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6EG2
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BU of 6eg2 by Molmil
Crystal structure of human BRM in complex with compound 16
分子名称: ISOPROPYL ALCOHOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2, N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea
著者Zhu, X, Kulathila, R, Hu, T, Xie, X.
登録日2018-08-17
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
J. Med. Chem., 61, 2018
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件を2024-05-15に公開中

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