4X21
 
 | | The MAP kinase JNK3 as target for halogen bonding | | 分子名称: | CHLORIDE ION, Mitogen-activated protein kinase 10, N-ethyl-4-{[4-(1H-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide | | 著者 | Lange, A, Buettner, F.M, Guenther, M.B, Zimmermann, M.O, Hennig, S, Laufer, S.A, Stehle, T, Boeckler, F. | | 登録日 | 2014-11-25 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond.
J.Am.Chem.Soc., 137, 2015
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1XSW
 | | The solid-state NMR structure of Kaliotoxin | | 分子名称: | Kaliotoxin 1 | | 著者 | Lange, A, Becker, S, Seidel, K, Giller, K, Pongs, O, Baldus, M. | | 登録日 | 2004-10-20 | | 公開日 | 2005-04-05 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | A Concept for Rapid Protein-Structure Determination by Solid-State NMR Spectroscopy
Angew.Chem.Int.Ed.Engl., 44, 2005
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2L0T
 | | Solution structure of the complex of ubiquitin and the VHS domain of Stam2 | | 分子名称: | Signal transducing adapter molecule 2, Ubiquitin | | 著者 | Lange, A, Hoeller, D, Wienk, H, Marcillat, O, Lancelin, J, Walker, O. | | 登録日 | 2010-07-15 | | 公開日 | 2010-12-15 | | 最終更新日 | 2012-03-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin.
Biochemistry, 50, 2011
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2X9C
 | | Crystal structure of a soluble PrgI mutant from Salmonella Typhimurium | | 分子名称: | PROTEIN PRGI | | 著者 | Poyraz, O, Schmidt, H, Seidel, K, Delissen, F, Ader, C, Tenenboim, H, Goosmann, C, Laube, B, Thuenemann, A.F, Zychlinsky, A, Baldus, M, Lange, A, Griesinger, C, Kolbe, M. | | 登録日 | 2010-03-15 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Protein Refolding is Required for Assembly of the Type Three Secretion Needle
Nat.Struct.Mol.Biol., 17, 2010
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2KJ3
 | | High-resolution structure of the HET-s(218-289) prion in its amyloid form obtained by solid-state NMR | | 分子名称: | Small s protein | | 著者 | Van Melckebeke, H, Wasmer, C, Lange, A, AB, E, Loquet, A, Meier, B.H. | | 登録日 | 2009-05-20 | | 公開日 | 2010-06-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic-Resolution Three-Dimensional Structure of HET-s(218-289) Amyloid Fibrils by Solid-State NMR Spectroscopy
J.Am.Chem.Soc., 132, 2010
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4D07
 | | DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a tail | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT (II) ION, DYNEIN LIGHT CHAIN 2, ... | | 著者 | Bodor, A, Radnai, L, Hetenyi, C, Rapali, P, Lang, A, Kover, K.E, Perczel, A, Wahlgren, W.Y, Katona, G, Nyitray, L. | | 登録日 | 2014-04-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity.
Biochemistry, 53, 2014
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1JJ9
 | | Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition | | 分子名称: | 2-HYDROXY-5-[4-(2-HYDROXY-ETHYL)-PIPERIDIN-1-YL]-5-PHENYL-1H-PYRIMIDINE-4,6-DIONE, CALCIUM ION, Matrix Metalloproteinase 8, ... | | 著者 | Brandstetter, H, Grams, F, Glitz, D, Lang, A, Huber, R, Bode, W, Krell, H.-W, Engh, R.A. | | 登録日 | 2001-07-04 | | 公開日 | 2001-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition.
J.Biol.Chem., 276, 2001
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2KV7
 | | NMR solution structure of a soluble PrgI mutant from Salmonella Typhimurium | | 分子名称: | Protein prgI | | 著者 | Schmidt, H, Poyraz, O, Seidel, K, Delissen, F, Ader, C, Tenenboim, H, Goosmann, C, Laube, B, Thuenemann, A.F, Zychlinski, A, Baldus, M, Lange, A, Griesinger, C, Kolbe, M. | | 登録日 | 2010-03-09 | | 公開日 | 2010-06-16 | | 最終更新日 | 2019-12-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Protein refolding is required for assembly of the type three secretion needle.
Nat.Struct.Mol.Biol., 17, 2010
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2LPZ
 | | Atomic model of the Type-III Secretion System Needle | | 分子名称: | Protein prgI | | 著者 | Loquet, A, Sgourakis, N.G, Gupta, R, Giller, K, Riedel, D, Goosmann, C, Griesinger, C, Kolbe, M.G, Baker, D, Becker, S, Lange, A. | | 登録日 | 2012-02-21 | | 公開日 | 2012-05-16 | | 最終更新日 | 2021-08-18 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic model of the type III secretion system needle.
