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Factor Xa in complex with the inhibitor 1-[6-methyl-4,5,6,7-tetrahydrothiazolo(5,4-c)pyridin-2-yl] carbonyl-2-carbamoyl-4-(6-chloronaphth-2-ylsulphonyl)piperazine
Descriptor:	(2R)-4-[(6-CHLORO-2-NAPHTHYL)SULFONYL]-1-[(5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]PIPERAZ INE-2-CARBOXAMIDE, CALCIUM ION, Coagulation factor X, ...
Authors:	Suzuki, M.
Deposit date:	2003-11-07
Release date:	2004-11-07
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding element J.Med.Chem., 47, 2004

FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID
Descriptor:	(2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID, BLOOD COAGULATION FACTOR XA, CALCIUM ION
Authors:	Kamata, K, Kim, S.H.
Deposit date:	1998-03-19
Release date:	1999-03-23
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc.Natl.Acad.Sci.USA, 95, 1998

FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID
Descriptor:	(2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID, BLOOD COAGULATION FACTOR XA, CALCIUM ION
Authors:	Kamata, K, Kim, S.H.
Deposit date:	1998-03-19
Release date:	1999-03-23
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc.Natl.Acad.Sci.USA, 95, 1998

CRYSTAL STRUCTURE OF THE INHIBITOR ZK-807834 (CI-1031) COMPLEXED WITH FACTOR XA
Descriptor:	CALCIUM ION, CHLORIDE ION, COAGULATION FACTOR XA, ...
Authors:	Adler, M, Whitlow, M.
Deposit date:	2000-08-08
Release date:	2000-10-04
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Preparation, characterization, and the crystal structure of the inhibitor ZK-807834 (CI-1031) complexed with factor Xa. Biochemistry, 39, 2000