1JBU
| Coagulation Factor VII Zymogen (EGF2/Protease) in Complex with Inhibitory Exosite Peptide A-183 | 分子名称: | BENZAMIDINE, COAGULATION FACTOR VII, Peptide exosite inhibitor A-183, ... | 著者 | Eigenbrot, C, Kirchhofer, D, Dennis, M.S, Santell, L, Lazarus, R.A, Stamos, J, Ultsch, M.H. | 登録日 | 2001-06-06 | 公開日 | 2001-07-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The factor VII zymogen structure reveals reregistration of beta strands during activation. Structure, 9, 2001
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1SI5
| Protease-like domain from 2-chain hepatocyte growth factor | 分子名称: | hepatocyte growth factor | 著者 | Kirchhofer, D, Yao, X, Peek, M, Eigenbrot, C, Lipari, M.T, Billeci, K.L, Maun, H.R, Moran, P, Santell, L, Lazarus, R.A. | 登録日 | 2004-02-27 | 公開日 | 2004-12-28 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling J.Biol.Chem., 279, 2004
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4AWN
| Structure of recombinant human DNase I (rhDNaseI) in complex with Magnesium and Phosphate. | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Parsiegla, G, Noguere, C, Santell, L, Lazarus, R.A, Bourne, Y. | 登録日 | 2012-06-04 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Structure of Human DNase I Bound to Magnesium and Phosphate Ions Points to a Catalytic Mechanism Common to Members of the DNase I-Like Superfamily. Biochemistry, 51, 2012
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1YBW
| Protease domain of HGFA with no inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hepatocyte growth factor activator precursor | 著者 | Shia, S, Stamos, J, Kirchhofer, D, Fan, B, Wu, J, Corpuz, R.T, Santell, L, Lazarus, R.A, Eigenbrot, C. | 登録日 | 2004-12-21 | 公開日 | 2005-02-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B. J.Mol.Biol., 346, 2005
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1YC0
| short form HGFA with first Kunitz domain from HAI-1 | 分子名称: | Hepatocyte growth factor activator, Kunitz-type protease inhibitor 1, PHOSPHATE ION | 著者 | Shia, S, Stamos, J, Kirchhofer, D, Fan, B, Wu, J, Corpuz, R.T, Santell, L, Lazarus, R.A, Eigenbrot, C. | 登録日 | 2004-12-21 | 公開日 | 2005-02-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B. J.Mol.Biol., 346, 2005
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1DVA
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4K3J
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4O3U
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4O3T
| Zymogen HGF-beta/MET with Zymogen Activator Peptide ZAP.14 | 分子名称: | Hepatocyte growth factor, Hepatocyte growth factor receptor, PENTAETHYLENE GLYCOL, ... | 著者 | Eigenbrot, C, Landgraf, K.E, Steffek, M. | 登録日 | 2013-12-18 | 公開日 | 2014-06-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides. Nat.Chem.Biol., 10, 2014
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1SHY
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