Nature, 486, 2012
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1UN0
 | | Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment | | 分子名称: | IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2 | | 著者 | Matsuura, Y, Lange, A, Harreman, M.T, Corbett, A.H, Stewart, M. | | 登録日 | 2003-09-03 | | 公開日 | 2003-10-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import
Embo J., 22, 2003
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2MME
 | | Hybrid structure of the Shigella flexneri MxiH Type three secretion system needle | | 分子名称: | MxiH | | 著者 | Demers, J.P, Habenstein, B, Loquet, A, Vasa, S.K, Becker, S, Baker, D, Lange, A, Sgourakis, N.G. | | 登録日 | 2014-03-14 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å), SOLID-STATE NMR | | 主引用文献 | High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy.
Nat Commun, 5, 2014
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2MEX
 | | Structure of the tetrameric building block of the Salmonella Typhimurium PrgI Type three secretion system needle | | 分子名称: | Protein PrgI | | 著者 | Loquet, A, Habenstein, B, Chevelkov, V, Giller, K, Becker, S, Lange, A. | | 登録日 | 2013-10-01 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-01-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic structure and handedness of the building block of a biological assembly.
J.Am.Chem.Soc., 135, 2013
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2MSG
 | | Solid-state NMR structure of ubiquitin | | 分子名称: | Ubiquitin | | 著者 | Lakomek, N, Habenstein, B, Loquet, A, Shi, C, Giller, K, Wolff, S, Becker, S, Fasshuber, H, Lange, A. | | 登録日 | 2014-08-04 | | 公開日 | 2015-02-18 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR.
Protein Sci., 24, 2015
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2N7H
 | | Hybrid structure of the Type 1 Pilus of Uropathogenic E.coli | | 分子名称: | FimA | | 著者 | Habenstein, B, Loquet, A, Giller, K, Vasa, S, Becker, S, Habeck, M, Lange, A. | | 登録日 | 2015-09-11 | | 公開日 | 2015-09-23 | | 最終更新日 | 2015-10-14 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Angew.Chem.Int.Ed.Engl., 54, 2015
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6YEG
 | | Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - Final EM Refinement | | 分子名称: | Tail tube protein gp17.1* | | 著者 | Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A. | | 登録日 | 2020-03-24 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | | 主引用文献 | Architecture of the flexible tail tube of bacteriophage SPP1.
Nat Commun, 11, 2020
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6YQ5
 | | Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - NMR Ensemble | | 分子名称: | Tail tube protein gp17.1* | | 著者 | Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A. | | 登録日 | 2020-04-16 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | | 主引用文献 | Architecture of the flexible tail tube of bacteriophage SPP1.
Nat Commun, 11, 2020
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2RNM
 | | Structure of The HET-s(218-289) prion in its amyloid form obtained by solid-state NMR | | 分子名称: | Small s protein | | 著者 | Wasmer, C, Lange, A, Van Melckebeke, H, Siemer, A, Riek, R, Meier, B.H. | | 登録日 | 2008-01-24 | | 公開日 | 2008-04-01 | | 最終更新日 | 2015-07-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core
Science, 319, 2008
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1RFN
 | | HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | | 分子名称: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | | 著者 | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | | 登録日 | 1999-04-19 | | 公開日 | 1999-09-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding.
Structure Fold.Des., 7, 1999
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2N3D
 | | Atomic structure of the cytoskeletal bactofilin BacA revealed by solid-state NMR | | 分子名称: | Bactofilin A | | 著者 | Shi, C, Fricke, P, Lin, L, Chevelkov, V, Wegstroth, M, Giller, K, Becker, S, Thanbichler, M, Lange, A. | | 登録日 | 2015-05-29 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR.
Sci Adv, 1, 2015
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2UVS
 | | High Resolution Solid-state NMR structure of Kaliotoxin | | 分子名称: | POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.1 | | 著者 | Korukottu, J, Lange, A, Vijayan, V, Schneider, R, Pongs, O, Becker, S, Baldus, M, Zweckstetter, M. | | 登録日 | 2007-03-14 | | 公開日 | 2008-05-27 | | 最終更新日 | 2020-01-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Conformational Plasticity in Ion Channel Recognition of a Peptide Toxin
To be Published
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8TJ2
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6V8Y
 | | Structure of a Sodium Potassium ion Channel | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... | | 著者 | Roy, R, Weiss, K.L, Coates, L. | | 登録日 | 2019-12-12 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural plasticity of the selectivity filter in a nonselective ion channel.
Iucrj, 8, 2021
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3ND2
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3JC9
 | | Architectural model of the type IVa pilus machine in a non-piliated state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PilA, ... | | 著者 | Chang, Y.-W, Rettberg, L.A, Jensen, G.J. | | 登録日 | 2015-11-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Architecture of the type IVa pilus machine.
Science, 351, 2016
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3JC8
 | | Architectural model of the type IVa pilus machine in a piliated state | | 分子名称: | LysM domain protein, PilA, PilN, ... | | 著者 | Chang, Y.-W, Rettberg, L.A, Jensen, G.J. | | 登録日 | 2015-11-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Architecture of the type IVa pilus machine.
Science, 351, 2016
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