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8PBN
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BU of 8pbn by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBU
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BU of 8pbu by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBE
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BU of 8pbe by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBM
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BU of 8pbm by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBJ
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BU of 8pbj by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, GLYCEROL, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBK
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BU of 8pbk by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBP
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BU of 8pbp by Molmil
Mutant R1785C of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBQ
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BU of 8pbq by Molmil
Mutant R1810Q of the dihydroorotase domain of human CAD protein bound to the substrates
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBI
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BU of 8pbi by Molmil
Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
4BS1
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BU of 4bs1 by Molmil
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
Descriptor: ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR (NTRC FAMILY)
Authors:Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S.
Deposit date:2013-06-06
Release date:2013-07-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BT1
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BU of 4bt1 by Molmil
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
Descriptor: ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR
Authors:Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S.
Deposit date:2013-06-12
Release date:2013-07-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BT0
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BU of 4bt0 by Molmil
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
Descriptor: ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR
Authors:Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S.
Deposit date:2013-06-12
Release date:2013-07-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition.
Proc.Natl.Acad.Sci.USA, 110, 2013
2BTY
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BU of 2bty by Molmil
Acetylglutamate kinase from Thermotoga maritima complexed with its inhibitor arginine
Descriptor: ACETYLGLUTAMATE KINASE, ARGININE, N-ACETYL-L-GLUTAMATE, ...
Authors:Gil-Ortiz, F, Fernandez-Murga, M.L, Fita, I, Rubio, V.
Deposit date:2005-06-08
Release date:2005-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Bases of Feed-Back Control of Arginine Biosynthesis, Revealed by the Structure of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga Maritima and Pseudomonas Aeruginosa
J.Mol.Biol., 356, 2006
3ZVY
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BU of 3zvy by Molmil
PHD finger of human UHRF1 in complex with unmodified histone H3 N- terminal tail
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ...
Authors:Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P.
Deposit date:2011-07-28
Release date:2011-12-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers.
Plos One, 6, 2011
6YPO
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BU of 6ypo by Molmil
Arabidopsis aspartate transcarbamoylase bound to UMP
Descriptor: GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-04-16
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
6YS6
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BU of 6ys6 by Molmil
Arabidopsis aspartate transcarbamoylase complex with PALA
Descriptor: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB, ...
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-04-21
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
6YSP
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BU of 6ysp by Molmil
Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate
Descriptor: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-04-23
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
6YW9
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BU of 6yw9 by Molmil
Arabidopsis aspartate transcarbamoylase mutant F161A complex with PALA
Descriptor: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-04-29
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
6YVB
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BU of 6yvb by Molmil
Arabidopsis aspartate transcarbamoylase complex with carbamoyl phosphate
Descriptor: ACETATE ION, GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-04-28
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.826 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
6YY1
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BU of 6yy1 by Molmil
Arabidopsis aspartate transcarbamoylase in apo state
Descriptor: GLYCEROL, PYRB
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-05-04
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
6YWJ
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BU of 6ywj by Molmil
Arabidopsis aspartate transcarbamoylase mutant F161A complex with UMP
Descriptor: GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE
Authors:Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:2020-04-29
Release date:2021-03-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Nat Commun, 12, 2021
2X2W
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BU of 2x2w by Molmil
Acetylglutamate kinase from Escherichia coli bound to N-acetyl-L-glutamyl-5-phosphate
Descriptor: ACETYLGLUTAMATE KINASE, N-ACETYL-L-GLUTAMYL 5-PHOSPHATE, SULFATE ION
Authors:Gil-Ortiz, F, Rubio, V.
Deposit date:2010-01-18
Release date:2010-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations.
J. Mol. Biol., 399, 2010
3ZVZ
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BU of 3zvz by Molmil
PHD finger of human UHRF1
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ZINC ION
Authors:Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P.
Deposit date:2011-07-28
Release date:2011-11-30
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers.
Plos One, 6, 2011
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