6KY6
| Crystal structure of a thermostable aldo-keto reductase Tm1743 in complexs with inhibitor epalrestat in space group P3221cc | 分子名称: | 2,5-diketo-D-gluconic acid reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zhang, C.Y, Min, Z.Z, Liu, X.M, Wang, C, Tang, W.R. | 登録日 | 2019-09-16 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima. Febs Lett., 594, 2020
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8J5J
| The crystal structure of bat coronavirus RsYN04 RBD bound to the antibody S43 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nano antibody S43 | 著者 | Zhao, R.C, Niu, S, Han, P, Qi, J.X, Gao, G.F, Wang, Q.H. | 登録日 | 2023-04-23 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus. Zool.Res., 44, 2023
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2G6U
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7V3Z
| Structure of cannabinoid receptor type 1(CB1) | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, CHOLESTEROL, FLAVIN MONONUCLEOTIDE, ... | 著者 | Liu, Z.J, Shen, L, Hua, T, Yao, D.Q, Wu, L.J. | 登録日 | 2021-08-12 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | 主引用文献 | A Genetically Encoded F-19 NMR Probe Reveals the Allosteric Modulation Mechanism of Cannabinoid Receptor 1. J.Am.Chem.Soc., 143, 2021
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3PZE
| JNK1 in complex with inhibitor | 分子名称: | 3-(carbamoylamino)-5-phenylthiophene-2-carboxamide, Mitogen-activated protein kinase 8, SULFATE ION | 著者 | Xue, Y. | 登録日 | 2010-12-14 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas. J.Med.Chem., 55, 2012
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3AL4
| Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Zhang, W, Qi, J.X, Shi, Y, Li, Q, Yan, J.H, Gao, G.F. | 登録日 | 2010-07-22 | 公開日 | 2010-08-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.872 Å) | 主引用文献 | Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus Protein Cell, 1, 2010
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1ONS
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3BU7
| Crystal Structure and Biochemical Characterization of GDOsp, a Gentisate 1,2-Dioxygenase from Silicibacter Pomeroyi | 分子名称: | FE (II) ION, Gentisate 1,2-dioxygenase | 著者 | Chen, J, Wang, M.Z, Zhu, G.Y, Zhang, X.C, Rao, Z.H. | 登録日 | 2008-01-02 | 公開日 | 2008-08-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure and mutagenic analysis of GDOsp, a gentisate 1,2-dioxygenase from Silicibacter pomeroyi. Protein Sci., 17, 2008
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3NSS
| The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active sites | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | 著者 | Li, Q, Qi, J.X, Zhang, W, Vavricka, C.J, Shi, Y, Gao, G.F. | 登録日 | 2010-07-02 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | 主引用文献 | The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site Nat.Struct.Mol.Biol., 17, 2010
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5NGH
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5YOC
| Crystal Structure of flavodoxin with engineered disulfide bond C102-R125C | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL | 著者 | Pu, M, Xu, Z, Song, G, Liu, Z.J. | 登録日 | 2017-10-27 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Protein crystal quality oriented disulfide bond engineering. Protein Cell, 9, 2018
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5YOG
| Crystal Structure of flavodoxin with engineered disulfide bond N14C-C93 | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL, ... | 著者 | Pu, M, Xu, Z, Song, G, Liu, Z.J. | 登録日 | 2017-10-27 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Protein crystal quality oriented disulfide bond engineering. Protein Cell, 9, 2018
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5YO4
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5YO5
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5YOE
| Crystal Structure of flavodoxin with engineered disulfide bond A43C-L74C | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL | 著者 | Pu, M, Xu, Z, Song, G, Liu, Z.J. | 登録日 | 2017-10-27 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Protein crystal quality oriented disulfide bond engineering. Protein Cell, 9, 2018
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5YO3
| Crystal Structure of B562RIL with engineered disulfide bond V16C-A29C | 分子名称: | SULFATE ION, Soluble cytochrome b562 | 著者 | Pu, M, Xu, Z, Song, G, Liu, Z.J. | 登録日 | 2017-10-26 | 公開日 | 2018-05-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Protein crystal quality oriented disulfide bond engineering. Protein Cell, 9, 2018
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5YOB
| Crystal Structure of flavodoxin without engineered disulfide bond | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL | 著者 | Pu, M, Xu, Z, Song, G, Liu, Z.J. | 登録日 | 2017-10-27 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.142 Å) | 主引用文献 | Protein crystal quality oriented disulfide bond engineering. Protein Cell, 9, 2018
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5YM7
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5YO6
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6L6Z
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6LFG
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5UEW
| BRD2 Bromodomain2 with A-1360579 | 分子名称: | Bromodomain-containing protein 2, N-[3-(4-methoxy-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-4-phenoxyphenyl]methanesulfonamide | 著者 | Park, C.H. | 登録日 | 2017-01-03 | 公開日 | 2017-05-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors. J. Med. Chem., 60, 2017
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5UEY
| BRD4_BD2_A-1412838 | 分子名称: | 5-[2-(2,4-difluorophenoxy)-5-{[ethyl(dihydroxy)-lambda~4~-sulfanyl]amino}phenyl]-4-ethoxy-1-methylpyridin-2(1H)-one, Bromodomain-containing protein 4 | 著者 | Park, C.H. | 登録日 | 2017-01-03 | 公開日 | 2017-05-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors. J. Med. Chem., 60, 2017
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5UEX
| BRD4_BD2_A-1497627 | 分子名称: | 17-{[ethyl(dihydroxy)-lambda~4~-sulfanyl]amino}-11,13-difluoro-2-methyl-6,7,8,9-tetrahydrodibenzo[4,5:7,8][1,6]dioxacyclododecino[3,2-c]pyridin-3(2H)-one, Bromodomain-containing protein 4 | 著者 | Park, C.H. | 登録日 | 2017-01-03 | 公開日 | 2017-05-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors. J. Med. Chem., 60, 2017
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5UEU
| BRD4_BD2_A-1107604 | 分子名称: | Bromodomain-containing protein 4, methyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate | 著者 | Park, C.H. | 登録日 | 2017-01-03 | 公開日 | 2017-05-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors. J. Med. Chem., 60, 2017
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