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5G5W
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BU of 5g5w by Molmil
Structure guided design and discovery of Indazole ethers as highly potent, non-steroidal Glucocorticoid receptor modulators
Descriptor: 1,2-ETHANEDIOL, 2,2,2-trifluoro-N-[(1R,2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-phenylpropan-2-yl]acetamide, GLUCOCORTICOID RECEPTOR, ...
Authors:Hemmerling, M, Edman, K, Lepisto, M, Eriksson, A, Ivanova, S, Dahmen, J, Rehwinkel, H, Berger, M, Hendrickx, R, Dearman, M, Jellesmark-Jensen, T, Wissler, L, Hansson, T.
Deposit date:2016-06-08
Release date:2017-02-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Indazole Ethers as Novel, Potent, Non-Steroidal Glucocorticoid Receptor Modulators.
Bioorg.Med.Chem.Lett., 26, 2017
6RO1
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BU of 6ro1 by Molmil
X-ray crystal structure of the MTR4 NVL complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ...
Authors:Lingaraju, M, Langer, L.M, Basquin, J, Falk, S, Conti, E.
Deposit date:2019-05-10
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.
Nat Commun, 10, 2019
6UID
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BU of 6uid by Molmil
Structure of the cytoplasmic domain of the T3SS sorting platform protein PscD from P. aeruginosa
Descriptor: EscD/YscD/HrpQ family type III secretion system inner membrane ring protein
Authors:Muthuramalingam, M, Lovell, S, Battaile, K.P, Picking, W.D.
Deposit date:2019-09-30
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform.
J.Mol.Biol., 432, 2020
6UIE
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BU of 6uie by Molmil
Structure of the cytoplasmic domain of the T3SS sorting platform protein PscK from P. aeruginosa
Descriptor: CHLORIDE ION, Type III export protein PscK
Authors:Muthuramalingam, M, Lovell, S, Battaile, K.P, Picking, W.D.
Deposit date:2019-09-30
Release date:2020-10-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform.
J.Mol.Biol., 432, 2020
1BE1
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BU of 1be1 by Molmil
GLUTAMATE MUTASE (B12-BINDING SUBUNIT), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: GLUTAMATE MUTASE
Authors:Tollinger, M, Konrat, R, Hilbert, B.H, Marsh, E.N.G, Kraeutler, B.
Deposit date:1998-05-19
Release date:1998-08-26
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum
Structure, 6, 1998
1ID8
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BU of 1id8 by Molmil
NMR STRUCTURE OF GLUTAMATE MUTASE (B12-BINDING SUBUNIT) COMPLEXED WITH THE VITAMIN B12 NUCLEOTIDE
Descriptor: 2-HYDROXY-PROPYL-AMMONIUM, METHYLASPARTATE MUTASE S CHAIN, PHOSPHORIC ACID MONO-[5-(5,6-DIMETHYL-BENZOIMIDAZOL-1-YL)-4-HYDROXY-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER
Authors:Tollinger, M, Eichmuller, C, Konrat, R, Huhta, M.S, Marsh, E.N.G, Krautler, B.
Deposit date:2001-04-04
Release date:2001-06-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The B(12)-binding subunit of glutamate mutase from Clostridium tetanomorphum traps the nucleotide moiety of coenzyme B(12).
J.Mol.Biol., 309, 2001
1CLM
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BU of 1clm by Molmil
STRUCTURE OF PARAMECIUM TETRAURELIA CALMODULIN AT 1.8 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, CALMODULIN
Authors:Sundaralingam, M.
Deposit date:1993-01-23
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Paramecium tetraurelia calmodulin at 1.8 A resolution.
Protein Sci., 2, 1993
1KVW
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BU of 1kvw by Molmil
CARBOXYLIC ESTER HYDROLASE, SINGLE MUTANT H48Q OF BOVINE PANCREATIC PLA2 ENZYME
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1998-04-24
Release date:1998-11-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2.
Acta Crystallogr.,Sect.D, 55, 1999
1KVY
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BU of 1kvy by Molmil
CARBOXYLIC ESTER HYDROLASE, SINGLE MUTANT D49E COORDINATED TO CALCIUM
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1998-04-29
Release date:1998-11-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2.
Acta Crystallogr.,Sect.D, 55, 1999
1OSA
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BU of 1osa by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT PARAMECIUM TETRAURELIA CALMODULIN AT 1.68 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, CALMODULIN
Authors:Sundaralingam, M.
Deposit date:1993-08-11
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure of the recombinant Paramecium tetraurelia calmodulin at 1.68 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
4TNC
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BU of 4tnc by Molmil
REFINED STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN C IN THE TWO-CALCIUM STATE AT 2-ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, TROPONIN C
Authors:Sundaralingam, M.
Deposit date:1987-09-28
Release date:1988-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution.
