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2O8Z
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BU of 2o8z by Molmil
Bound Structure of CRF1 Extracellular Domain Antagonist
分子名称: cCRF(30-41) Peptide
著者Mesleh, M.F, Shirley, W.A, Heise, C.E, Ling, N, Maki, R.A, Laura, R.P.
登録日2006-12-12
公開日2006-12-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR structural characterization of a minimal peptide antagonist bound to the extracellular domain of the corticotropin-releasing factor1 receptor.
J.Biol.Chem., 282, 2007
1WAZ
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BU of 1waz by Molmil
NMR Structure Determination of the bacterial mercury transporter, MerF, in micelles
分子名称: MERF
著者Howell, S.C, Mesleh, M.F, Opella, S.J.
登録日2004-10-28
公開日2005-04-11
最終更新日2019-04-03
実験手法SOLUTION NMR
主引用文献NMR Structure Determination of a Membrane Protein with Two Transmembrane Helices in Micelles: Merf of the Bacterial Mercury Detoxification System
Biochemistry, 44, 2005
1NH4
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BU of 1nh4 by Molmil
Structure of the coat protein in fd filamentous bacteriophage particles
分子名称: Major coat protein
著者Zeri, A.C, Mesleh, M.F, Nevzorov, A.A, Opella, S.J.
登録日2002-12-18
公開日2003-05-06
最終更新日2022-02-23
実験手法SOLID-STATE NMR
主引用文献Structure of the coat protein in fd filamentous bacteriophage particles determined by solid-state NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 100, 2003
1PI7
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BU of 1pi7 by Molmil
Structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1
分子名称: VPU protein
著者Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J.
登録日2003-05-29
公開日2003-11-11
最終更新日2021-10-27
実験手法SOLID-STATE NMR
主引用文献Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV-1
J.Mol.Biol., 333, 2003
1PI8
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BU of 1pi8 by Molmil
Structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1
分子名称: VPU protein
著者Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J.
登録日2003-05-29
公開日2003-11-11
最終更新日2021-10-27
実験手法SOLID-STATE NMR
主引用文献Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV-1
J.Mol.Biol., 333, 2003
1PJE
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BU of 1pje by Molmil
Structure of the channel-forming trans-membrane domain of Virus protein "u"(Vpu) from HIV-1
分子名称: VPU protein
著者Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J.
登録日2003-06-02
公開日2003-10-14
最終更新日2021-10-27
実験手法SOLID-STATE NMR
主引用文献Three-dimensional structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1
J.Mol.Biol., 333, 2003
5CTX
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BU of 5ctx by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-phenyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, DNA gyrase subunit B, ...
著者Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
登録日2015-07-24
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CPH
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BU of 5cph by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
分子名称: (3E)-3-(pyridin-3-ylmethylidene)-1,3-dihydro-2H-indol-2-one, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit B, ...
著者Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
登録日2015-07-21
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CTW
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BU of 5ctw by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(butanoylamino)thiophene-3-carboxamide, CHLORIDE ION, ...
著者Andersen, O.A, Barker, J, Hadfield, A.T, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
登録日2015-07-24
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CTU
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BU of 5ctu by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4(1H)-one, CHLORIDE ION, ...
著者Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
登録日2015-07-24
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CTY
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BU of 5cty by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ...
著者Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
登録日2015-07-24
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
2C0X
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BU of 2c0x by Molmil
MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA
分子名称: COAT PROTEIN B
著者Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K.
登録日2005-09-08
公開日2005-12-14
最終更新日2020-07-29
実験手法SOLID-STATE NMR
主引用文献Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane.
J.Mol.Biol., 355, 2006
6V0P
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BU of 6v0p by Molmil
PRMT5 complex bound to covalent PBM inhibitor BRD6711
分子名称: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-sulfamoylphenyl)acetamide, CHLORIDE ION, GLYCEROL, ...
著者McMillan, B.J, McKinney, D.C.
登録日2019-11-19
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
7M05
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BU of 7m05 by Molmil
CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988
分子名称: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5
著者McMillan, B.J, McKinney, D.C, Timm, D.E.
登録日2021-03-10
公開日2021-03-17
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021

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