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6BUT
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BU of 6but by Molmil
Solution structure of full-length apo mammalian calmodulin bound to the IQ motif of the human voltage-gated sodium channel NaV1.2
分子名称: Calmodulin-1, Sodium channel protein type 2 subunit alpha
著者Mahling, R, Kilpatrick, A.M, Shea, M.A.
登録日2017-12-11
公開日2019-06-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Na V 1.2 EFL domain allosterically enhances Ca 2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.
Structure, 2021
3IFK
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BU of 3ifk by Molmil
Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90
分子名称: CALCIUM ION, CALMODULIN
著者Witt, T.J, Newman, R.A, Shea, M.A.
登録日2009-07-24
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Thermodynamics and conformational change governing domain-domain interactions of calmodulin.
Methods Enzymol., 466, 2009
3B32
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BU of 3b32 by Molmil
Crystal Structure of Calcium-Saturated Calmodulin N-Terminal Domain Fragment, Residues 1-75
分子名称: CALCIUM ION, Calmodulin
著者Newman, R.A, Shea, M.A.
登録日2007-10-19
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Thermodynamics and conformational change governing domain-domain interactions of calmodulin.
Methods Enzymol., 466, 2009
4RJD
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BU of 4rjd by Molmil
TFP bound in alternate orientations to calcium-saturated Calmodulin C-Domains
分子名称: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CHLORIDE ION, ...
著者Feldkamp, M.D, Gakhar, L, Pandey, N, Shea, M.A.
登録日2014-10-08
公開日2015-08-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Opposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin.
Proteins, 83, 2015
2M5E
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BU of 2m5e by Molmil
Structure of the C-domain of Calcium-saturated Calmodulin bound to the IQ motif of NaV1.2
分子名称: CALCIUM ION, Calmodulin, Sodium channel protein type 2 subunit alpha
著者Fowler, C.A, Feldkamp, M.D, Yu, L, Shea, M.A.
登録日2013-02-21
公開日2014-07-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2.
Biophys. Chem., 224, 2017
2HQW
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BU of 2hqw by Molmil
Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide
分子名称: CALCIUM ION, Calmodulin, Glutamate NMDA receptor subunit zeta 1
著者Akyol, Z, Gakhar, L, Sorensen, B.R, Hell, J.H, Shea, M.A.
登録日2006-07-19
公開日2007-11-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains.
Structure, 15, 2007
2KXW
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BU of 2kxw by Molmil
Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2
分子名称: Calmodulin, Sodium channel protein type 2 subunit alpha
著者Feldkamp, M.D, Yu, L, Shea, M.A.
登録日2010-05-13
公開日2011-04-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and Energetic Determinants of Apo Calmodulin Binding to the IQ Motif of the Na(V)1.2 Voltage-Dependent Sodium Channel.
Structure, 19, 2011

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件を2024-05-15に公開中

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