7FGQ
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7VEP
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6KDU
| Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | 分子名称: | ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... | 著者 | Ramachandran, R, Shukla, A, Afsar, M. | 登録日 | 2019-07-02 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
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6KJM
| Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | 分子名称: | ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... | 著者 | Ramachandran, R, Shukla, A, Afsar, M. | 登録日 | 2019-07-22 | 公開日 | 2020-07-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A. J.Struct.Biol., 213, 2021
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6KKV
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6KSD
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6KRH
| Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | 分子名称: | ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... | 著者 | Ramachandran, R, Shukla, A, Afsar, M. | 登録日 | 2019-08-21 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
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6KSC
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6LW8
| Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | 分子名称: | (4R)-4-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, DNA ligase A, GLYCEROL, ... | 著者 | Ramachandran, R, Afsar, M, Shukla, A. | 登録日 | 2020-02-07 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A. J.Struct.Biol., 213, 2021
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5JMA
| Crystal structure of Mycobacterium avium SerB2 in complex with serine at catalytic (PSP) domain | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Phosphoserine phosphatase, ... | 著者 | Shree, S, Dubey, S, Agrawal, A, Ramachandran, R. | 登録日 | 2016-04-28 | 公開日 | 2017-05-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Crystal structure of Mycobacterium avium SerB2 in complex with serine at catalytic (PSP) domain To be published
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5JLP
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5T41
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5IS2
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5IT4
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5IT0
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5JLR
| Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, ... | 著者 | Shree, S, Agrawal, A, Dubey, S, Ramachandran, R. | 登録日 | 2016-04-27 | 公開日 | 2017-05-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | 主引用文献 | Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain To be published
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5JJB
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1Z30
| NMR structure of the apical part of stemloop D from cloverleaf 1 of bovine enterovirus 1 RNA | 分子名称: | 5'-R(*GP*GP*CP*GP*UP*UP*CP*GP*UP*UP*AP*GP*AP*AP*CP*GP*UP*C)-3' | 著者 | Ihle, Y, Ohlenschlager, O, Duchardt, E, Ramachandran, R, Gorlach, M. | 登録日 | 2005-03-10 | 公開日 | 2005-04-26 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA Nucleic Acids Res., 33, 2005
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4PCQ
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1M4Y
| Crystal structure of HslV from Thermotoga maritima | 分子名称: | ATP-dependent protease hslV, SODIUM ION | 著者 | Song, H.K, Ramachandran, R, Bochtler, M.B, Hartmann, C, Azim, M.K, Huber, R. | 登録日 | 2002-07-05 | 公開日 | 2003-05-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. BIOPHYS.CHEM., 100, 2003
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2XI1
| Crystal structure of the HIV-1 Nef sequenced from a patient's sample | 分子名称: | NEF | 著者 | Yadav, G.P, Singh, P, Gupta, S, Tripathi, A.K, Tripathi, R.K, Ramachandran, R. | 登録日 | 2010-06-25 | 公開日 | 2011-08-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef. Plos One, 6, 2011
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1RFR
| NMR structure of the 30mer stemloop-D of coxsackieviral RNA | 分子名称: | stemloop-D RNA of the 5'-cloverleaf of coxsackievirus B3 | 著者 | Ohlenschlager, O, Wohnert, J, Bucci, E, Seitz, S, Hafner, S, Ramachandran, R, Zell, R, Gorlach, M. | 登録日 | 2003-11-10 | 公開日 | 2004-03-23 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf
RNA and its interaction with the proteinase 3C. STRUCTURE, 12, 2004
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1HO2
| NMR STRUCTURE OF THE POTASSIUM CHANNEL FRAGMENT L45 IN MICELLES | 分子名称: | VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN | 著者 | Ohlenschlager, O, Hojo, H, Ramachandran, R, Gorlach, M, Haris, P.I. | 登録日 | 2000-12-08 | 公開日 | 2002-06-05 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel. Biophys.J., 82, 2002
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1HO7
| NMR STRUCTURE OF THE POTASSIUM CHANNEL FRAGMENT L45 IN TFE | 分子名称: | VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN | 著者 | Ohlenschlager, O, Hojo, H, Ramachandran, R, Gorlach, M, Haris, P.I. | 登録日 | 2000-12-10 | 公開日 | 2002-06-05 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel. Biophys.J., 82, 2002
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3RB9
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