3O0R
| Crystal structure of nitric oxide reductase from Pseudomonas aeruginosa in complex with antibody fragment | Descriptor: | CALCIUM ION, FE (III) ION, HEME C, ... | Authors: | Hino, T, Matsumoto, Y, Nagano, S, Sugimoto, H, Fukumori, Y, Murata, T, Iwata, S, Shiro, Y. | Deposit date: | 2010-07-20 | Release date: | 2010-12-29 | Last modified: | 2013-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of biological N2O generation by bacterial nitric oxide reductase Science, 330, 2010
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1GEB
| X-RAY CRYSTAL STRUCTURE AND CATALYTIC PROPERTIES OF THR252ILE MUTANT OF CYTOCHROME P450CAM | Descriptor: | CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hishiki, T, Shimada, H, Nagano, S, Park, S.-Y, Ishimura, Y. | Deposit date: | 2000-11-01 | Release date: | 2000-11-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center. J.Biochem., 128, 2000
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7E5V
| Crystal structure of Phm7 in complex with inhibitor | Descriptor: | Diels-Alderase, GLYCEROL, SULFATE ION, ... | Authors: | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | Deposit date: | 2021-02-20 | Release date: | 2021-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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7E5T
| Crystal structure of Fsa2 | Descriptor: | Diels-Alderase fsa2, ETHANOL, PENTAETHYLENE GLYCOL, ... | Authors: | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | Deposit date: | 2021-02-20 | Release date: | 2021-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.16977525 Å) | Cite: | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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7E5U
| Crystal structure of Phm7 | Descriptor: | CHLORIDE ION, Diels-Alderase, GLYCEROL, ... | Authors: | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | Deposit date: | 2021-02-20 | Release date: | 2021-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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4XZD
| Crystal Structure of Wild-type HasA from Yersinia pseudotuberculosis | Descriptor: | Extracellular heme acquisition hemophore HasA, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kanadani, M, Hino, T, Nagano, S, Sato, T, Ozaki, S. | Deposit date: | 2015-02-04 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of heme acquisition system A from Yersinia pseudotuberculosis (HasAypt): Roles of the axial ligand Tyr75 and two distal arginines in heme binding J.Inorg.Biochem., 151, 2015
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6KOG
| Ketosynthase domain in tenuazonic acid synthetase 1 (TAS1). | Descriptor: | GLYCEROL, Hybrid PKS-NRPS synthetase TAS1, SULFATE ION | Authors: | Yun, C.S, Nishimoto, K, Motoyama, T, Hino, T, Nagano, S, Osada, H. | Deposit date: | 2019-08-10 | Release date: | 2020-07-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Unique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1. J.Biol.Chem., 295, 2020
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7W8V
| DMSPP- and Trp-bound 6-dimethylallyl tryptophan synthase, IptA | Descriptor: | 6-dimethylallyltryptophan synthase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, SULFATE ION, ... | Authors: | Suemune, H, Nagano, S, Tomoya, H. | Deposit date: | 2021-12-08 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity. Biochem.Biophys.Res.Commun., 593, 2022
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7W8U
| Crystal Structure of Indole Prenyltransferase IptA | Descriptor: | 6-dimethylallyltryptophan synthase | Authors: | Suemune, H, Nagano, S. | Deposit date: | 2021-12-08 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity. Biochem.Biophys.Res.Commun., 593, 2022
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7W8W
| DMSPP- and 5-Me-Trp-bound 6-dimethylallyl tryptophan synthase, IptA | Descriptor: | 5-methyl-L-tryptophan, 6-dimethylallyltryptophan synthase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | Authors: | Suemune, H, Nagano, S, Tomoya, H. | Deposit date: | 2021-12-08 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity. Biochem.Biophys.Res.Commun., 593, 2022
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7W8Y
| DMSPP- and Naplha-Me-Trp-bound 6-dimethylallyl tryptophan synthase, IptA | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-dimethylallyltryptophan synthase, ... | Authors: | Suemune, H, Nagano, S. | Deposit date: | 2021-12-08 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity. Biochem.Biophys.Res.Commun., 593, 2022
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7W8X
| DMSPP- and 6-Me-Trp-bound dimethylallyl tryptophan synthase, IptA | Descriptor: | (2S)-2-azanyl-3-(6-methyl-1H-indol-3-yl)propanoic acid, 6-dimethylallyltryptophan synthase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | Authors: | Suemune, H, Nagano, S, Tomoya, H. | Deposit date: | 2021-12-08 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity. Biochem.Biophys.Res.Commun., 593, 2022
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2Z3U