J.Biol.Chem., 263, 1988
1FDK
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BU of 1fdk by Molmil
CARBOXYLIC ESTER HYDROLASE (PLA2-MJ33 INHIBITOR COMPLEX)
Descriptor: 1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL, CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-09-04
Release date:1998-10-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of the complex of bovine pancreatic phospholipase A2 with the inhibitor 1-hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol,.
Biochemistry, 36, 1997
1UNE
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BU of 1une by Molmil
CARBOXYLIC ESTER HYDROLASE, 1.5 ANGSTROM ORTHORHOMBIC FORM OF THE BOVINE RECOMBINANT PLA2
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-11-05
Release date:1998-05-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution refinement of orthorhombic bovine pancreatic phospholipase A2.
Acta Crystallogr.,Sect.D, 55, 1999
1TOP
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BU of 1top by Molmil
STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN-C AT 1.78 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, SULFATE ION, TROPONIN C
Authors:Sundaralingam, M.
Deposit date:1993-08-11
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of chicken skeletal muscle troponin C at 1.78 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
1KVX
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BU of 1kvx by Molmil
CARBOXYLIC ESTER HYDROLASE, SINGLE MUTANT D99A OF BOVINE PANCREATIC PLA2, 1.9 A ORTHORHOMBIC FORM
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1998-04-28
Release date:1998-11-18
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2.
Acta Crystallogr.,Sect.D, 55, 1999
2BPP
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BU of 2bpp by Molmil
PHOSPHOLIPASE A2 ENGINEERING. X-RAY STRUCTURAL AND FUNCTIONAL EVIDENCE FOR THE INTERACTION OF LYSINE-56 WITH SUBSTRATES
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1992-01-17
Release date:1993-10-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Biochemistry, 30, 1991
1BPQ
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BU of 1bpq by Molmil
PHOSPHOLIPASE A2 ENGINEERING. X-RAY STRUCTURAL AND FUNCTIONAL EVIDENCE FOR THE INTERACTION OF LYSINE-56 WITH SUBSTRATES
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1991-10-28
Release date:1993-10-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Biochemistry, 30, 1991
1MKV
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BU of 1mkv by Molmil
CARBOXYLIC ESTER HYDROLASE COMPLEX (PLA2 + TRANSITION STATE ANALOG COMPLEX)
Descriptor: 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-09-13
Release date:1998-03-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure of the complex of bovine pancreatic phospholipase A2 with a transition-state analogue.
Acta Crystallogr.,Sect.D, 54, 1998
1NCY
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BU of 1ncy by Molmil
TROPONIN-C, COMPLEX WITH MANGANESE
Descriptor: MANGANESE (II) ION, SULFATE ION, TROPONIN C
Authors:Sundaralingam, M, Rao, S.T.
Deposit date:1996-06-02
Release date:1997-01-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structures of Mn, Cd and Tb metal complexes of troponin C.
Acta Crystallogr.,Sect.D, 52, 1996
1NCZ
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BU of 1ncz by Molmil
TROPONIN C
Descriptor: SULFATE ION, TERBIUM(III) ION, TROPONIN C
Authors:Sundaralingam, M, Rao, S.T.
Deposit date:1996-06-02
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structures of Mn, Cd and Tb metal complexes of troponin C.
Acta Crystallogr.,Sect.D, 52, 1996
1NCX
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BU of 1ncx by Molmil
TROPONIN C
Descriptor: CADMIUM ION, SULFATE ION, TROPONIN C
Authors:Sundaralingam, M, Rao, S.T.
Deposit date:1996-06-02
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structures of Mn, Cd and Tb metal complexes of troponin C.
Acta Crystallogr.,Sect.D, 52, 1996
1MKT
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BU of 1mkt by Molmil
CARBOXYLIC ESTER HYDROLASE, 1.72 ANGSTROM TRIGONAL FORM OF THE BOVINE RECOMBINANT PLA2 ENZYME
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-09-06
Release date:1998-03-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:1.72 A resolution refinement of the trigonal form of bovine pancreatic phospholipase A2.
Acta Crystallogr.,Sect.D, 54, 1998
1IRB
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BU of 1irb by Molmil
CARBOXYLIC ESTER HYDROLASE
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-08-13
Release date:1997-12-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
Biochemistry, 35, 1996
1MKS
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BU of 1mks by Molmil
CARBOXYLIC ESTER HYDROLASE, TRIGONAL FORM OF THE TRIPLE MUTANT
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-08-27
Release date:1997-12-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99.
Biochemistry, 36, 1997
1MKU
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BU of 1mku by Molmil
CARBOXYLIC ESTER HYDROLASE, ORTHORHOMBIC FORM OF THE TRIPLE MUTANT
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1997-09-10
Release date:1997-12-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99.
Biochemistry, 36, 1997

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