2R8Q
 
 | | Structure of LmjPDEB1 in complex with IBMX | | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, Class I phosphodiesterase PDEB1, MAGNESIUM ION, ... | | 著者 | Wang, H, Yan, Z, Geng, J, Kunz, S, Seebeck, T, Ke, H. | | 登録日 | 2007-09-11 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the Leishmania major phosphodiesterase LmjPDEB1 and insight into the design of the parasite-selective inhibitors.
Mol.Microbiol., 66, 2007
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3V93
 | | unliganded structure of TcrPDEC1 catalytic domain | | 分子名称: | Cyclic nucleotide specific phosphodiesterase, MAGNESIUM ION, ZINC ION | | 著者 | Wang, H, Kunz, S, Chen, G, Seebeck, T, Wan, Y, Robinson, H, Martinelli, S, Ke, H. | | 登録日 | 2011-12-23 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors.
J.Biol.Chem., 287, 2012
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3V94
 | | TcrPDEC1 catalytic domain in complex with inhibitor wyq16 | | 分子名称: | Cyclic nucleotide specific phosphodiesterase, MAGNESIUM ION, ZINC ION, ... | | 著者 | Wang, H, Kunz, S, Chen, G, Seebeck, T, Wan, Y, Robinson, H, Martinelli, S, Ke, H. | | 登録日 | 2011-12-23 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | TcrPDEC1 catalytic domain in complex with inhibitor wyq16
To be Published
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4I15
 | | Crystal structure of TbrPDEB1 | | 分子名称: | Class 1 phosphodiesterase PDEB1, MAGNESIUM ION, ZINC ION | | 著者 | Wang, H, Ke, H. | | 登録日 | 2012-11-20 | | 公開日 | 2013-03-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Discovery of Novel Trypanosoma brucei Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure.
J.Med.Chem., 56, 2013
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