1YNV
| Asp79 makes a large, unfavorable contribution to the stability of RNase Sa | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | Authors: | Trevino, S.R, Gokulan, K, Newsom, S, Thurlkill, R.L, Shaw, K.L, Mitkevich, V.A, Makarov, A.A, Sacchettini, J.C, Scholtz, J.M, Pace, C.N. | Deposit date: | 2005-01-25 | Release date: | 2005-07-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Asp79 Makes a Large, Unfavorable Contribution to the Stability of RNase Sa. J.Mol.Biol., 354, 2005
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4HAA
| Structure of Ribonuclease Binase Glu43Ala/Phe81Ala Mutant | Descriptor: | Ribonuclease | Authors: | Polyakov, K.M, Trofimov, A.A, Mitchevich, V.A, Dorovatovskii, P.V, Schulga, A.A, Makarov, A.A, Tkach, E.N, Goncharuk, D.A. | Deposit date: | 2012-09-26 | Release date: | 2012-10-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and functional studies of the ribonuclease binase Glu43Ala/Phe81Ala mutant. Acta Crystallogr.,Sect.D, 69, 2013
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5LFY
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2N1S
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3ZL4
| Antibody structural organization: Role of kappa - lambda chain constant domain switch in catalytic functionality | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, A17 ANTIBODY FAB FRAGMENT HEAVY CHAIN, A17 ANTIBODY FAB FRAGMENT LAMBDA LIGHT CHAIN | Authors: | Chatziefthimiou, S.D, Ponomarenko, N.A, Kurkova, I.N, Smirnov, A.V, Smirnov, I.V, Lamzin, V.S, Gabibov, A.G, Wilmanns, M. | Deposit date: | 2013-01-28 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Role of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody Acta Crystallogr.,Sect.D, 70, 2014
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2XZC
| Crystal Structure of phosphonate-modified recombinant A.17 antibody FAB fragment | Descriptor: | 8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL PHENYLPHOSPHONATE, CHLORIDE ION, FAB A.17 HEAVY CHAIN, ... | Authors: | Carletti, E, Nachon, F, Nicolet, Y, Masson, P, Kurkova, I, Smirnov, I, Friboulet, A, Tramontano, A, Gabibov, A. | Deposit date: | 2010-11-24 | Release date: | 2011-09-21 | Last modified: | 2020-03-11 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Reactibodies Generated by Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics. Proc.Natl.Acad.Sci.USA, 108, 2011
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2XZA
| Crystal Structure of recombinant A.17 antibody FAB fragment | Descriptor: | FAB A.17 HEAVY CHAIN, FAB A.17 LIGHT CHAIN | Authors: | Carletti, E, Nachon, F, Nicolet, Y, Masson, P, Kurkova, I, Smirnov, I, Friboulet, A, Tramontano, A, Gabibov, A. | Deposit date: | 2010-11-24 | Release date: | 2011-09-21 | Last modified: | 2020-03-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Reactibodies Generated by Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics. Proc.Natl.Acad.Sci.USA, 108, 2011
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6SUM
| Amicoumacin kinase hAmiN in complex with AMP-PNP, MG2+ and Ami | Descriptor: | ACETATE ION, AMICOUMACIN KINASE, Amicoumacin A, ... | Authors: | Bourenkov, G.P, Mokrushina, Y.A, Terekhov, S.S, Smirnov, I.V, Gabibov, A.G, Altman, S. | Deposit date: | 2019-09-16 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding. Sci Adv, 6, 2020
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6SUL
| Amicoumacin kinase AmiN in complex with AMP-PNP, Mg2+ and Ami | Descriptor: | Amicoumacin A, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Bourenkov, G.P, Mokrushina, Y.A, Terekhov, S.S, Smirnov, I.V, Gabibov, A.G, Altman, S. | Deposit date: | 2019-09-15 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding. Sci Adv, 6, 2020
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6SUI
| AMICOUMACIN KINASE AMIN | Descriptor: | PENTAETHYLENE GLYCOL, Phosphotransferase enzyme family protein | Authors: | Bourenkov, G.P, Mokrushina, Y.A, Terekhov, S.S, Smirnov, I.V, Gabibov, A.G, Altman, S. | Deposit date: | 2019-09-14 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding. Sci Adv, 6, 2020
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6SUN
| Amicoumacin kinase hAmiN in complex with AMP-PNP, Ca2+ and Ami | Descriptor: | APH domain-containing protein, amicoumacin kinase, Amicoumacin A, ... | Authors: | Bourenkov, G.P, Mokrushina, Y.A, Terekhov, S.S, Smirnov, I.V, Gabibov, A.G, Altman, S. | Deposit date: | 2019-09-16 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding. Sci Adv, 6, 2020
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6SV5
| Amicoumacin kinase AmiN in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Phosphotransferase enzyme family protein, amicoumacin kinase | Authors: | Bourenkov, G.P, Mokrushina, Y.A, Terekhov, S.S, Smirnov, I.V, Gabibov, A.G, Altman, S. | Deposit date: | 2019-09-17 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding. Sci Adv, 6, 2020
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