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5Y9T
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Crystal Structure of EGFR T790M mutant in complex with naquotinib
分子名称: 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-2-carboxamide, Epidermal growth factor receptor
著者Mimasu, S, Tomimoto, Y, Maiko, I, Yasushi, A, Tatsuya, N.
登録日2017-08-28
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, inEGFR-Mutated Non-Small Cell Lung Cancer.
Mol. Cancer Ther., 17, 2018

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件を2024-05-15に公開中

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