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4OW6
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BU of 4ow6 by Molmil
Crystal structure of Diphtheria Toxin at acidic pH
Descriptor: Diphtheria toxin
Authors:Leka, O, Vallese, F, Pirazzini, M, Berto, P, Montecucco, C, Zanotti, G.
Deposit date:2014-01-31
Release date:2014-04-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Diphtheria toxin conformational switching at acidic pH.
Febs J., 281, 2014
8HKH
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BU of 8hkh by Molmil
Crystal structure of the LC/A1-DARPin18 complex
Descriptor: BoNT/A, Designed ankyrin repeat protein 18, ZINC ION
Authors:Wu, Y, Leka, O, Kammerer, R.
Deposit date:2022-11-26
Release date:2023-11-29
Last modified:2025-01-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A DARPin promotes faster onset of botulinum neurotoxin A1 action.
Nat Commun, 14, 2023
7DVL
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BU of 7dvl by Molmil
Crystal Structure of the Catalytic Domain of Botulinum Neurotoxin Subtype A3
Descriptor: Bont/A3, ZINC ION
Authors:Wu, Y, Leka, O, Kammerer, R, Li, X.
Deposit date:2021-01-13
Release date:2021-04-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structure of the catalytic domain of botulinum neurotoxin subtype A3.
J.Biol.Chem., 296, 2021
9F25
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BU of 9f25 by Molmil
Cryo-EM structure of Botulinum neurotoxin A LC-HN domain
Descriptor: Botulinum neurotoxin type A
Authors:Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R.
Deposit date:2024-04-22
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
9F2J
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BU of 9f2j by Molmil
Cryo-EM structure of SV2B-BoNT/A1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ...
Authors:Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R.
Deposit date:2024-04-23
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
9F2B
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BU of 9f2b by Molmil
Focused refinement of SV2B luminal domain and BoNT/A1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ...
Authors:Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R.
Deposit date:2024-04-22
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
9F1R
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BU of 9f1r by Molmil
Cryo-EM structure of SV2B-Hc-A1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin A heavy chain, ...
Authors:Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R.
Deposit date:2024-04-20
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
9F2Y
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BU of 9f2y by Molmil
Focused refinement of SV2B-LD-BoNT/A1 at pH 5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ...
Authors:Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R.
Deposit date:2024-04-24
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
9F3C
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BU of 9f3c by Molmil
Low-resolution (5.4 angstrom) cryo-EM structure of SV2B-BoNT/A1 at pH 5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ...
Authors:Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R.
Deposit date:2024-04-25
Release date:2025-03-12
Method:ELECTRON MICROSCOPY (5.41 Å)
Cite:Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
7OH1
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BU of 7oh1 by Molmil
Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1
Descriptor: FAB TT110, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021
7OH0
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BU of 7oh0 by Molmil
Tetanus neurotoxin HC domain in complex with TT104-Fab1
Descriptor: Fab TT104, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021

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PDB entries from 2025-05-28

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