6TIN
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6TIH
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6TIB
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6TIE
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6TIJ
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6ZXU
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6ZXX
| Catabolic reductive dehalogenase NpRdhA, N-terminally tagged. | 分子名称: | 3 bromo 4 hydroxybenzoic acid, 3,5-bis(bromanyl)-4-oxidanyl-benzoic acid, BROMIDE ION, ... | 著者 | Leys, D, Halliwell, T. | 登録日 | 2020-07-30 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope. Microorganisms, 8, 2020
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6ZY1
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6ZY0
| Catabolic reductive dehalogenase NpRdhA, N-terminally tagged, K488Q variant | 分子名称: | CHLORIDE ION, COBALAMIN, IRON/SULFUR CLUSTER, ... | 著者 | Leys, D, Halliwell, T. | 登録日 | 2020-07-30 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope. Microorganisms, 8, 2020
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7ABN
| Structure of the reversible pyrrole-2-carboxylic acid decarboxylase PA0254/HudA | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, IMIDAZOLE, MANGANESE (II) ION, ... | 著者 | Leys, D. | 登録日 | 2020-09-08 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence. Acs Catalysis, 11, 2021
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7ABO
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4O4P
| Structure of P450 BM3 A82F F87V in complex with S-omeprazol | 分子名称: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Leys, D. | 登録日 | 2013-12-19 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Human P450-like oxidation of diverse proton pump inhibitor drugs by 'gatekeeper' mutants of flavocytochrome P450 BM3. Biochem.J., 460, 2014
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4OQS
| Crystal structure of CYP105AS1 | 分子名称: | CYP105AS1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Leys, D. | 登録日 | 2014-02-10 | 公開日 | 2015-02-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc.Natl.Acad.Sci.USA, 112, 2015
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4OQR
| Structure of a CYP105AS1 mutant in complex with compactin | 分子名称: | CYP105AS1, Mevastatin, Compactin, ... | 著者 | Leys, D. | 登録日 | 2014-02-10 | 公開日 | 2015-02-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc.Natl.Acad.Sci.USA, 112, 2015
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4L54
| Structure of cytochrome P450 OleT, ligand-free | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Terminal olefin-forming fatty acid decarboxylase | 著者 | Leys, D. | 登録日 | 2013-06-10 | 公開日 | 2013-11-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium. J.Biol.Chem., 289, 2014
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4L40
| Structure of the P450 OleT with a C20 fatty acid substrate bound | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Terminal olefin-forming fatty acid decarboxylase, icosanoic acid | 著者 | Leys, D. | 登録日 | 2013-06-07 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium. J.Biol.Chem., 289, 2014
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3CXY
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3CXV
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3CY0
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3CXX
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3CY1
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3EKB
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5LW6
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4KEW
| structure of the A82F BM3 heme domain in complex with omeprazole | 分子名称: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Leys, D. | 登録日 | 2013-04-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
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4KF0
| Structure of the A82F P450 BM3 heme domain | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Leys, D. | 登録日 | 2013-04-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
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