9AVB
 
 | | Fis1 Wild type | | Descriptor: | CHLORIDE ION, Mitochondrial fission 1 protein | | Authors: | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | | Deposit date: | 2024-03-01 | | Release date: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress.
Nat Commun, 16, 2025
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9AVC
 | | Fis1 Structure Y38E mutation | | Descriptor: | Mitochondrial fission 1 protein | | Authors: | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | | Deposit date: | 2024-03-01 | | Release date: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress.
Nat Commun, 16, 2025
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9AYD
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9AVD
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9AYE
 | | FIS1 T34D Covalent inhibitor complex | | Descriptor: | 2-chloro-N-methyl-N-[3-(10H-phenothiazin-10-yl)propyl]acetamide, Mitochondrial fission 1 protein | | Authors: | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | | Deposit date: | 2024-03-07 | | Release date: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress.
Nat Commun, 16, 2025
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9AVE
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8EUA
 | | Structure of SARS-CoV2 PLpro bound to a covalent inhibitor | | Descriptor: | Papain-like protease nsp3, SULFATE ION, ZINC ION, ... | | Authors: | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | | Deposit date: | 2022-10-18 | | Release date: | 2023-04-05 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.
Nat Commun, 14, 2023
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7UV8
 | | Rad6-Bre1 Complex | | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | | Authors: | Shukla, P.K, Chandrasekharan, M.B. | | Deposit date: | 2022-04-29 | | Release date: | 2023-01-11 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
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7UVC
 | | Rad6(P43L)-Bre1 Complex | | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | | Authors: | Shukla, P.K, Chandrasekharan, M.B. | | Deposit date: | 2022-04-29 | | Release date: | 2023-01-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
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8FYU
 | | Crystal structure of the human CHIP-TPR domain in complex with a 10mer acetylated tau peptide | | Descriptor: | ACE-SER-SER-THR-GLY-SER-ILE-ASP-MET-VAL-ASP, E3 ubiquitin-protein ligase CHIP | | Authors: | Wucherer, K, Bohn, M.F, Basu, K, Nadel, C.M, Gestwicki, J.E, Craik, C.S. | | Deposit date: | 2023-01-26 | | Release date: | 2023-08-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.84839141 Å) | | Cite: | Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP.
Nat Commun, 15, 2024
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