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Factor Xa in complex with BAY59-7939
Descriptor:	5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION
Authors:	Roehrig, S, Straub, A, Pohlmann, J, Lampe, T, Pernerstorfer, J, Schlemmer, K, Reinemer, P, Perzborn, E, Schaefer, M.
Deposit date:	2008-10-24
Release date:	2008-11-11
Last modified:	2021-04-28
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	Discovery of the Novel Antithrombotic Agent 5-Chloro-N-({(5S)-2-Oxo-3- [4-(3-Oxomorpholin-4-Yl)Phenyl]-1,3-Oxazolidin-5-Yl}Methyl)Thiophene-2- Carboxamide (Bay 59-7939): An Oral, Direct Factor Xa Inhibitor. J.Med.Chem., 48, 2005

Crystal structure of soluble guanylate cyclase activator runcaciguat (BAY 1101042) bound to nostoc H-NOX domain
Descriptor:	CHLORIDE ION, GLYCEROL, H-NOX domain protein, ...
Authors:	van den Akker, F, Kumar, V, Schaefer, M.
Deposit date:	2021-01-20
Release date:	2021-05-05
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042). J.Med.Chem., 64, 2021