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3U10
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BU of 3u10 by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
4KL1
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BU of 4kl1 by Molmil
HCN4 CNBD in complex with cGMP
分子名称: ACETATE ION, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ...
著者Lolicato, M, Arrigoni, C, Zucca, S, Nardini, M, Bucchi, A, Schroeder, I, Simmons, K, Bolognesi, M, DiFrancesco, D, Schwede, F, Fishwick, C.W.G, Johnson, A.P.K, Thiel, G, Moroni, A.
登録日2013-05-07
公開日2014-04-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Nat.Chem.Biol., 10, 2014
3U0Z
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BU of 3u0z by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U11
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BU of 3u11 by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
4RUE
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BU of 4rue by Molmil
Human K2P4.1 (TRAAK) potassium channel, G124I mutant
分子名称: POTASSIUM ION, Potassium channel subfamily K member 4
著者Lolicato, M, Minor, D.L.Jr.
登録日2014-11-19
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.
Neuron, 84, 2014
4RUF
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BU of 4ruf by Molmil
Human K2P4.1 (TRAAAK) potassium channel, W262S mutant
分子名称: POTASSIUM ION, Potassium channel subfamily K member 4
著者Lolicato, M, Minor, D.L.Jr.
登録日2014-11-19
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.
Neuron, 84, 2014
6W7B
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BU of 6w7b by Molmil
K2P2.1 (TREK-1), 0 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-19
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W84
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BU of 6w84 by Molmil
K2P2.1 (TREK-1), 200 mM K+
分子名称: CADMIUM ION, DODECANE, N-OCTANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8A
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BU of 6w8a by Molmil
K2P2.1 (TREK-1):ML335 complex, 10 mM K+
分子名称: CADMIUM ION, DODECANE, HEXADECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8F
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BU of 6w8f by Molmil
K2P2.1 (TREK-1):ML335 complex, 0 mM K+
分子名称: CADMIUM ION, DODECANE, HEXADECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W7D
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BU of 6w7d by Molmil
K2P2.1 (TREK-1), 10 mM K+
分子名称: CADMIUM ION, DODECANE, HEXADECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-19
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W82
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BU of 6w82 by Molmil
K2P2.1 (TREK-1), 50 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W86
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BU of 6w86 by Molmil
K2P2.1 (TREK-1):ML335 complex, 100 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.299 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6CQ6
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BU of 6cq6 by Molmil
K2P2.1(TREK-1) apo structure
分子名称: CADMIUM ION, DECANE, POTASSIUM ION, ...
著者Lolicato, M, Minor, D.L.
登録日2018-03-14
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
6CQ9
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BU of 6cq9 by Molmil
K2P2.1(TREK-1):ML402 complex
分子名称: CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ...
著者Lolicato, M, Minor, D.L.
登録日2018-03-14
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
6W7E
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BU of 6w7e by Molmil
K2P2.1 (TREK-1), 30 mM K+
分子名称: CADMIUM ION, DODECANE, HEXADECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-19
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W83
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BU of 6w83 by Molmil
K2P2.1 (TREK-1), 100 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.901 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W87
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BU of 6w87 by Molmil
K2P2.1 (TREK-1):ML335 complex, 50 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6CQ8
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BU of 6cq8 by Molmil
K2P2.1(TREK-1):ML335 complex
分子名称: CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ...
著者Lolicato, M, Minor, D.L.
登録日2018-03-14
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
6W85
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BU of 6w85 by Molmil
K2P2.1 (TREK-1):ML335 complex, 200 mM K+
分子名称: CADMIUM ION, DECANE, HEXADECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8C
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BU of 6w8c by Molmil
K2P2.1 (TREK-1):ML335 complex, 1 mM K+
分子名称: CADMIUM ION, DODECANE, HEXADECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W88
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BU of 6w88 by Molmil
K2P2.1 (TREK-1):ML335 complex, 30 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W7C
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BU of 6w7c by Molmil
K2P2.1 (TREK-1), 1 mM K+
分子名称: CADMIUM ION, DECANE, DODECANE, ...
著者Lolicato, M, Minor, D.L.
登録日2020-03-19
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
7PGB
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BU of 7pgb by Molmil
NaV_Ae1/Sp1CTD_pore-SAT09 complex
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
分子名称: ANT05 H12 fab fragment, heavy chain, light chain, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022

 

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