, 2017
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5UHU
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5THZ
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5THY
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5TZ7
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5TZ6
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