6ZXL
| Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement | 分子名称: | Lethal factor, Protective antigen | 著者 | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | 登録日 | 2020-07-29 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. Plos Pathog., 16, 2020
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6ZXJ
| Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked) | 分子名称: | Lethal factor, Protective antigen | 著者 | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | 登録日 | 2020-07-29 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. Plos Pathog., 16, 2020
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7B16
| TRPC4 in complex with inhibitor GFB-9289 | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one, CALCIUM ION, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-23 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B0S
| TRPC4 in complex with inhibitor GFB-8438 | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-one, CALCIUM ION, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-21 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B1G
| TRPC4 in complex with Calmodulin | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-24 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B0J
| TRPC4 in LMNG detergent | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CALCIUM ION, Transient receptor potential cation channel subfamily c member 4a | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-20 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B05
| TRPC4 in complex with inhibitor GFB-8749 | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-18 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7PXE
| Ca2+ bound Drosophila Slo channel | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | 著者 | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | 登録日 | 2021-10-08 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXF
| Ca2+ free Drosophila Slo channel | 分子名称: | Isoform J of Calcium-activated potassium channel slowpoke, MAGNESIUM ION, POTASSIUM ION | 著者 | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | 登録日 | 2021-10-08 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXG
| Verruculogen-bound Drosophila Slo channel | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | 著者 | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | 登録日 | 2021-10-08 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXH
| Emodepside-bound Drosophila Slo channel | 分子名称: | (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, ... | 著者 | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | 登録日 | 2021-10-08 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PLU
| Cryo-EM structure of the actomyosin-V complex in the rigor state (central 3er/2er) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-01 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PM5
| Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 1er) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PML
| Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (AppNHp, central 1er, class 8) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PMJ
| Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (AppNHp, central 1er, class 6) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PLV
| Cryo-EM structure of the actomyosin-V complex in the rigor state (central 1er, class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-01 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PLW
| Cryo-EM structure of the actomyosin-V complex in the rigor state (central 1er, class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-01 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PLX
| Cryo-EM structure of the actomyosin-V complex in the rigor state (central 1er, class 4) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-01 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PLZ
| Cryo-EM structure of the actomyosin-V complex in the rigor state (central 3er/2er, young JASP-stabilized F-actin) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-01 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PM8
| Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 1er, class 3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PMI
| Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (AppNHp, central 1er, class 5) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PM7
| Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 1er, class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PM9
| Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 1er, class 4) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PMA
| Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 1er, class 5) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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7PME
| Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (AppNHp, central 3er/2er) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | 登録日 | 2021-09-02 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife, 10, 2021
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