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Solution structure of the primary host recognition region of complement factor H
分子名称:	COMPLEMENT FACTOR H
著者	Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N.
登録日	2005-08-18
公開日	2006-03-22
最終更新日	2011-07-13
実験手法	SOLUTION NMR
主引用文献	Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure. J.Biol.Chem., 281, 2006

Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y)
分子名称:	COMPLEMENT FACTOR H
著者	Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N.
登録日	2007-02-16
公開日	2007-03-20
最終更新日	2018-05-02
実験手法	SOLUTION NMR
主引用文献	Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007

Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H)
分子名称:	COMPLEMENT FACTOR H
著者	Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N.
登録日	2007-02-16
公開日	2007-03-20
最終更新日	2018-05-02
実験手法	SOLUTION NMR
主引用文献	Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007

NS3/NS4A protease with inhibitor
分子名称:	(2R,6S,13aR,14aR,16aS)-6-{[(cyclopentyloxy)carbonyl]amino}-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxooctadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 3,4-dihydroisoquinoline-2(1H)-carboxylate, NS4A peptide, Serine protease NS3, ...
著者	Zhang, H, Ballard, J, Vigers, G.P.A, Brandhuber, B.J.
登録日	2013-05-20
公開日	2013-08-07
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease. J.Med.Chem., 57, 2014