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5LIT
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Structure of the DNA duplex d(AAATTT)2 with the potential antiparasitic drug 6XV at 1.25 A resolution
Descriptor: 4-((4,5-dihydro-1H-imidazol-2-yl)amino)-N-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzamide dihydrochloride, DNA (5'-D(*AP*AP*AP*TP*TP*T)-3'), MAGNESIUM ION
Authors:Millan, C.R, Dardonville, C, de Koning, H.P, Saperas, N, Lourdes Campos, J.
Deposit date:2016-07-15
Release date:2017-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Nucleic Acids Res., 45, 2017

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