9CFL
 
 | | Cryo-EM structure of S. aureus TarGH in complex with ATP-gamma-S | | Descriptor: | Lauryl Maltose Neopentyl Glycol, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Li, F.K.K, Worrall, L.J, Strynadka, N.C.J. | | Deposit date: | 2024-06-27 | | Release date: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Nat Commun, 16, 2025
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6UEX
 | | Crystal structure of S. aureus LcpA in complex with octaprenyl-pyrophosphate-GlcNAc | | Descriptor: | 2-(acetylamino)-2-deoxy-1-O-[(S)-hydroxy{[(S)-hydroxy{[(2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]oxy}phosphoryl]oxy}phosphoryl]-alpha-D-glucopyranose, GLYCEROL, Regulatory protein MsrR, ... | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2019-09-23 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
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6UF6
 | | Crystal structure of B. subtilis TagU | | Descriptor: | GLYCEROL, Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU, SULFATE ION | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2019-09-23 | | Release date: | 2020-01-29 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
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6UF3
 | | Crystal structure of B. subtilis TagV | | Descriptor: | Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2019-09-23 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
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6UF5
 | | Crystal structure of B. subtilis TagT | | Descriptor: | Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagT | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2019-09-23 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
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8V33
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8V34
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8VA1
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6XH9
 | | Crystal structure of S. aureus TarJ | | Descriptor: | Ribulose-5-phosphate reductase 1 | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2020-06-18 | | Release date: | 2021-04-21 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
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6XHK
 | | Crystal structure of S. aureus TarJ in complex with NADPH | | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Ribulose-5-phosphate reductase 1 | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2020-06-18 | | Release date: | 2021-04-21 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
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6XHP
 | | Crystal structure of S. aureus TarI (space group C121) | | Descriptor: | Ribitol-5-phosphate cytidylyltransferase 1, TETRAETHYLENE GLYCOL | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2020-06-19 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
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6XHQ
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6XHS
 | | Crystal structure of S. aureus TarI in complex with CTP (space group P1211) | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribitol-5-phosphate cytidylyltransferase 1, ... | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2020-06-19 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
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6XHR
 | | Crystal structure of S. aureus TarI (space group P1211) | | Descriptor: | Ribitol-5-phosphate cytidylyltransferase 1, THIOCYANATE ION | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2020-06-19 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
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6XHT
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9CFP
 | | Cryo-EM structure of S. aureus TarGH in complex with AMP-PNP and targocil-II | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Targocil-II, ... | | Authors: | Peters, S.C, Worrall, L.J, Strynadka, N.C.J. | | Deposit date: | 2024-06-27 | | Release date: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Nat Commun, 16, 2025
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9MHU
 | | Cryo-EM structure of S. aureus TarGH in complex with Targocil-II and ATP-gamma-S in a catalytically competent conformation | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Targocil-II, ... | | Authors: | Peters, S.C, Worrall, L.J, Strynadka, N.C.J. | | Deposit date: | 2024-12-12 | | Release date: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Nat Commun, 16, 2025
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9MHD
 | | Cryo-EM structure of S. aureus TarGH in complex with ATP-gamma-S | | Descriptor: | Lauryl Maltose Neopentyl Glycol, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Peters, S.C, Worrall, L.J, Strynadka, N.C.J. | | Deposit date: | 2024-12-11 | | Release date: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Nat Commun, 16, 2025
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9MHZ
 | | Cryo-EM structure of S. aureus TarGH in complex with Targocil-II and ATP-gamma-S in a catalytically incompetent conformation | | Descriptor: | Lauryl Maltose Neopentyl Glycol, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Peters, S.C, Worrall, L.J, Strynadka, N.C.J. | | Deposit date: | 2024-12-12 | | Release date: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Nat Commun, 16, 2025
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5T9C
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5T9B
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5T91
 | | Crystal structure of B. subtilis 168 GlpQ in complex with bicine | | Descriptor: | BICINE, CALCIUM ION, Glycerophosphoryl diester phosphodiesterase, ... | | Authors: | Li, F.K.K, Strynadka, N.C.J. | | Deposit date: | 2016-09-09 | | Release date: | 2016-11-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.
J. Biol. Chem., 291, 2016
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