| Crystal Structure of Chromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1) | Descriptor: | 1,2-ETHANEDIOL, 3,4-DI-1H-INDOL-3-YL-1H-PYRROLE-2,5-DICARBOXYLIC ACID, Cytochrome P450, ... | Authors: | Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. | Deposit date: | 2007-06-06 | Release date: | 2007-07-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton Proc.Natl.Acad.Sci.Usa, 104, 2007
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7VWS
| Carbazole Prenyl Transferase LvqB4 | Descriptor: | 2-methyl-1-[(2R)-2-oxidanylpropyl]-9H-carbazole-3,4-dione, LvqB4, MAGNESIUM ION, ... | Authors: | Suemune, H, Nagata, R, Kuzuyama, T, Nagano, S. | Deposit date: | 2021-11-11 | Release date: | 2022-03-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-Like Enzymes. Angew.Chem.Int.Ed.Engl., 61, 2022
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7VWT
| Carbazole Prenyl Transferase CqsB4 | Descriptor: | 2-methyl-1-[(2R)-2-oxidanylpropyl]-9H-carbazole-3,4-dione, CqsB4, DI(HYDROXYETHYL)ETHER, ... | Authors: | Suemune, H, Nagata, R, Kuzuyama, T, Nagano, S. | Deposit date: | 2021-11-11 | Release date: | 2022-03-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-Like Enzymes. Angew.Chem.Int.Ed.Engl., 61, 2022
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3A1L
| Crystal Structure of 11,11'-Dichlorochromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1) | Descriptor: | 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. | Deposit date: | 2009-04-09 | Release date: | 2009-05-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules J.Am.Chem.Soc., 131, 2009
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2ZF3
| Crystal Structure of VioE | Descriptor: | Hypothetical protein VioE | Authors: | Hirano, S, Shiro, Y, Nagano, S. | Deposit date: | 2007-12-20 | Release date: | 2008-01-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein To be Published
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2ZF4
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7WEW
| Structure of adenylation domain of epsilon-poly-L-lysine synthase | Descriptor: | ADENOSINE-5'-[LYSYL-PHOSPHATE], Epsilon-poly-L-lysine synthase, GLYCEROL, ... | Authors: | Okamoto, T, Yamanaka, K, Hamano, Y, Nagano, S, Hino, T. | Deposit date: | 2021-12-24 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the adenylation domain from an epsilon-poly-l-lysine synthetase provides molecular mechanism for substrate specificity Biochem.Biophys.Res.Commun., 596, 2022
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2Z6B
| Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin | Descriptor: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, Baseplate structural protein Gp27, Tail-associated lysozyme | Authors: | Koshiyama, T, Yokoi, N, Ueno, T, Kanamaru, S, Nagano, S, Shiro, Y, Arisaka, F, Watanabe, Y. | Deposit date: | 2007-07-28 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Molecular design of heteroprotein assemblies providing a bionanocup as a chemical reactor. Small, 4, 2008
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2Z3T
| Crystal Structure of Substrate Free Cytochrome P450 StaP (CYP245A1) | Descriptor: | 1,2-ETHANEDIOL, Cytochrome P450, IMIDAZOLE, ... | Authors: | Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. | Deposit date: | 2007-06-06 | Release date: | 2007-07-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZQJ
| Substrate-Free Form of Cytochrome P450BSbeta | Descriptor: | Cytochrome P450 152A1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Shoji, O, Fujishiro, T, Nagano, S, Hirose, T, Shiro, Y, Watanabe, Y. | Deposit date: | 2008-08-11 | Release date: | 2009-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis. J.Biol.Inorg.Chem., 2010
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2ZQX
| Cytochrome P450BSbeta cocrystallized with heptanoic acid | Descriptor: | Cytochrome P450 152A1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Shoji, O, Fujishiro, T, Nagano, S, Hirose, T, Shiro, Y, Watanabe, Y. | Deposit date: | 2008-08-22 | Release date: | 2009-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis. J.Biol.Inorg.Chem., 2010
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5XB8
| Crystal structure of dibenzothiophene monooxygenase (TdsC) from Paenibacillus sp. A11-2 | Descriptor: | SULFATE ION, Thermophilic dibenzothiophene desulfurization enzyme C | Authors: | Hino, T, Hamamoto, H, Ohshiro, T, Nagano, S. | Deposit date: | 2017-03-16 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.795 Å) | Cite: | Crystal structures of TdsC, a dibenzothiophene monooxygenase from the thermophile Paenibacillus sp. A11-2, reveal potential for expanding its substrate selectivity. J. Biol. Chem., 292, 2017
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5XDD
| Crystal structure of tertiary complex of TdsC from Paenibacillus sp. A11-2 with FMN and Indole | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, INDOLE, ... | Authors: | Hino, T, Hamamoto, H, Ohshiro, T, Nagano, S. | Deposit date: | 2017-03-28 | Release date: | 2017-08-09 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of TdsC, a dibenzothiophene monooxygenase from the thermophile Paenibacillus sp. A11-2, reveal potential for expanding its substrate selectivity. J. Biol. Chem., 292, 2017
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