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6DR8
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BU of 6dr8 by Molmil
Metallo-beta-lactamase from Cronobacter sakazakii (Enterobacter sakazakii) HARLDQ motif mutant S60/R118H/Q121H/K254H
分子名称: (2-hydroxyethoxy)acetaldehyde, Beta-lactamase, PHOSPHATE ION, ...
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-06-11
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.476 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse
Protein Cell, 2020
6DQH
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BU of 6dqh by Molmil
Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif
分子名称: Beta-lactamase, PHOSPHATE ION, ZINC ION
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-06-11
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.104 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse
Protein Cell, 2020
6DQ2
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BU of 6dq2 by Molmil
Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif mutant S60
分子名称: Beta-lactamase, PHOSPHATE ION
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-06-10
公開日2019-06-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.158 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse
Protein Cell, 2020
6DN4
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BU of 6dn4 by Molmil
Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif
分子名称: Beta-lactamase
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-06-06
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse
Protein Cell, 2020
8UPP
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BU of 8upp by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with NADPH and Hoe704
分子名称: (2R)-(dimethylphosphoryl)(hydroxy)acetic acid, Ketol-acid reductoisomerase, MAGNESIUM ION, ...
著者Lin, X, Lv, Y, Lonhienne, T, Guddat, L.W.
登録日2023-10-23
公開日2024-04-24
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPN
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BU of 8upn by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with NADP+ and HMKB
分子名称: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ...
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-10-23
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPQ
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BU of 8upq by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with 2,3-dihydroxy-3-isovalerate.
分子名称: (2R)-2,3-dihydroxy-3-methylbutanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-10-23
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
7LAT
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BU of 7lat by Molmil
Campylobacter jejuni keto-acid reductoisomerase in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Guddat, L.W.
登録日2021-01-06
公開日2022-01-12
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8SWM
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BU of 8swm by Molmil
Crystal structure of Campylobacter jejuni ketol-acid reductoisomerase in complex with 2-acetolactate
分子名称: (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase (NADP(+)), ...
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-05-19
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8SXD
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BU of 8sxd by Molmil
Campylobacter jejuni keto-acid reductoisomerase in complex with intermediate and NADP+
分子名称: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ...
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-05-21
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
4DHL
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BU of 4dhl by Molmil
Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment MO07123
分子名称: 1,2-ETHANEDIOL, 2-(4-methylphenyl)-1,3-thiazole-4-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Feder, D, Clayton, D.J, Hussein, W.M, Schenk, G, McGeary, R, Guddat, L.W.
登録日2012-01-29
公開日2012-12-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
6NC5
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BU of 6nc5 by Molmil
Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif
分子名称: ACETATE ION, Beta-lactamase, PHOSPHATE ION, ...
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-12-10
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse.
Protein Cell, 11, 2020
6EYF
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BU of 6eyf by Molmil
Butyrylcolinesterase expressed in CHO cells co-crystallised with a rivastigmine analogue
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, GLYCEROL, ...
著者Brazzolotto, X, De la Mora, E, Dighe, S, Ross, B.
登録日2017-11-12
公開日2018-11-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model
Commun Chem, 2019

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件を2024-05-15に公開中

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