5EDV
| Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | 分子名称: | E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J. | 登録日 | 2015-10-22 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature, 529, 2016
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7R70
| Crystal Structure of the UbArk2C fusion protein | 分子名称: | GLYCEROL, Ubiquitin,E3 ubiquitin-protein ligase RNF165, ZINC ION | 著者 | Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. | 登録日 | 2021-06-24 | 公開日 | 2022-03-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
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7R71
| Crystal Structure of the UbArk2C-UbcH5b~Ub complex | 分子名称: | Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. | 登録日 | 2021-06-24 | 公開日 | 2022-03-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
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6VH9
| FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, apo form | 分子名称: | Esterase family protein, SODIUM ION | 著者 | Fellner, M, Jamieson, S.A, Brewster, J.L, Mace, P.D. | 登録日 | 2020-01-09 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus . Acs Infect Dis., 6, 2020
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6V0M
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6VHD
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6VHE
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8THI
| Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer) | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT | 著者 | Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A. | 登録日 | 2023-07-16 | 公開日 | 2023-11-22 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter. Elife, 12, 2024
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8THJ
| Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer) | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | 著者 | Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A. | 登録日 | 2023-07-16 | 公開日 | 2023-11-22 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter. Elife, 12, 2024
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8B01
| Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in a nanodisc | 分子名称: | DECANE, DOCOSANE, HEXANE, ... | 著者 | Davies, J.S, North, R.A, Dobson, R.C.J. | 登録日 | 2022-09-06 | 公開日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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7L3L
| Structure of TRAF5 and TRAF6 RING Hetero dimer | 分子名称: | TNF receptor-associated factor 5, TNF receptor-associated factor 6, ZINC ION | 著者 | Das, A, Middleton, A.J, Padala, P, Day, C.L. | 登録日 | 2020-12-17 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structure and ubiquitin binding properties of TRAF RING heterodimers. J.Mol.Biol., 2021
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7QHA
| Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol | 分子名称: | Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ... | 著者 | North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J. | 登録日 | 2021-12-11 | 公開日 | 2022-12-21 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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7T3E
| Structure of the sialic acid bound Tripartite ATP-independent Periplasmic (TRAP) periplasmic component SiaP from Photobacterium profundum | 分子名称: | N-acetyl-beta-neuraminic acid, SULFATE ION, TRAP-type C4-dicarboxylate transport system, ... | 著者 | Davies, J.S, Currie, M.J, North, R.A, Dobson, R.C.J. | 登録日 | 2021-12-07 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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5V60
| Phospho-ERK2 bound to AMP-PCP | 分子名称: | GLYCEROL, MAGNESIUM ION, Mitogen-activated protein kinase 1, ... | 著者 | Lechtenberg, B.C, Riedl, S.J. | 登録日 | 2017-03-15 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. ACS Med Chem Lett, 8, 2017
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5V61
| Phospho-ERK2 bound to bivalent inhibitor SBP2 | 分子名称: | 2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid, 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, ... | 著者 | Lechtenberg, B.C, Riedl, S.J. | 登録日 | 2017-03-15 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. ACS Med Chem Lett, 8, 2017
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5V62
| Phospho-ERK2 bound to bivalent inhibitor SBP3 | 分子名称: | 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, Mitogen-activated protein kinase 1, ... | 著者 | Lechtenberg, B.C, Riedl, S.J. | 登録日 | 2017-03-15 | 公開日 | 2017-07-26 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. ACS Med Chem Lett, 8, 2017
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5VO0
| Structure of a TRAF6-Ubc13~Ub complex | 分子名称: | POTASSIUM ION, TNF receptor-associated factor 6, Ubiquitin, ... | 著者 | Middleton, A.J, Day, C.L. | 登録日 | 2017-05-01 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Nat Commun, 8, 2017
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5VNZ
| Structure of a TRAF6-Ubc13~Ub complex | 分子名称: | TNF receptor-associated factor 6, Ubiquitin, Ubiquitin-conjugating enzyme E2 N, ... | 著者 | Middleton, A.J, Day, C.L. | 登録日 | 2017-05-01 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | 主引用文献 | The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Nat Commun, 8, 2017
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