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5G5M
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BU of 5g5m by Molmil
Structure of the Pyrococcus Furiosus Esterase Pf2001 with space group P21
分子名称: ESTERASE, S-methyl hexanethioate
著者Varejao, N, Reverter, D.
登録日2016-05-26
公開日2017-06-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.
Structure, 26, 2018
7P47
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BU of 7p47 by Molmil
Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic
分子名称: E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ...
著者Lascorz, J, Varejao, N, Reverter, D.
登録日2021-07-09
公開日2021-11-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.314 Å)
主引用文献Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs.
Nat Commun, 12, 2021
6I6Z
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BU of 6i6z by Molmil
Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Tyr-Ala-Y(PO2CH2)-homoPhe-OH
分子名称: (2S)-2-{[(S)-{(1R)-1-[(N-acetyl-L-tyrosyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, Carboxypeptidase A1, ZINC ION
著者Gallego, P, Reverter, D.
登録日2018-11-15
公開日2018-12-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes.
J. Med. Chem., 62, 2019
6TXW
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BU of 6txw by Molmil
V30G Transthyretin structure in complex with Tolcalpone
分子名称: Tolcapone, Transthyretin
著者Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S.
登録日2020-01-14
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.153 Å)
主引用文献Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
Febs J., 288, 2021
6TXV
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BU of 6txv by Molmil
A25T Transthyretin structure in complex with Tolcalpone
分子名称: Tolcapone, Transthyretin
著者Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S.
登録日2020-01-14
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
Febs J., 288, 2021
5FQ2
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BU of 5fq2 by Molmil
Crystal structure of human SUMO E1 UFD domain in complex with Ubc9 in a P422 space group.
分子名称: SUMO-ACTIVATING ENZYME SUBUNIT 2, SUMO-CONJUGATING ENZYME UBC9
著者Liu, B, Castano, L, Lois, M, Reverter, D.
登録日2015-12-04
公開日2016-11-16
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Crystal Structure of Human Sumo E1 Ufd Domain in Complex with Ubc9.
To be Published
5FW9
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BU of 5fw9 by Molmil
Human Spectrin SH3 domain D48G, E7Y, K60Y
分子名称: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
著者Gallego, P, Navarro, S, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Human Spectrin SH3 Domain D48G, E7Y, K60Y
To be Published
5FWC
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BU of 5fwc by Molmil
Human Spectrin SH3 domain D48G, E7A, K60A
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, SPECTRIN ALPHA CHAIN, ...
著者Gallego, P, Navarro, S, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Human Spectrin SH3 Domain D48G, E7A, K60A
To be Published
5FW8
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BU of 5fw8 by Molmil
Structure of human transthyretin mutant E89K
分子名称: TRANSTHYRETIN
著者Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW7
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BU of 5fw7 by Molmil
Structure of human transthyretin mutant A109V
分子名称: TRANSTHYRETIN
著者Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FWB
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BU of 5fwb by Molmil
Human Spectrin SH3 domain D48G, E7F, K60F
分子名称: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
著者Gallego, P, Navarro, S, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Human Spectrin SH3 Domain D48G, E7F, K60F
To be Published
6FWD
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BU of 6fwd by Molmil
Crystal structure of human transthyretin double mutant R34G/T119M at pH 5.5
分子名称: Transthyretin
著者Esperante, S, Ventura, S, Reverter, D, Varejao, N.
登録日2018-03-06
公開日2019-03-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
3UIO
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BU of 3uio by Molmil
Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II
分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
著者Gareau, J.R, Reverter, D, Lima, C.D.
登録日2011-11-05
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.
J.Biol.Chem., 287, 2012
3UIN
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BU of 3uin by Molmil
Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2
分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
著者Gareau, J.R, Reverter, D, Lima, C.D.
登録日2011-11-05
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.
J.Biol.Chem., 287, 2012
3UIP
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BU of 3uip by Molmil
Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II
分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
著者Gareau, J.R, Reverter, D, Lima, C.D.
登録日2011-11-05
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.
J.Biol.Chem., 287, 2012
6GUM
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BU of 6gum by Molmil
Structure of the A.thaliana E1 UFD domain in complex with E2
分子名称: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1
著者Liu, B, Lois, L.M, Reverter, D.
登録日2018-06-19
公開日2019-07-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
6GV3
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BU of 6gv3 by Molmil
Structure of the E2 conjugating enzyme, SCE1, from Arabidopsis thaliana.
分子名称: SUMO-conjugating enzyme SCE1
著者Liu, B, Lois, L.M, Reverter, D.
登録日2018-06-20
公開日2019-07-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.201 Å)
主引用文献Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
3ZKF
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BU of 3zkf by Molmil
Structure of LC8 in complex with Nek9 phosphopeptide
分子名称: DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN
著者Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D.
登録日2013-01-22
公開日2013-03-20
最終更新日2013-05-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
J.Biol.Chem., 288, 2013
3ZO5
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BU of 3zo5 by Molmil
Structure of SENP2-Loop1 in complex with preSUMO-2
分子名称: SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 2
著者Alegre, K.O, Reverter, D.
登録日2013-02-20
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Insights Into the Senp6 Loop1 Structure in Complex with Sumo2.
Protein Sci., 23, 2014
3ZKE
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BU of 3zke by Molmil
Structure of LC8 in complex with Nek9 peptide
分子名称: DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN
著者Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D.
登録日2013-01-22
公開日2013-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
J.Biol.Chem., 288, 2013
4A39
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BU of 4a39 by Molmil
Metallo-carboxypeptidase from Pseudomonas Aeruginosa in complex with (2-guanidinoethylmercapto)succinic acid
分子名称: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION
著者Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
登録日2011-09-30
公開日2012-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4AMU
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BU of 4amu by Molmil
Structure of ornithine carbamoyltransferase from Mycoplasma penetrans with a P321 space group
分子名称: ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC
著者Gallego, P, Benach, J, Planell, R, Querol, E, Perez-Pons, J.A, Reverter, D.
登録日2012-03-13
公開日2012-03-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans.
Plos One, 7, 2012
4A38
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BU of 4a38 by Molmil
METALLO-CARBOXYPEPTIDASE FROM PSEUDOMONAS AUREGINOSA IN COMPLEX WITH L-BENZYLSUCCINIC ACID
分子名称: L-BENZYLSUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION
著者Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
登録日2011-09-30
公開日2012-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4A94
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BU of 4a94 by Molmil
Structure of the carboxypeptidase inhibitor from Nerita versicolor in complex with human CPA4
分子名称: CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR, NITRATE ION, ...
著者Covaleda, G, Alonso, M, Chavez, M.A, Aviles, F.X, Reverter, D.
登録日2011-11-23
公開日2011-12-28
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a Novel Metallo-Carboxypeptidase Inhibitor from the Marine Mollusk Nerita Versicolor in Complex with Human Carboxypeptidase A4.
J.Biol.Chem., 287, 2012
4A37
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BU of 4a37 by Molmil
Metallo-carboxypeptidase from Pseudomonas Aeruginosa
分子名称: METALLO-CARBOXYPEPTIDASE, ZINC ION
著者Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
登録日2011-09-30
公開日2012-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012

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